Sentences with phrase «metabolic disease studies»
Further describing these findings, the following information shows why these cells are ideal for metabolic disease studies.
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Data from a number of other studies, including the Nurses» Health Study and the Health Professionals Follow - up Study also report greater risk of type 2 diabetes, high blood pressure, heart disease and metabolic syndrome, which is related to diabetes and cardiovascular problems, for consumers of artificially sweetened beverages.
«Our laboratory and clinical studies of alcoholics during the past several years have convinced us that alcoholism is a metabolic disease.»
«Taken together with previously established benefits of egg intake on HDL profiles, these findings further support the notion that eggs serve as a functional food to reduce cardiovascular disease risk in individuals with metabolic syndrome,» says Catherine Andersen, lead study author and PhD candidate at the University of Connecticut.
Additionally, there is evidence from longitudinal studies showing that increased egg consumption is associated with a lower risk of heart disease and metabolic disorders (8).
ST. LOUIS, Nov 14, 2011 — A study published online in Hormone and Metabolic Research showed the positive effects of soy protein isolate in obesity - related conditions such as inflammation and fatty liver disease.
The focus of her study is improving the nutrition strategies for transition cows that are more susceptible to disease and metabolic disorders such as ketosis.
Although the observational studies that underlie our models all adjusted for multiple confounders, including known risk factors for the disease outcomes of interest, risk factors for early breastfeeding cessation such as preterm birth, preeclampsia, and obesity are also risk factors for metabolic disease in later life.
Independent studies have conclusively shown adverse health effects of BPA on the brain and reproductive system, as well as metabolic diseases in laboratory animals.
Scientists have shifted from studying single molecules to investigating large complexes of interacting biological macromolecules involved in processes such as metabolic pathways, gene expression, and development of disease.
In research that has implications for diabetes and other metabolic diseases, an international study based at UT Southwestern Medical Center found that the protein connexin 43 (Cx43) forms cell - to - cell communication channels on the surface of emerging beige fat cells that amplify the signals from those few nerve fibers.
They also set reference points for future studies looking at the connection between metabolic processes and diseases such as cancer.»
«It seems to be real,» said Ronald Jandacek, a metabolic disease specialist at the University of Cincinnati who was not involved in the study.
A growing number of epidemiologic studies have suggested an association between sedentary behavior and chronic diseases including obesity, diabetes, insulin resistance, metabolic syndrome, cardiovascular disease, cancer, and even death that is distinct from those related to a lack of physical activity.
The studies not only point to the future possibility of specific microRNAs as a treatment for colorectal cancer, but also to the importance of external metabolic events conducted outside the cancer cell in the progression of the disease — factors that could someday be targeted to help slow metastasis, or even block it entirely.
Clinically, the genetic and trauma - caused conditions are very similar, with bone formation in muscle leading to pain and restricted movement, according to the leader of the new study, Edward Hsiao, MD, PhD, an endocrinologist who cares for patients with rare and unusual bone diseases at the UCSF Metabolic Bone Clinic in the Division of Endocrinology and Metabolism.
The study, published today in Science, uncovers the key role of the protein YME1 in the regulation of the number, type and shape of mitocondria, and demonstrates that its absence induces a metabolic defect typical of patients with heart disease.
«Our study suggests that short height in children is a possible marker of stroke risk and suggests these children should pay extra attention to changing or treating modifiable risk factors for stroke throughout life to reduce the chances of having this disease,» said senior study author Jennifer L. Baker, Ph.D., associate professor in the Center for Clinical Research and Prevention at Bispebjerg and Frederiksberg Hospital and Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, at the University of Copenhagen, in Denmark.
The study also shows that metabolic strategies based on diet are sufficient to restore correct heart function, opening the possibility of future treatments for patients with this disease.
«While [grizzly] bears were relatively resistant to developing severe metabolic imbalances or overt clinical disease due to a high saturated fat diet, it is important to note that this study occurred only over a single feeding season,» says Danielle Rivet, who led the study during her graduate studies at WSU.
«It's clear from these types of studies that the way we're keeping the lights on until late at night, the way in which society demands that we stay active for so much longer, could well be contributing to aspects of the metabolic disease we're seeing now,» says Steve Kay, a molecular geneticist at the University of California, San Diego.
Dr Simon Jones, Consultant in Paediatric Inherited Metabolic Disease at Saint Mary's Hospital, Manchester, who is leading the study explains: It's important for us to undertake research in rare diseases, like Sanfilippo Disease, so that we can provide these patients with the best possible care.
In a new study published in The American Journal of Medicine, researchers looked at the role metabolic syndrome and cardiovascular disease play in postmenopausal women's sexual health.
«Previous pilot studies researching the use of DBS in Alzheimer's have indicated the potential to slow cognitive decline in some patients, and have even shown metabolic changes in the brain that may slow the progression of the disease.»
The results of these two studies suggest that exposure to TF may promote the development of metabolic disease in humans.
In both human and laboratory studies, the offspring of mothers who are obese or consume a high - fat diet during pregnancy are much more likely to be overweight and have weight - related problems such as metabolic syndrome, diabetes and heart disease later in life.
That's the claim of a new study, which finds increases in metabolic disease and intestinal inflammation in mice fed two common emulsifiers used in processed food.
The study looked at a way to substitute animal - based saturated fats for plant - based unsaturated fats in muffins made for patients with the metabolic syndrome, a group of risk factors that affect about a third of adults in the United States, increasing their chance of cardiovascular disease and type 2 diabetes.
Dr Margaret O'Hara, from the Molecular Physics Group and primary investigator on the project, said: «Previous studies have found potential biomarkers for liver disease, such as isoprene and acetone, but they are not specific enough because they are possible biomarkers for other diseases or can arise from numerous normal metabolic processes.
«Sex reassignment surgery may be better for transgender women's health than hormones only: Study investigates metabolic disease risk after receiving only hormone therapy compared to surgery.»
Said Flask, «In this initial paper, we validated our new methodology, opening the possibility for numerous follow - on application studies in cancer, genetic diseases such as cystic fibrosis, and metabolic diseases such as diabetes.»
«Introducing brown fat is an exciting new approach to treating obesity and associated metabolic diseases, such as diabetes,» said study first author Baoming Nie, PhD, a former postdoctoral scholar at Gladstone.
The results of this original study are highly relevant to other human diseases that dependent on genome instability, such as fungal infection or cancer, and open new venues for anti-leishmanial drug discovery using host - directed strategies that target the parasite's metabolic dependence on the host cell, thus preventing the adaptive evolution of drug resistant parasites.
The studies performed were based on this idea that unique metabolic differences are associated with an illness or disease.
«It is becoming increasingly clear that the average person's fiber intake in a Western country has drastically reduced over the past few decades,» says Fredrik Bäckhed, who studies the role of the normal gut microbiota in metabolic diseases at the University of Gothenburg, Sweden and is a co-senior author of the other paper.
«Previous studies in mice have indicated that bacteria that are able to encroach upon the epithelium might be able to promote inflammation that drives metabolic diseases, and now we've shown that this is also a feature of metabolic disease in humans, specifically type 2 diabetics who are exhibiting microbiota encroachment.»
In humans, developing metabolic disease, particularly type 2 diabetes, is correlated with having bacteria that penetrate the mucus lining of the colon, according to a study led by Drs. Benoit Chassaing and Andrew Gewirtz at Georgia State University.
The study is one of the first to characterize the timing of exposure to such stress and the emergence of the physiologic changes leading to cardio - metabolic disease and to document these relationships during this critical developmental period.
«Although in our study we published the results obtained from these colorectal samples, we are also studying the relationship between this protein and diseases of the liver, the primary metabolic organ,» explains Djouder.
Among mechanically ventilated patients with chronic obstructive pulmonary disease (COPD) and metabolic alkalosis, administration of the respiratory stimulant acetazolamide did not significantly reduce the duration of invasive mechanical ventilation, according to a study in the February 2 issue of JAMA.
Waist circumference can indicate the amount of excess fat found around the abdomen and previous studies have shown excess abdominal fat may increase the risk of chronic system inflammation and metabolic diseases.
«We've known for a long time that exercise protects against metabolic and cardiovascular disease,» says Robert Gerszten, director of Translational Research in the Cardiology Division at Massachusetts General Hospital, and co-author of the new study.
In describing the public health implications of the study's main findings, co-author Charles Benbrook, a Visiting Scholar at the Bloomberg School of Public Health at Johns Hopkins University, points out that «The near - perfect balance of omega - 6 and omega - 3 fatty acids in grassmilk dairy products will help consumers looking for simple, lifestyle options to reduce the risk of cardiovascular and other metabolic diseases.»
«Previous studies have indicated that a mother's weight at conception is associated with increased risk of cardiovascular and metabolic diseases in the children later in life.
«Our studies indicate that DNA - PK is one of the drivers of the metabolic and fitness decline that occurs during aging, which makes staying lean and physically fit difficult and increases susceptibility to metabolic diseases like diabetes,» Chung said.
We'd recently published some high profile studies of AMD, cleft lip, metabolic syndromes, and other phenotypes that demonstrated our ability to unravel common complex disease.
Published in Kidney International, the study is distinctive in examining the metabolism of patients while they were still healthy or in very early stages of the disease, and in the breadth of metabolic factors analyzed, says lead author Monika Niewczas, M.D., Ph.D..
This model is particularly amenable to gene editing technology, which makes it possible to design cells with specific disease - relevant mutations — a boon for those studying the cause and progression of metabolic diseases of the liver.
However, a new study by Joslin Diabetes Center researchers that compares the metabolic fingerprints of patients who develop ESRD versus those who don't has furnished new clues to the disease.
As a result, we're seeing exome and genome sequencing studies published all over the place, not just in genetics / genomics journals but also many that focus on specific tissues (e.g. blood) or diseases (e.g. cancer, metabolic diseases, vision disorders, you name it).