Sentences with phrase «metabolic abnormalities in»

In some people, they're related to metabolic abnormalities in other parts of the body, some of which stem from chronically high insulin.

«Use of P - 31 magnetic resonance spectroscopy to detect metabolic abnormalities in muscles of patients with fibromyalgia.»

Importantly, NAFLD is associated with visceral adiposity and other metabolic abnormalities in HIV,» the authors write.

«In young and middle - aged adults, our findings suggest that early detection and treatment of mild - to - moderate sleep apnea is warranted in order to prevent future cardiometabolic disease,» said lead author and postdoctoral scholar Yun Li, MD. «Given the stronger association of sleep apnea with metabolic abnormalities in this age group, emphasis should be placed on yearly monitoring of indices of metabolic symptoms and lifestyle interventions, such as weight control, healthy diet, regular exercise, and stress management.»

However, investigating metabolic abnormalities in the brain has been hindered by lack of a good imaging tools.

And there have been some preliminary studies with obsessive - compulsive neurosis where you can see a metabolic abnormality in the caudate nucleus in imaging.

Not exact matches

A research finding in January 2017 reveal that Golden Rice hybrid with Swarna variety resulted to phenotyphic abnormalities, stunted growth and low yield, virtually adulterating the metabolic and genetic traits of the variety.

The expert team in the Division of Pediatric Nephrology at Floating Hospital for Children provides comprehensive evaluation and treatment for the range of metabolic abnormalities.

Besides getting fatter, we are also developing more metabolic disorders, such as type 2 diabetes, which is marked by hormonal abnormalities in the processing and storage of nutrients and is far more common in obese individuals than in lean ones.

«We now have a really good picture of this abnormality in mice, and we suspect it is very similar in humans,» said Fuming Zhang, a research professor in the laboratory of Robert J. Linhardt, the Ann and John H. Broadbent Jr»59 Senior Constellation Professor of Biocatalysis and Metabolic Engineering, and a member of the Center for Biotechnology and Interdisciplinary Studies at Rensselaer.

A person meets the criteria of the metabolic syndrome if they have three or more of the following metabolic abnormalities: blood pressure at 130/85 mm Hg or above; fasting glucose of 100 mg / dL or higher; waist circumference 40 inches or more in men and 35 inches in women; triglyceride levels at 150 mg / dL or more, and high - density lipoprotein cholesterol (HDL - C) greater than 40 mg / dL in men and 50 in women.

Metabolic syndrome, a cluster of cardiometabolic conditions, may be a biological mechanism linking posttraumatic stress disorder (PTSD) to structural brain abnormalities, according to a new study in Biological Psychiatry.

The new study by NYU Langone Medical Center researchers reveals that mice given lifelong low doses of penicillin starting in the last week of pregnancy or during nursing were more susceptible to obesity and metabolic abnormalities than mice exposed to the antibiotic later in life.

Mice lacking insulin receptor in brain or on hypothalamic neurons display an array of metabolic abnormalities, however, the role of insulin action on astrocytes and neurobehaviors remains less well - studied.

Nevertheless, the balance of sex hormones appears important as inappropriate low testosterone, or high estrogen concentrations in males, may also relate to fatty liver disease and metabolic abnormalities.

Females may exert a higher capacity for adipocyte enlargement and adipose tissue plasticity may play a role in obesity - related metabolic abnormalities and ectopic fat deposition (237).

It is unfortunate that the investigators did not assess insulin secretion, insulin action, or systemic inflammation in early - aging BubR1H / H; INK - ATTAC mice, with and without ablation of senescent adipose cells, but reasonable to be optimistic that doing so would yield some normalization of age - related metabolic abnormalities.

These findings are consistent with metabolic or microstructural abnormalities in bipolar disorder and draw attention to roles of the cerebral white matter and cerebellum.

These age - related abnormalities then drive a range of unhealthy metabolic changes, including a reduced ability to move blood sugar out of the blood in response to the hormone insulin.

Studies show that the mangiferin in mangoes can improve metabolic abnormalities and soothe metabolic disorders.

Roland Rosmond, Mary F. Dallman and Per Björntorp, Stress - Related Cortisol Secretion in Men: Relationships with Abdominal Obesity and Endocrine, Metabolic and Hemodynamic Abnormalities, The Journal of Clinical Endocrinology & Metabolism, 1998, Vol.

Exercise also leads to reduced inflammation, lower blood sugar levels and improvements in all the other metabolic abnormalities that are associated with excess abdominal fat (36).

Develop as a result of lifestyle - sex, age, alcohol consumption, smoking and common metabolic abnormalities (hyperlactemia which is an Increased level of lactate — A salt or ester of lactic acid in the blood — without evidence of lactic acidosis or shock, hemochromatosis which is an iron metabolism disorder, Acid Lipase Disease — an inability to breakdown fats and as a result fats build up in the cells of the body — is a lipid metabolism disorder

«A prominent and well - characterized feature of AD is progressive, region - specific declines in the cerebral metabolic rate of glucose (CMRglc)-LSB-...] Carriers of a common Alzheimer's susceptibility gene [APOE Ɛ4] have functional brain abnormalities in young adulthood, several decades before possible onset of dementia.

Stress - Related Cortisol Secretion in Men: Relationships with Abdominal Obesity and Endocrine, Metabolic and Hemodynamic Abnormalities Roland Rosmond, Mary F. Dallman, and Per Bjorntorp J. Clin.

Reversal of behavioral and metabolic abnormalities, and insulin resistance syndrome, by dietary restriction in mice deficient in brain - derived neurotrophic factor

Higher cardiovascular disease risk, blood lipid abnormalities, hypertension in men, cardiac issues, and four times higher metabolic syndrome rates later in later life are all risks.

Identification and correction of these metabolic abnormalities, including leptin resistance and cellular thyroid dysfunction, can result in dramatic long term successful weight loss.

A person with insulin resistance will divert a greater proportion of dietary carbohydrate to the liver where much of it is converted to fat (that is, de novo lipogenesis), as opposed to being oxidized for energy in skeletal muscle.30 Although Hellerstein31 has recently reported that de novo lipogenesis contributes only ∼ 20 % of new triglycerides, this greater conversion of dietary carbohydrate into fat, much of it entering the circulation as saturated fat, is a metabolic abnormality that significantly increases risk for diabetes and heart disease.

We also know that high testosterone in pregnancy cause gut microbiota changes in the offspring that are characteristic of the metabolic abnormalities found in PCOS.

In the initial report, mice harboring a mutation in the core circadian gene Clock (termed Clock mutant mice) were fed a high - fat (HF) diet and observed to develop obesity at a young age, as well as a variety of metabolic and endocrine abnormalities consistent with the metabolic syndrome (2In the initial report, mice harboring a mutation in the core circadian gene Clock (termed Clock mutant mice) were fed a high - fat (HF) diet and observed to develop obesity at a young age, as well as a variety of metabolic and endocrine abnormalities consistent with the metabolic syndrome (2in the core circadian gene Clock (termed Clock mutant mice) were fed a high - fat (HF) diet and observed to develop obesity at a young age, as well as a variety of metabolic and endocrine abnormalities consistent with the metabolic syndrome (2).

They have been linked to human health issues related to sperm quality, fertility, abnormalities in sex organs, endometriosis, early puberty, nervous system function, immune function, cancers, breathing problems, metabolic issues, obesity, heart health, growth, neurological and learning disabilities, and more.

Participants were excluded for the following: BMI > 30 kg / m2, metabolic disease, low hematocrit or hemoglobin, vascular disease, hypertension, cardiac abnormalities, renal disease, recent weight loss or gain, participation in a weight - loss diet / exercise program, smoking, and anabolic steroid usage.

First noticed in dogs some 75 years ago, vitamin deficiencies can lead to widely ranging clinical abnormalities that reflect the diversity of their metabolic roles.

While fats are initially beneficial energy sources, lipid waste products (ketone bodies) accumulate in the blood and invoke severe and potentially life - threatening metabolic abnormalities.

With few exceptions, regardless of the many different presentations of chronic heart disease in dogs and cats, whether primarily or secondarily, there are metabolic and structural abnormalities at the level of the heart muscle.

Studies in dogs indicate that the parenteral administration of a single dose of cyanocobalamin (250 - 500 µg SQ once per month) is enough to prevent recurrence of metabolic abnormalities for up to one month.

In a study of humans, scientists connected an increased risk of metabolic abnormalities like diabetes and metabolic syndrome with low serum amylase levels.

In such cases, if the diarrhea becomes very frequent or very profuse or both, then metabolic abnormalities may ensue.

The similar responses in echinoplutei across regions, including smaller arms, changes in morphometry and increased abnormality and mortality are likely owing to the interactive effects of this metabolic stressor (hypercapnia) and the toxic effects of acidification on regulation of development and body patterning.

First, depression has been linked to multiple biological abnormalities, including vascular pathologic changes, autonomic function changes, hypercoagulability, and hypothalamic - pituitary - adrenal axis hyperactivity.10 Evidence shows that depression in adulthood is linked to elevated risk of developing cardiovascular disease, diabetes, and dementia in later life.11 Second, inflammation contributes to atherosclerosis, insulin resistance, and neurodegeneration.12 - 14 Evidence shows that elevation in inflammation biomarkers, such as C - reactive protein (CRP), in adulthood predicts the development of cardiovascular disease, diabetes, and dementia in later life.15 - 17 Third, metabolic abnormalities such as obesity, dyslipidemia, glucose intolerance, hypertension, and cardiorespiratory fitness contribute to vascular lesions and hormonal imbalance.

These abnormalities tend to cluster in the same individuals.18, 19 Evidence shows that the clustering of metabolic risk markers in adulthood is associated with elevated risk of developing cardiovascular disease, diabetes, and dementia in later life.18, 20 Importantly, depression, inflammation, and the clustering of metabolic risk markers frequently co-occur in the same individuals, and their co-occurrence is associated with the greatest disease risk.20, 21 To improve life quality in aging populations, it is critical to gain a better understanding of the origins of these 3 age - related - disease risks.

Objective To understand why children exposed to adverse psychosocial experiences are at elevated risk for age - related disease, such as cardiovascular disease, by testing whether adverse childhood experiences predict enduring abnormalities in stress - sensitive biological systems, namely, the nervous, immune, and endocrine / metabolic systems.