Sentences with phrase «metabolic alterations»
The term "metabolic alterations" refers to changes or disturbances in the chemical reactions and processes that occur within our body to convert food into energy. These alterations can affect how our bodies utilize nutrients, regulate sugar levels, and maintain overall balance, which might lead to various health conditions or imbalances in our body. Full definition
According to the study, these modifications specifically mark highly expressed genes and their presence changes upon metabolic alterations, for example upon fasting.
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Cancer cells undergo metabolic alterations to meet the increased energy demands that support their excess growth and survival.
His research interests center on identifying and understanding the mechanisms driving whole body metabolic alterations and tissue interactions in early disease states.
The most difficult challenge when feeding cancer patients is to provide balance between calories, essential nutrients, and fluids to avoid metabolic alterations due to a decrease in food consumption.
Most research on the mechanisms of TBI has focused on neurochemical changes at the site of injury, such as metabolic alterations and ion imbalances inside neurons, he says.
One is the nanoscale structural breakdown of RGCs, and the other is metabolic alterations associated with cell degeneration.
One of the key metabolic alterations that takes place during EMT is that of the epidermal growth factor receptor (EGFR) which is a pathway that regulates growth, survival, proliferation, and differentiation in mammalian cells.
He envisions a time, however, when bacteria will «breathe in hydrogen» produced by water splitting and ultimately use the hydrogen to produce desired products ranging from fuels to fertilizers, plastics and drugs, depending on the specific metabolic alterations designed for the bugs.
After implementing the mf - OCT using advanced optical engineering, we will conduct a pilot clinical studies to validate the nanoscale structures and the oxygen metabolic alterations are present in glaucoma patients and normal vision patients.
These are characterized by glycosuria (presence of glucose in the urine, which is normally glucose - free), polyuria (excessive production and passage of urine), polydipsia (excessive thirst) and polyfagia (excessive appetite), as well as by a number of serious metabolic alterations caused by the inability of body cells to take up and use blood glucose, which is the main fuel for the body in normal conditions.
When the rectal temperature drops below 94o F (34.4 o C), the accompanying metabolic alterations are life - threatening.
The work, now published in the journal Cancer Research, revealed that a metabolic alteration at the mitochondrial level derived from VEGF's action is involved in chemotherapy resistance.
To do this, they infected human malignant glioblastoma cells with Zika and recorded microscope images of them 24 hours and 48 hours after infection in order to observe any metabolic alterations (cytopathic effects) caused by inoculation of the virus.
Her research interest lies in metabolic alterations that arise in cancer.
Can we therapeutically target the metabolic alterations in cancer cells?
Moreover, metabolic reprogramming is a common hallmark in cancer, and emerging evidence suggests that a metabolic alteration may also be present in early glaucoma, including a change of oxygen consumption in glaucomatous retina.
Tumor cells constantly alter their metabolic state in response to oncogenic stimuli, nutrient availability, and interaction with immune cells however the precise regulation that precedes the metabolic alteration is poorly understood.
This leads to a whole host of problems, including feeling sluggish, depressed, moody, loss of muscle mass, water retention, metabolic alterations and a generally feeling of «not wanting to diet or exercise anymore».
«Our results demonstrate that metabolic alterations may precede the development of small intestinal villous atrophy and provide a further rationale for early institution of GFD [gluten - free diet] in patients with potential CD [celiac disease],» the study concluded.
Even though plasma zinc is an acute phase reactant that may change in response to metabolic alterations, plasma zinc levels react to dietary intake in a rapid and measurable manner (Gershwin et al. 1985, Keen 1990).
These metabolic alterations include the inability of normal tissues to take up blood glucose because of their decreased sensitivity or decreased responsiveness to insulin; an increased protein degradation combined with a decreased protein synthesis; finally an increased activity of the enzymes involved in degradation and mobilization of lipids in body fat cells.
The need for an early nutritional support can be explained by the fact that the metabolic alterations responsible for the development of cancer cachexia are usually present in cancer patients long before clinical signs of cachexia become apparent.