Sentences with phrase «men with aggressive prostate cancer»

Men with aggressive prostate cancer that has stopped responding to conventional treatment could potentially benefit from a new class of cancer drug designed to overcome drug resistance, a new study suggests.

Dr Chris Parker, Chair of the NCRI's Prostate Cancer Clinical Studies Group, said: «There's a need to develop better tests to identify and monitor men with aggressive prostate cancer.

Not exact matches

«Genetic association with aggressive prostate cancer discovered: Study showed a threefold increase in the risk of aggressive prostate cancer for men with the genetic mutation..»

Depressed men with localized prostate cancer were more likely to be diagnosed with more aggressive prostate cancer, received less effective treatments and survived for shorter times than prostate cancer patients who were not depressed, a UCLA study has found.

Researchers at the Universities of Bristol and Oxford found that testing asymptomatic men with PSA detects some disease that would be unlikely to cause any harm but also misses some aggressive and lethal prostate cancers.

Of greater concern were the higher rates of prostate cancer classified as aggressive: It developed in 6.4 % of the men in the finasteride group, compared with 5.1 % in the placebo group.

Patients with aggressive prostate cancer, the second - leading cause of cancer deaths among men, had RNase L abnormalities too.

«For men with prostate cancer, emotional distress may lead to more aggressive treatment.»

«Emotional distress may motivate men with low - risk prostate cancer to choose more aggressive treatment, such as choosing surgery over active surveillance,» said UB's Heather Orom, the lead author on the study, published in the February issue of the Journal of Urology.

Similarly men with these gene variants were three times more likely to be diagnosed with aggressive prostate cancer (Gleason 8 or more).

«These genes are found in between 6 and 14 % of men» said Alexandre Zlotta, «This makes it one of, if not the, most common genes yet found to be associated with aggressive prostate cancer.

Since most men with prostate cancer have indolent (non-aggressive) disease for which conservative therapy or surveillance would be appropriate treatment, the clinical challenge is not only how to identify those with prostate cancer, but also how to distinguish those who would benefit from surgical or other aggressive treatment from those who would not.

This is the first population - based study to compare the follow - up intensity of American men with prostate cancer who have not undergone aggressive treatment with those who opted to undergo various forms of aggressive therapy, such as surgery and radiation.

After following 154 men with low - risk prostate cancer for 38 months, the investigators found that low levels of free testosterone were significantly linked with an increased risk of developing more aggressive disease.

Men with BRCA1 / 2 mutations who develop prostate cancer tend to develop these cancers at an earlier age than average and may develop more aggressive forms of the disease.

Men with these mutations are more likely than non-carriers to contract aggressive, lethal prostate cancer, to be diagnosed at a more advanced stage and to ultimately die of the disease, researchers say.

Men with low - risk prostate cancer who previously had to choose between aggressive treatment, with the potential for significant side effects, and active surveillance, with the risk of disease progression, may have a new option.

Low Cholesterol May Shrink Risk for High - Grade Prostate Cancer Men with lower cholesterol are less likely than those with higher levels to develop high - grade prostate cancer, an aggressive form of the disease with a poorer prognosis, according to results of a Johns Hopkins collaborativProstate Cancer Men with lower cholesterol are less likely than those with higher levels to develop high - grade prostate cancer, an aggressive form of the disease with a poorer prognosis, according to results of a Johns Hopkins collaborative Cancer Men with lower cholesterol are less likely than those with higher levels to develop high - grade prostate cancer, an aggressive form of the disease with a poorer prognosis, according to results of a Johns Hopkins collaborativprostate cancer, an aggressive form of the disease with a poorer prognosis, according to results of a Johns Hopkins collaborative cancer, an aggressive form of the disease with a poorer prognosis, according to results of a Johns Hopkins collaborative study.

BUFFALO, N.Y. — Although men with prostate cancer usually respond to standard treatment with hormone therapy or chemotherapy, many will eventually experience progression or recurrence despite treatment — particularly those with high - risk or aggressive forms of the disease.

While men with the more aggressive form of the cancer make up about 5 % of the 180,000 to 200,000 cases of prostate cancer in the U.S. each year, and only 12 % will have these mutations, that population is still at considerably higher risk of developing advanced disease.

The findings also hint that in coming years, it may be possible to use the panel not just among men with advanced disease but to distinguish between men who develop the slower growing type of prostate cancer from the more aggressive type.

Men with prostate cancer who have had a past infection with the sexually transmitted germ Trichomonas vaginalis are at higher risk of having an aggressive form of cancer compared to prostate cancer patients who have never had the STD, a new study suggests

Men with a variant may develop earlier and more aggressive prostate cancer.

The researchers looked at one hundred seventy - seven men with an aggressive form of prostate cancer who had submitted to prostatectomies and were at high risk for recurrence.

The researchers concluded that men with a PSA level above 2 ng / ml at age 60 should be considered at increased risk of aggressive prostate cancer and should continue to be screened regularly.