Genetic modeling of estrogen
metabolism as a risk factor of hormone - dependent disorders.
Increased catechol estrogen
metabolism as a risk factor for nonfamilial breast cancer.
Not exact matches
Our diets can also change our
metabolism as well
as the levels of circulating
factors (hormones, lipids, etc.) which may be markers for disease
risk.
This laboratory studies aspects of one - carbon
metabolism, namely the micronutrients folate and vitamin B12, which serve
as substrate and cofactor, respectively, in the methionine cycle and homocysteine, which is a branch - point metabolite in the methionine cycle and an independent
risk factor for cardiovascular disease (coronary artery, cerebrovascular and peripheral vascular disease), cognitive impairment (Alzheimer's disease) and complications of pregnancy (neural tube defects).
May positively affect
risk factors such
as insulin resistance, metabolic rate, glucose
metabolism, blood pressure
15 In fact, type 2 diabetes (T2D)-- a condition stemming from broken glucose
metabolism and insulin signaling — has been identified
as an additional
risk factor for developing AD.16, 17 Moreover, the pathological changes that occur in AD in the brain physically resemble those seen in the pancreas and vasculature in T2D.9, 18 Type 2 diabetics who carry ApoE4 alleles are at the greatest
risk for AD, with an even more severe
risk reserved for those treated with exogenous insulin.19 This suggests that either T2D or related features of the metabolic syndrome bring about AD, or that they are separate consequences of the same underlying cause — and moreover, that insulin is a key
factor.
«Clinically and cognitively normal individuals with and without AD
risk factors, following dietary patterns characterized by high intakes of whole grains, fresh fruits, vegetables, legumes, fish, and low - fat dairy products (which provide higher intakes of vitamin B12, vitamin D, and n - 3 polyunsaturated fatty acids) and by low intakes of refined sugars, French fries, high - fat dairy products, butter, and processed meat, show lower accumulation of Aβ in the brain and higher cerebral glucose
metabolism,
as evidenced by neuroimaging analysis of gray matter volumes (a marker of brain atrophy), C - Pittsburgh compound B (to measure the accumulation of fibrillar Aβ), and F - fluorodeoxyglucose (to assess brain glucose
metabolism.»
Psychosocial problems, increased cardiovascular
risk factors, abnormal glucose
metabolism, hepatic gastrointestinal disturbances, sleep apnoea, orthopedic complications
as well
as poor self - esteem and body image.