Sentences with phrase «messenger molecule»

Leptin is a messenger molecule that plays a highly significant role in how you lose fat.

Results have shown that the co-delivery of an anti-cancer drug (paclitaxel) with a highly potent anti-tumor «messenger molecule» (IL - 12 encoded plasmid2) using the carrier suppressed cancer growth more efficiently than the delivery of either paclitaxel or the plasmid in mice bearing 4T1 breast cancer.

Via an intermediate messenger molecule called RNA.

Drug - makers can build designer molecules with a sequence that will stick to the messenger molecule of the huntingtin gene, but not to other messengers.

The reasons include: depletion of the messenger molecule nitric oxide, lysis of red blood cells and alterations in the remaining cellsâ $ ™ stiffness.

Sildenafil, the active ingredient in Viagra, is known to inhibit the degradation of cyclic guanosine monophosphate (cGMP), a messenger molecule that advances the body clock in response to light.

The current study revealed that amlexanox exerts its effects through a specialized type of fat cell by increasing the level of a second messenger molecule called cAMP.

(RNA is typically thought of as the intermediary messenger molecule that helps make proteins, but ENCODE showed that much of RNA is an end product and is not used to make proteins.)

In earlier work, these investigators showed — as numerous others had done — that the messenger molecule, cyclic - di - GMP (c - di - GMP) promotes biofilm formation when such surfaces are present, said principal investigator Vincent T. Lee, Associate Professor, Department of Cell Biology and Molecular Genetics, University of Maryland, College Park.

In their recent publication in eLife, the Schwalbe group and their collaborators released molecular structures of the xpt - pbuX riboswitch in the off - position after synthesis and in the on - position upon binding by the small messenger molecule guanine.

A riboswitch is a short piece of RNA that can fold into different structures, depending on whether or not a small messenger molecule is binds to it.

This study could help us understand how changing messenger molecule tails could control gene expression in the context of regeneration.

The team found that the compounds prevent macrophages from producing messenger molecules called cytokines, which drive inflammation.

Variability in the tail — in length or in their position, affects the function of the messenger molecules, and hence influences gene expression.

Patterson, one of the few scientists who began studying the role of immune molecules in neurons before Shatz, has long focused on cytokines, messenger molecules that regulate inflammation in the body and (as Patterson eventually discovered) act as growth factors in the developing brain.

Now, a team of scientists from the Institute for Stem Cell Biology and Regenerative Medicine (inStem) and the National Centre for Biological Sciences (NCBS) have found that many messenger molecules in the flatworm Schmidtea mediterranea have alternate forms that vary in the lengths and positions of their tails.

Immune messenger molecules called cytokines and certain types of immune cells race to the bite site, making it inhospitable for the parasite.

In one experiment, the researchers confirmed previous observations that moving fluids can repress quorum sensing by carrying away messenger molecules.

The two systems differ in directness, but some messenger molecules are common to both

Neurologists had previously discussed a connection between the two disorders, because both involve an inadequate production of the neurotransmitter acetylcholine, one of the brains messenger molecules.

The cells then produce more of what the genes code for: cytokines, which are messenger molecules that circulate in the blood and activate immune cells.

Aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and indomethacin work by inhibiting an enzyme that produces prostaglandins — hormone - like messenger molecules that trigger many processes in the body, including inflammation.

Journal coverage includes basic signaling interests (e.g. neurotransmitters, ions and ion channels, receptors and messenger molecules, and kinases / phosphatases), as well as electrical signaling, signaling in neural circuits, neuroimaging, signaling aspects of pathologies, synaptic transmission and plasticity, and therapeutic intervention.

He feels that sleeping clears away the information signals that build up in our brain during the day as our nerve cells fire away and buildup messenger molecules that carry information.

Ozone stimulates the white blood cells to produce immune - related messenger molecules called cytokines.

Cell membranes are almost entirely composed of lipids and are responsible for protecting the cell from free radicals, letting nutrients in and wastes out, and receiving instructions from messenger molecules that tell the cell which activities it should perform.

Histamines are important neurotransmitter and immune messenger molecules.

Neurotransmitters are the messenger molecules between neuron cells, and their health and abundance is a central focus in our experiment with dreaming and food.

Not exact matches

Arctic apples don't brown because they make a special type of RNA molecule, which act as the messengers inside living cells, doling out instructions.

Soon, his team hopes to start enrolling these children in a pioneering clinical trial that delivers «messenger RNAs» — the molecules that normally carry instructions from a cell's DNA to its proteinmaking machinery.

Every tissue in an organism contains a variety of messenger RNA molecules, single - stranded nucleotide sequences bearing instructions for the making of specific proteins.

They all use RNA molecules as messengers to transfer the information from DNA to cellular factories called ribosomes, which then build proteins, which in turn drive our metabolisms and form the structures of our cells.

When it is active, each gene produces a unique molecule called a messenger ribonucleic acid, or mRNA.

The TTP / miR -9 pair functions as a switch limiting unscheduled accumulation of neuronal messengers in non-neuronal cells and ensuring coordinated accumulation of these molecules in neurons.

This marks the second time in four years that the chemistry Nobel has been awarded to someone working with x-ray crystallography; in 2006 Roger Kornberg took the prize for detailing the structure of messenger RNA, which is the molecule that carries the information the ribosome uses to build proteins, such as insulin or hemoglobin.

Moderna was founded on the idea that messenger RNA (mRNA), the molecule that relays genetic instructions from DNA to the cell's proteinmaking machinery, could be re-engineered into a versatile set of drugs and vaccines.

Plants grown from these cells make abnormal versions of messenger RNA, the molecule used to make the proteins.

Many researchers who once focused on messenger RNA and other relatively large RNA molecules have in the past 5 years turned their attention to these smaller cousins, including microRNA and small nuclear RNA.

MicroRNAs are short RNA molecules that typically bind to complementary sequences in messenger RNAs, thereby controlling the amounts of specific proteins produced by cells.

The same agents that damage DNA also damage its sister molecule messenger RNA (mRNA), which ferries transcripts of the genes to the tens of thousands of ribosomes in each cell.

Some scientists found that the fields make cells divide more rapidly or produce abnormally large quantities of messenger RNAs — molecules which are the intermediate step between genes and proteins.

Molecules that bind with specific messenger RNA's can selectively turn off genes.

They then purified messenger RNA — a molecule that plays a key role in the production of proteins — from the cells in the animals» upper intestines, injected the mRNA into immature eggs cells, and looked for changes in iron uptake.

First, it is a quality control mechanism used by cells to eliminate faulty messenger RNA (mRNA)-- molecules that are essential for transcribing genetic information into the construction of proteins critical for life.

When a cell needs a particular protein, it first transcribes the appropriate gene into a tightly edited molecule of pure information called messenger RNA.

In the affected children, the inability to remove the ubiquitin proteins from various molecules resulted in an increased production of chemical messengers that lead to inflammation (inflammatory cytokines).

Snippets of RNA known as short interfering RNA (siRNA) turn off specific genes inside living cells by destroying the messenger RNA molecules that carry DNA's instructions to the rest of the cell.

The idea of using messenger RNA molecules as vaccines has been around for about 30 years, but one of the major obstacles has been finding a safe and effective way to deliver them.

The conventional view is that the main function of RNA is to convey instructions from DNA to the protein - making factories in cells — a task carried out by large molecules of «messenger» RNA.

The middle layer reveals an abundance of messenger RNA molecules (white dots) for the gene encoding hepcidin, the iron - regulating hormone.