Not exact matches
Along the same lines, Daniel Sessler, an anesthesiologist at Cleveland Clinic
in Ohio, is leading two randomized trials looking at whether nerve blocks added to general anesthesia reduce
metastases in patients undergoing surgery to remove either breast or
lung cancer.
Many
lung cancer trials have traditionally excluded
patients with brain
metastases at baseline, expecting that the presence of
metastases would create negative results that could
in turn create the appearance of drug failure.
Research from McMaster University has identified new regulators of brain
metastases in patients with
lung cancer.
«If you look at a set of
lung cancer patients, like we did in the paper, who develop brain metastases, they all have those two genes in their primary lung cancer,» said Sheila Singh, the study's supervisor, associate professor at the Michael G. DeGroote School of Medicine, scientist with the Stem Cell and Cancer Research Institute at McMaster University and neurosurgeon at McMaster Children's Hos
cancer patients, like we did
in the paper, who develop brain
metastases, they all have those two genes
in their primary
lung cancer,» said Sheila Singh, the study's supervisor, associate professor at the Michael G. DeGroote School of Medicine, scientist with the Stem Cell and Cancer Research Institute at McMaster University and neurosurgeon at McMaster Children's Hos
cancer,» said Sheila Singh, the study's supervisor, associate professor at the Michael G. DeGroote School of Medicine, scientist with the Stem Cell and
Cancer Research Institute at McMaster University and neurosurgeon at McMaster Children's Hos
Cancer Research Institute at McMaster University and neurosurgeon at McMaster Children's Hospital.
«Rare mutation may extend survival
in lung cancer patients with brain
metastases.»
«
In cancer, it's usually the
metastases to the
lung, liver or brain that kill the
patient, but it's hard to get tissue safely from these areas,» said Rick Lanman, MD, Guardant Health's chief medical officer.
Of the colon
cancer patients that develop
metastases, 40 % present metastasis first to the liver and later to the
lung, always
in this clinical order of appearance.
Novel strategies that are effective
in treating brain
metastases in patients with
lung cancer are needed.
DENVER — Leptomeningeal
metastases (LM), a devastating complication and predictor of poor survival
in lung cancer patients, was found to be more prevalent
in non-small cell
lung cancer (NSCLC)
patients with epidermal growth factor receptor (EGFR) mutations.