Sentences with phrase «mesenchymal stem cells in»

Christopher J. Centeno, MD is an international expert and specialist in regenerative medicine and the clinical use of mesenchymal stem cells in orthopedics.

Therapeutic Application of Mesenchymal Stem Cells in Orthopaedics (April, 2005) in Pathologie Biologie.

Clinical Applications of Mesenchymal Stem Cells in Chronic Diseases (30 April 2014) in Stem Cells International.

Bone Marrow — Derived Mesenchymal Stem Cells in Repair of the Injured Lung (October, 2004) in American Journal of Respiratory Cell and Molecular Biology.

Mesenchymal Stem Cells in Arthritic Diseases (October 10, 2008) in Arthritis Research & Therapy.

European Heart Journal, 33 (5), 564 - 566, from http://eurheartj.oxfordjournals.org/content/early/2011/10/20/eurheartj.ehr385.full Clinical Applications of Mesenchymal Stem Cells in Chronic Diseases (30 April 2014) in Stem Cells International.

Mesenchymal stem cells in musculoskeletal tissue engineering: A review of recent advances in National University of Singapore.

Devine SM, Hoffman R. Role of mesenchymal stem cells in hematopoietic stem cell transplantation.

Tan J, Wu W, Xu X, Liao L, Zheng F, Messinger S, Sun X, Chen J, Yang S, Cai J, Gao X, Pileggi A, Ricordi C. Induction therapy with autologous mesenchymal stem cells in living - related kidney transplants: a randomized controlled trial.

So to understand what distinguishes mesenchymal stem cells in the gingiva from those in the skin, the Penn - led team began by comparing these extracellular vesicles between the two types.

They also summarise the outcome of clinical trials that have investigated the use of mesenchymal stem cells in the treatment of a number of inflammatory, degenerative and immune - mediated diseases of cats.

Not exact matches

Then, to boost the number of cells, which is another hurdle in tissue engineering, the researchers mixed the chondrocytes with human mesenchymal stem cells from bone marrow.

The scientists suspected that the lost enzyme might affect the animals» mesenchymal stem cells (MSCs)-- stem cells found in the bone marrow that are capable of developing into both the bone cells and fat cells that make up our skeletons.

And while cytochalasin D might not be the actual agent scientists use to trigger bone formation in the clinic, Rubin's study shows that triggering actin transport into the nuclei of cells may be a good way to force mesenchymal stem cells to become bone cells.

The granulomas were in fact being guarded by mesenchymal stem cells (MSCs), which normally form fat and bone (Proceedings of the National Academy of Sciences, DOI: 10.1073 / pnas.1007967107).

Despite a lack of rigorous clinical trials to test safety or efficacy, a ban of the treatment by health authorities, and a lack of peer review by the scientific community, the privately funded Stamina Foundation has been using cultured mesenchymal stem cells that have been exposed to putative conditions that favour neuronal differentiation to treat different diseases in severely or terminally ill patients.

«Infusions of mesenchymal stem cells are not transplants in any way.

After a few days, cells from the bloodstream called mesenchymal stem cells begin to accumulate in the «putty».

Single Lgr5 stem cells build crypt - villus structures in vitro without a mesenchymal niche.

The authors conclude that mesenchymal stem cell therapy has great potential as a therapeutic option in feline disease, but that many questions about the logistics of its use remain to be answered.

The present and potential clinical applications of mesenchymal stem cell therapy in cats are explored in a state - of - the - art review article published this month in the Journal of Feline Medicine and Surgery.

A group of researchers led by Kosuke Fujita, Visiting Researcher and Akito Maeda, Specially Appointed Professor at the HP Skin Regeneration, PIAS Collaborative Research, Osaka University clarified that cinnamtannin B - 1, or vegetable - based polyphenol, promotes the migration of Mesenchymal Stem Cells (MSCs) in blood circulation and accumulates them in damaged tissues (Fig. 1) to improve wound healing.

By the 1970s researchers had recognized another type of progenitor cell in the adult bone marrow, which they named the mesenchymal stem cell.

It turns out, for example, that mesenchymal stem cells do not regenerate tissue in isolation.

Studies in animals suggest that mesenchymal stem cells play important roles in the body's ability to heal after an injury, although researchers are still working out the signals and steps required to steer their differentiation into one type of tissue or another.

In the study, the protein Miro1 was shown to regulate the transfer of mitochondria from mesenchymal stem cells to epithelial cells.

«The introduction of mitochondria into damaged cells has beneficial effects on the health of cells and, in the long term, we believe that mesenchymal stem cells could even be engineered to create more effective therapies for lung disease in humans.»

«Conversely, the necrotic part of the tumor is driven by a distinct set of glioma stem cells utilizing the BIM1 pathway and are characterized by a mesenchymal, inflammatory cell type dependent on glucose metabolism in the absence of oxygen.

Second, we discovered in 2009 that the gingiva contains mesenchymal stem cells and that they can do a lot of good therapeutically.

From earlier work by Shi's group and others, it was clear that mesenchymal stem cells perform many of their functions by releasing signaling molecules in extracellular vesicles.

The Monash Biomedicine Discovery Institute (BDI) scientists provided the experimental expertise to test Cynata Therapeutics» induced pluripotent stem cell - derived mesenchymal stem cells (MSCs) in a model of experimental asthma.

Read the full paper titled Intranasal administration of mesenchymoangioblast - derived mesenchymal stem cells abrogates airway fibrosis and airway hyperresponsiveness associated with chronic allergic airways disease published in the FASEB Journal.

So here we asked, How are the gingival mesenchymal stem cells releasing all of these materials, and are they accelerating wound healing in the mucosal tissues?»

Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast.

A Novel Role for CAMKK1 in the Regulation of the Mesenchymal Stem Cell Secretome.

Co-Inflammatory Roles of TGFß1 in the Presence of TNFa Drive a Pro-inflammatory Fate in Mesenchymal Stem Cells.

Functional mesenchymal stem cells derived from human induced pluripotent stem cells attenuate limb ischemia in mice.

A new study suggests that CAMKK1 overexpression in mesenchymal stem cells can potentiate cardiac repair via the modulation of secreted paracrine acting factors

In a new study, researchers use proteomic approaches to discover how mesenchymal stem cells - derived exosomes modulate angiogenesis

Sioud M, Mobergslien A, Boudabous A, Fløisand Y. Evidence for the involvement of galectin - 3 in mesenchymal stem cell suppression of allogeneic T - cell proliferation.

Perivascular cells, including pericytes in the smallest blood vessels (e.g., microvessels) and ARCs around larger ones, express mesenchymal stem cell markers and bear a multi-differentiation fate potential (differentiate into osteoblasts, chondrocytes, adipocytes, smooth muscle cells and myocytes) similar to that documented for MSCs in vitro.

Impact of bone marrow - derived mesenchymal stem cells on remodeling the lung injury induced by lipopolysaccharides in mice Mouchira M Mohi El - Din, Laila A Rashed, Mohi A Mahmoud Haridy, Atef Mohamed Khalil, Mohamed A Mohamed Albadry.

Mesenchymal stem cells derived from human gingiva are capable of immunomodulatory functions and ameliorate inflammation - related tissue destruction in experimental colitis.

In an effort to improve this, we employed an alginate encapsulation strategy for human mesenchymal stem cells (hMSCs) and attached them to the heart with a biocompatible PEG hydrogel patch in a rat MI modeIn an effort to improve this, we employed an alginate encapsulation strategy for human mesenchymal stem cells (hMSCs) and attached them to the heart with a biocompatible PEG hydrogel patch in a rat MI modein a rat MI model.

Review of «A Novel Role for CAMKK1 in the Regulation of the Mesenchymal Stem Cell Secretome» from STEM CELLS Translational Medicine by Stuart P. AtkiStem Cell Secretome» from STEM CELLS Translational Medicine by Stuart P. AtkiSTEM CELLS Translational Medicine by Stuart P. Atkinson

Lack of telomerase activity in human mesenchymal stem cells.

In our latest work, for example, we have found evidence of a potentially clinically useful connection of complement in mesenchymal stem cell - based therapies, suggesting that complement is a valid target for improving the viability and function of mesenchymal stem cells, which are under extensive evaluation in clinical trials for treating many inflammatory and degenerative diseaseIn our latest work, for example, we have found evidence of a potentially clinically useful connection of complement in mesenchymal stem cell - based therapies, suggesting that complement is a valid target for improving the viability and function of mesenchymal stem cells, which are under extensive evaluation in clinical trials for treating many inflammatory and degenerative diseasein mesenchymal stem cell - based therapies, suggesting that complement is a valid target for improving the viability and function of mesenchymal stem cells, which are under extensive evaluation in clinical trials for treating many inflammatory and degenerative diseasein clinical trials for treating many inflammatory and degenerative diseases.

Initial imaging analysis of fluorescently labelled human iPSC - derived hepatic endoderm cells, umbilical cord - derived endothelial cells (HUVECs), and mesenchymal stem cells (MSCs) co-cultured in a solidified matrix gel to promote 3D growth found that the different cells collectively and automatically «condensed» into a multicellular central unit.

Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals.

Cell contact, prostaglandin E (2) and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4 + CD25 (High) forkhead box P3 + regulatory T cells.Clin Exp Immunol 2009; 156: 149 - Cell contact, prostaglandin E (2) and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4 + CD25 (High) forkhead box P3 + regulatory T cells.Clin Exp Immunol 2009; 156: 149 - cell induction of CD4 + CD25 (High) forkhead box P3 + regulatory T cells.Clin Exp Immunol 2009; 156: 149 - 160.