Sentences with phrase «methylated cytosines»
Our first insight came from the characterisation of a mutation that disrupts the silencing property of methylated cytosines.
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They found that in the HSCs of healthy people, most DNA cytosines (one of four main components of DNA) are methylated.
Previous studies have shown that cytosine can exist in two forms, one of which is the methylated version methylcytosine.
CpG, regions of DNA in which a cytosine nucleotide occurs next to a guanine nucleotide separated by only one phosphate; TNF, Tumor necrosis factor; SES, socioeconomic status; DMR, Differentially methylated Region