Circulating testosterone levels decline with increasing age but do not appear to be significantly affected by the
menopausal transition.8 As early as the 1940s, testosterone was reported not only to alleviate
menopausal symptoms but also to restore libido.9 In recent
years, evidence has accumulated supporting the hypothesis that the decline in endogenous testosterone levels is associated with
menopausal symptoms, including decreased libido, worse moods, and poorer quality of life.10 Clinical trials have demonstrated that exogenous androgens in conjunction with estrogens can ameliorate symptoms affecting sexual function and general well - being.11, 12 In addition, studies have found beneficial effects of androgen therapy on bone mineral density.13 - 15