Sentences with phrase «memory in rodents»

The Morris water maze is a valuable tool to study learning and memory in rodents.

Here, we examined the extent to which performance in the Morris water maze — the most frequently used behavioral assay of spatial learning and memory in rodents — translates to humans.

Also, an amelioration of the pathogenic processes was demonstrated in the hippocampus, which is the site of memory in rodents.

In recent years, neuroscientists have devised several ways to erase memories in rodents.

Not exact matches

«The findings are encouraging because they are consistent with rodent literature that pinpoints exactly the parts of the brain that play a role in stress - induced memory benefits caused by exercise.»

DHA supplementation in rodents and nonhuman primates leads to increased brain DHA concentrations and enhanced performance on a wide variety of learning, memory, and problem - solving tasks (19 — 21).

In other studies, Sonntag's group has shown that infusing IGF - 1 into the brain improves memory and learning in elderly rodentIn other studies, Sonntag's group has shown that infusing IGF - 1 into the brain improves memory and learning in elderly rodentin elderly rodents.

Adult mice and other rodents sprout new nerve cells in memory - related parts of their brains.

In spring a band of brainy rodents made headlines for zipping through mazes and mastering memory tricks.

A potential bridge is a process called long - term potentiation (LTP), a type of synaptic strengthening that has been scrutinized in slices of rodent hippocampus and is widely considered a likely physiological basis for memory.

Many of the same molecules have been implicated in both declarative and nondeclarative memory and in species as varied as sea slugs, fruit flies, and rodents, suggesting that the molecular machinery for memory has been widely conserved.

Elderly rodents that received human umbilical cord blood improved significantly in memory tests

Using rodent models of opiate addiction, Dr. Laviolette's research has shown that opiates affect pathways of associative memory formation in multiple ways, both at the level of anatomy (connections between neurons) and at the molecular levels (how molecules inside the brain affect these connections).

«Alzheimer's drug repairs brain damage after alcohol binges in rodents: Drug appears to reverse structural and genetic brain changes that affect memory, learning.»

In previous studies on rodents, postdoctoral scholar Clemenson and others showed that exploring the environment resulted in the growth of new neurons that became entrenched in the hippocampus» memory circuit and increased neuronal signaling networkIn previous studies on rodents, postdoctoral scholar Clemenson and others showed that exploring the environment resulted in the growth of new neurons that became entrenched in the hippocampus» memory circuit and increased neuronal signaling networkin the growth of new neurons that became entrenched in the hippocampus» memory circuit and increased neuronal signaling networkin the hippocampus» memory circuit and increased neuronal signaling networks.

Although the precise role of neurogenesis in memory is still controversial, more than a decade of research has demonstrated that boosting neurogenesis with exercise and antidepressants such as Prozac can increase rodents» ability to learn new information about places and events.

But a compound previously used to enhance memory in mice may offer hope: Rodents who took it up to a month after a concussion had memory capabilities similar to those that had never been injured.

Using a rodent model of opiate addiction, Laviolette's team found that the process of opiate addiction and withdrawal triggered a switch between two molecular pathways in the amygdala controlling how opiate addiction memories were formed.

As the mice developed, Verma's team found that the rodents» brains were only a third of their normal size, with particularly striking reductions in brain areas involved in learning and memory.

To test the long - term spatial memory of mice, the scientists trained the rodents to spot a new object placed in a controlled environment where two objects of similar shape and volume stand.

«Our findings with rodents suggest that that it may be possible to reduce or even prevent learning and memory impairments through a derivative of the same chemical compound found in beer,» he said.

In two new studies, researchers have found a way to stimulate the brains of rodents to activate a specific memory trace.

It was one of the most mind - bending scientific reports in 2014: Injecting old mice with the plasma portion of blood from young mice seemed to improve the elderly rodents» memory and ability to learn.

To Mayford, this suggests that when the mice got the drug in the first round of the experiment, it caused a bland memory to be muddled with a bad one, thereby hampering the rodents» ability to learn.

However, stimulation of targets in the lateral hypothalamus in rodents during learning resulted in improved performance on tests of subsequent memory.11

The theta rhythm (3 to 8 Hz) is a large EEG potential recorded from the hippocampus in rodents and humans29, 37 and is thought to aid formation of memories.37 It has been suggested that resetting of the phase of the theta rhythm improves memory performance by allowing the best possible encoding of novel stimuli.38 Stimulation of the perforant pathway in rodents induces resetting of the theta phase and produces favorable conditions for long - term potentiation.9, 39 In four subjects in our study who had contacts implanted in the entorhinal region and ipsilateral hippocampus, we observed theta - phase resetting in the hippocampus during stimulation of the entorhinal regioin rodents and humans29, 37 and is thought to aid formation of memories.37 It has been suggested that resetting of the phase of the theta rhythm improves memory performance by allowing the best possible encoding of novel stimuli.38 Stimulation of the perforant pathway in rodents induces resetting of the theta phase and produces favorable conditions for long - term potentiation.9, 39 In four subjects in our study who had contacts implanted in the entorhinal region and ipsilateral hippocampus, we observed theta - phase resetting in the hippocampus during stimulation of the entorhinal regioin rodents induces resetting of the theta phase and produces favorable conditions for long - term potentiation.9, 39 In four subjects in our study who had contacts implanted in the entorhinal region and ipsilateral hippocampus, we observed theta - phase resetting in the hippocampus during stimulation of the entorhinal regioIn four subjects in our study who had contacts implanted in the entorhinal region and ipsilateral hippocampus, we observed theta - phase resetting in the hippocampus during stimulation of the entorhinal regioin our study who had contacts implanted in the entorhinal region and ipsilateral hippocampus, we observed theta - phase resetting in the hippocampus during stimulation of the entorhinal regioin the entorhinal region and ipsilateral hippocampus, we observed theta - phase resetting in the hippocampus during stimulation of the entorhinal regioin the hippocampus during stimulation of the entorhinal region.

«Much of extinction training — the process of learning that a fearful cue is no longer fearful — in adult rodents closely parallels aspects of exposure - based psychotherapy for humans, where an exposure to a stimulus that was associated with trauma shares many aspects of the initial traumatic memories.»

Theta rhythms are very strong in rodent hippocampi and entorhinal cortex during learning and memory retrieval, and are believed to be vital to the induction of long - term potentiation, a potential cellular mechanism of learning and memory.

Based upon activity in multiple CNS toxicity assays, we identified an exceptionally potent, orally active, neurotrophic molecule called J147 that facilitates memory in normal rodents, and prevents the loss of synaptic proteins and cognitive decline when administered to three - month - old APP / swePS1ΔE9 mice for seven months [7].

Walter's team has also found that the unfolded protein response influences memory consolidation in rodents, suggesting a role in human cognitive impairment.

Scopolamine - induced memory impairment in rodents is a well established model of memory dysfunction based upon acetylcholine metabolism [90].

Male rodents given access to a running wheel early in life show increased neural activity and improved memory as adults.

Researchers have known for some time that exercise produces these chemicals in rodents, and that more exercise leads to a larger hippocampus — a brain region important for memory.

Changes in the time it takes the rodent to find the platform in a series of successive trials can be used as a measure of spatial learning and memory.

The researchers can rewrite bad memories with precision in mice, such as by switching a memory about the aforementioned yucky - tasting (to rodents) quinine water with a good memory of interacting with a desired member of the opposite sex.

In other research a rodent model of TBI was used to show that CNB - 001 significantly reversed the behavioural deficits in both locomotion and memory that come with the brain injurIn other research a rodent model of TBI was used to show that CNB - 001 significantly reversed the behavioural deficits in both locomotion and memory that come with the brain injurin both locomotion and memory that come with the brain injury.

Drugs that block these receptors have been shown to block the formation of fearful memories and to reduce the anxiety associated with alcohol withdrawal in rodents.»

Almost all of the humour otherwise involves the pigeons flying into objects and one another and the smelly fat one (Ricky Gervais) burping and flatulating, while a late appearance by a pair of rodent French freedom fighters uncomfortably pings off the parents in the audience's cobwebbed memories of The Rescuers.