Sentences with phrase «memory cell population»

Different clonal memory cell populations had different B cell or macrophage helper compositions that matched effector cell populations generated much earlier in the response.

Herpesvirus entry mediator (TNFRSF14) regulates the persistence of T helper memory cell populations.

Antibody titres are not boosted significantly, memory cell populations are not expanded.

Not exact matches

«By combining the genetic analysis of a small population of immune cells from healthy skin with functional experiments we were able to define two subgroups of memory immune cell and in detail decipher / dissect how these cells behave in healthy and inflamed skin,» explains Liv Eidsmo, researcher at Karolinska Institutet's Department of Medicine.

«It was once believed that effector and memory cells arose as two distinct populations, with some cells initially fated to be effector type and some to be memory,» McDonald said.

The population of T cells that remains are tissue resident memory cells, which live long term in skin and, when functioning properly, should be fighting infection.

When an entire population is observed, rather than individual cells, the bacteria appear to develop a kind of collective memory.

She said that a failure to maintain NFkB signals at this point, or even after memory T cells have been produced, leads to a loss of the population of memory T cells that have been generated after the infection.

Neuroscientists Jing Wang and Freda Miller, both then at Toronto's Hospital for Sick Children, showed that when nondiabetic mice are given metformin, their memory improves, thanks to an increase in the neural stem cell population and in the number of these cells that develop into healthy neurons in the hippocampus, the brain's memory center.

We describe a scalable platform that uses genomic DNA for analog, rewritable, and flexible memory distributed across living cell populations.

Genomically encoded analog memory with precise in vivo DNA writing in living cell populations

The ingenol derivative activates a population called central memory cells.

The new study from Tonegawa's group builds on previous research demonstrating that episodic memories are physically represented in populations of cells in parts of the hippocampus.

Student's t tests excluding the outlier indicated a p - value of < 0.04 for the remaining five pandemic H1N1 samples compared with the IgG memory and germinal center (GC) cells or the primary IgG plasmablast responses (0.2 with EM included) and a p - value of < 0.0001 against the IgM populations.

«The successful retrieval of memories in AD mice by increasing the number of spines for normal memory processing only in the memory cells, rather than in a broad population of cells, highlights the importance of highly - targeted manipulation of neurons and their circuits for future therapies.

When you're an adult, you have a population of T cells that give you your immune memory for lifetime.

«The successful retrieval of memories in AD mice by increasing the number of spines for normal memory processing only in the memory cells, rather than in a broad population of cells, highlights the importance of highly - targeted manipulation of neurons and their circuits for future therapies,» said Tonegawa in a statement.

The hallmark of an effective T cell response is the formation of a stable long - lived population of cells that mediate immune memory.

Memory CD4 + T cells, whose survival and expansion showed no requirements for MHC molecules at all, dampened the space - induced expansion of naive cells, showing that the two populations are not independent in their requirements for peripheral niches.

This is the first description of a human memory T cell population that is susceptible to being lost through end - stage differentiation due to the combined effects of lifelong virus reactivation in the presence of bystander differentiation - inducing factors.

This novel pattern of a virus - specific CD8 + T cell response suggests that continuous or repetitive exposure to Ag can slowly mold memory T cell populations over time.

The evidence against neonicotinoids now exists in key bee brain cells involved in learning and memory, in whole bees, entire colonies and now at the level of whole populations of wild bees.