Transposon element sites were far more likely to be
methylated than genes, which tended to be demethylated.
Not exact matches
In May researchers at McGill University reported that the
gene responsible for creating cells» protein - building machinery is more frequently
methylated in the hippocampus — the brain region responsible for short - term memory and spatial navigation — of depressed suicide victims who suffered child abuse
than in the brains of nonsuicide victims who were not abused.
The researchers found more
than 9000
genes that were either more or less likely to be
methylated depending on whether the subject was lean or obese.
Molecular profiling of large tumour numbers has also allowed the annotation of more
than 13 million non-coding mutations, 18 029
gene fusions, 187 429 genome rearrangements, 1 271 436 abnormal copy number segments, 9 175 462 abnormal expression variants and 7 879 142 differentially
methylated CpG dinucleotides.
Gene promoters more
methylated in CPA have higher CpG density
than the average CpG content of all promoters analyzed (p < 6.3E - 27).