The authors report the results of a phase IIa immunotherapy trial of AN1792 (QS - 21) in patients with mild to moderate Alzheimer disease (AD) that was interrupted because
of meningoencephalitis in 6 % of immunized patients.
Levine, J.M., Fosgate, G.T., Porter, B., et al. «Epidemiology of Necrotizing
Meningoencephalitis in Pug Dogs.»
Pugs can also suffer from a chronic form of
granulomatous meningoencephalitis (an inflammation of the brain) specific to the breed called Pug Dog Encephalitis (PDE).
RESULTS: Symptoms and laboratory findings consistent
with meningoencephalitis occurred in 18 of 298 (6 %) patients treated with AN1792 compared with 0 of 74 on placebo (p = 0.020).
Health officials in North Carolina report that Lauren Seitz, an 18 - year - old Ohio woman who died on Sunday after a rafting trip with her church earlier this month, had contracted primary
amebic meningoencephalitis (PAM).
Interestingly, Dr. Rau's investigations have also confirmed that certain vaccines, including those for hepatitis B, the flu and tick -
borne meningoencephalitis, are co-factors in the development of this disease.
BACKGROUND: In a phase 2a clinical trial of AN1792 (Study 201), a potential immunotherapeutic agent for use in Alzheimer's disease (AD), approximately 6 % of the treated AD patients (18/300)
developed meningoencephalitis (ME).
Infections of poultry by flaviviruses are not uncommon, such as West Nile virus [15], [16] and Israel
turkey meningoencephalitis virus in geese and turkeys [17].
There are many diseases spread by fleas and ticks including Ehrlichiosis, dermatitis, Bartonellosis, Lyme disease, tapeworm infestation, Rickettsiae, and
even meningoencephalitis.
Chronic and recurrent infections of the inner and middle ear Overzealous cleaning of the ears Trauma from head injury Stroke Tumors
Polyps Meningoencephalitis Hypothyroidism Drugs like the aminoglycoside antibiotics, including amikacin, gentamicin, neomycin and tobramycin.
Some of the other health conditions that are common in Dachshunds include
granulomatous meningoencephalitis, epilepsy, thyroid problems, autoimmune disorders, and allergies.
Ticks can transmit diseases such as Lyme disease, Rocky Mountain spotted fever and tick -
borne meningoencephalitis, just to name a few.
Mice were infected with the aneuploid strains via intranasal instillation and monitored for signs of pulmonary cryptococcosis or
meningoencephalitis.
It causes more than 600,000 deaths a year from cryptococcal pneumonia and
meningoencephalitis, accounting for a third of all AIDS - related deaths.
[13] AN1792 was an active vaccine, with Aβ aggregates as the antigen, and
the meningoencephalitis is postulated to have been the result of the vaccine having roused a T - cell response against Aβ along with the necessary B - cell response, leading to a Th1 - biased inflammatory attack centralized on sites in the brain with local Aβ deposits.
Progress in the active immunotherapeutic approach to Alzheimer's disease: clinical investigations into AN1792 - associated
meningoencephalitis.
Particular effort was made to monitor subjects for signs of autoimmunity, and reassuringly none was observed; in particular, there was no sign of either treatment - associated autoimmunity or
meningoencephalitis.
ZIKV has been proven to cause serious birth defects, and is also being investigated for associations with other neurological conditions including Guillain - Barré Syndrome (GBS) and
meningoencephalitis.
In some cases, granulocytic
meningoencephalitis may be a precursor to cancer.
The direct cause of granulocytic
meningoencephalitis is unknown.
After coming to SNORT, Angie was diagnosed with a brain disease known as GME (Granulomatous
meningoencephalitis), which is an inflammatory autoimmune disease of the central nervous system.
Your veterinarian will check your dogs mental condition and nerves around the neck and head to see if there is a problem with the central nervous system or the virus that causes brain swelling (
meningoencephalitis).
There is also the danger of necrotizing
meningoencephalitis.