Sentences with phrase «menengioma tumor the size»

In fact, a single dose decreased tumor size by 60 percent over a three - week period.

A combination of fostamatinib and paclitaxel reduced tumor size in six mice by up to 87 percent, compared with no shrinkage in six untreated animals after three weeks.

After five weeks, the combination treatment in the six mice decreased tumor size by up to 66 percent, compared with six mice treated with only paclitaxel.

Shih, Wang and their colleagues tested fostamatinib's power to reduce tumor size in mice implanted with human ovarian cancer cells that were resistant to paclitaxel.

The three study groups had a similar distribution of baseline characteristics, with the exception of tumor size.

BPTES not encased in the nanoparticle delivery system had little effect on tumor size in 12 human tumor - bearing mice.

Injecting spores of C. novyi into dogs resulted in rapid reduction of tumor sizes, and even completely eradicated tumors in three of 16 trial dogs.

BPTES has been used in animal models for a variety of cancers but has not substantially reduced tumor sizes, probably because the drug concentration in tumor tissue is not high enough when using conventional drug formulation methods, say the scientists.

While Paclitaxel treatment alone can lead to a decrease in tumor size, there is a large risk of relapse once the treatment is terminated.

Outcomes were excellent irrespective of patient age at diagnosis, tumor size, and tumor grade.

This led to a significant reduction in tumor size.

It was observed to shrink tumor size in humans by up to 25 % in safety trials.

Tumor size in mice injected with the antibody steadily decreased over time, while their survival increased.

The study measured overall reduction in tumor size and then compared this reduction to the time until a controlled tumor started to grow (PFS) and patient overall survival (OS).

The research team also found that treating mice with an antibody that blocked the galectin - 9 / dectin - 1 interaction dramatically reduced tumor size and increased survival.

In two mouse models of pancreatic cancer, a single treatment consisting of intravenous delivery of the PMILs followed by localized delivery of near - infrared light to the tumor site via optical fibers resulted in significantly greater reduction in tumor size than did either treatment with XL184 or PDT with BPD alone.

The targeted particles with the passports shrank tumors by 25 % in a single day, while nanoparticles with the antibodies but without the peptide passports had no effect on the tumor size.

A pre-surgery tumor size of greater than three centimeters was associated with worse LC, but local recurrence was not significantly affected by the number of brain metastases or the patients» histology or graded prognosis assessments.

«Tumor size is defining factor to response from promising melanoma drug.»

In terms of non-treatment factors, only tumor size impacted LC, as determined by multivariate Cox regression analysis.

«This was the first robust assessment to determine the impact of baseline tumor size on clinical endpoints in patients with metastatic melanoma — in particular — those receiving MK - 3475.

Patients were stratified by number of brain metastases (1 vs. 2 - 3), primary cancer type (melanoma vs. other histology) and pre-operative tumor size (less than vs. greater than three centimeters).

After two injections, cancer cells were depleted 100-fold from tumors the size of a dime, and tumors regressed 80 percent in size.

While transplantation of T cells alone had only little impact on tumor size in cancerous mice, the researchers achieved substantial regression of the cancer by transplanting both T cells and activated eosinophils.

«Our study aimed to compare contrast - enhanced mammography with breast MRI in evaluating residual breast cancer in patients undergoing presurgical systemic treatment to shrink their tumor size,» says Bhavika Patel, M.D., a radiologist at Mayo Clinic's Arizona campus.

Although hormone therapy alone will not cure prostate cancer, lowering androgen levels can reduce prostate tumors size or stall their growth.

Surgeons at the City of Hope Medical Center cut a tumor the size of a tennis ball out of the left side of Heil's brain.

While single - agent treatment with either drug had limited effects against mesothelioma, treatment with both drugs significantly reduced tumor size and prolonged the animals» survival.

Primary tumor size was measured by weight, and the number of metastases was determined by counting lung metastatic lesions.

Female mice carrying the MMTV - PyMT transgene that are either Postn + / + or Postn − / − will be examined for changes in primary tumor size and the number of spontaneously formed pulmonary macrometastases, which is a replication of the experiment reported in Figures 3A, 3B, and Supplemental Figure 13.

The importance of stromal POSTN was also demonstrated in another study in which orthotopic inoculation of gastric cancer cells into Rag2 − / −; Postn − / − mice reduced tumor size, decreased invasiveness, and decreased growth compared to Rag2 − / −; Postn + / + mice (Kikuchi et al., 2014).

The main established prognostic factors are tumor size and differentiation grade, spreading to armpit lymph nodes, hormone receptor status and HER2 - positivity.

In similar patients enrolled in a previous national trial, tumor size decreased in only 40 percent of patients treated with the same drugs but without hu14.18 K322A.

The decreased tumor size and enhanced tumor rejection in DGKζ - deficient mice indirectly suggests that enhanced Erk signaling may be superior to enhanced NF - κΒ activation in facilitating T cell activity against tumor, especially because DKO mice did not exhibit improved tumor control relative to DGKζ − / − mice.

To assess whether changes in T cell numbers within the tumors could be responsible for the observed differences in tumor size, we processed the spleen and tumors from mice and calculated percentages of CD4 + and CD8 + T cells.

Tumor sizes decreased in the treated mice, areas of cell death were visible, and all AAV2 treated mice survived through the study, a direct contrast to the untreated mice.

City of Hope is a leader in image - driven radiation planning, using advanced imaging technologies — such as computed tomography, magnetic resonance imaging and positron emission tomography scans — to determine tumor size and location and «sculpt» radiation delivery to the cancerous areas.

Excitingly, assessment of tumor size demonstrated an inhibitory effect of CD40L - expressing iPS - EPCs, while survival was also significantly prolonged.

Salk scientists found that the diabetes drug phenformin was effective at reducing tumor size in mice with lung cancer.

The objective was further explore and analyze the impact on prognosis of tumor size and of the different T descriptors; the prognostic significance of tumor burden in hilar and mediastinal lymph nodes; and the confirmation of the revised M1 categories (M1a and M1b) of the seventh edition of the classification along with the prognostic impact of number and anatomic location of metastases.

The morphological assessment of the differentiation degree in breast cancer has been provided useful prognostic information and the histological grade forms part of the multifactor Nottingham prognostic index together with tumor size and lymph node stage, which is used to assure individual patient for proper therapy [17].

The routine prognostic parameters revealed that the tumor size ranged between 2 - 5 cm in 67 % of GII, 58 % of GIII malignant cases and 70 % of the benign cases.

Age, tumor size, tumor site, LNM, VI and HER2 / neu immunopositive stain as well as the immunostaining of ER and PR for the malignant group were obtained from the Pathology Department, MRI.

«Our anaylsis suggests that biomarkers like E-cadherin are even more important than tumor size, tumor grade, the presence of estrogen receptors or the age of the patient.»

Tumor size in mice, left to right, with treatment with saline, just Dox, Gelipo - Dox, and Gelipo - TRAIL - Dox

The primary analysis focused on those who underwent SABR or thoracoscopic sublobar resection (wedge or segmental resections) for a tumor sized ≤ 2 cm.

In some of the children, the drugs blocked tumor growth; in others, they reduced tumor size.

Tumor size, histological type, and grade were significantly different between the groups.

«Determining prognosis involves a range of other clinical factors, including tumor size and grade, the degree to which the cancer has spread, and the age and race of the patient.

«Instead of just monitoring changes in tumor size, we can watch the perfusion of a contrast agent as it moves toward, around and through a tumor,» Vannier said.