[C and F] Total brain and
meningeal T cells (CD4 plus CD8), indicators of brain region inflammation, are reported for Type III - and attenuated Type I - infected animals.
Kipnis and his colleagues had previously shown that a type of white blood cell called a
T cell (shown above) in the meninges is associated with significant influence on cognition and hence were curious about the role of
meningeal immunity on brain function.