MGmapper: Reference based mapping and taxonomy annotation of
metagenomics sequence reads — Thomas Petersen — May 2017
Not exact matches
Metagenomics poses many analysis challenges, from errors
reading DNA
sequences to decoding which
sequences come from which of the hundreds of microbial species in a microbiome sample.
We designed PhylOTU, the first computational tool for estimating the taxonomic composition of
metagenomic samples from short, next - generation
sequencing reads.
Genome
sequencing has become a powerful tool for studying emerging infectious diseases; however, genome
sequencing directly from clinical samples without isolation remains challenging for viruses such as Zika, where
metagenomic sequencing methods may generate insufficient numbers of viral
reads.