Sentences with phrase «mice after transplantation»

Functional rescue of dopaminergic neuron loss in Parkinson's disease mice after transplantation of hematopoietic stem and progenitor cells.

Functional rescue of dopaminergic neuron loss in Parkinson's disease mice after transplantation of hematopoietic stem and progenitor cells, EBioMedicine, in press.

However, their initial finding demonstrated that progenitor derived from iPSCs generated using lentiviral gene transduction led to the high incidence of highly aggressive tumors in immunodeficient mice after transplantation under the kidney capsule.

Not exact matches

Previous studies in mice have shown, however, that even genetically identical iPS cells can trigger an immune response after transplantation.

The researchers then assessed the prevalence of a kind of immune cell called a myeloid cell, which were derived from the donated stem cells in the blood of the recipient mice, at eight and 16 weeks after transplantation.

Broadly suppressing the immune system after lung transplantation may inadvertently encourage organ rejection, according to a new study in mice.

«The studies clearly show that a high - fat diet with or without the genetic loss of ApoE can alter the immune response in mice after heart transplantation,» he continued.

Mice were on the high - fat or lower - fat diet for four weeks before transplantation and maintained on the same diet after transplantation.

Pretreating mice with STAR2 protected them from developing GvHD after immune cell transplantation.

Adenovirally generated induced pluripotent stem cells mediate a preservation of motor function or behavioral recovery after transplantation in a mouse model of Huntington's Disease

Spleen CD4 + T cells were harvested from mice 21 d after transplantation and cultured or not with VPA for 24 h. Western blot assay showed that VPA attenuated the phosphorylation level of Akt in a dose - dependent manner (Fig. 4F).

No leukemia growth was observed in mice receiving TCD - BM + spleen T cells, indicating a potent GVL effect, but these mice developed severe GVHD after transplantation (Fig. 5B — D).

Administration of VPA to mice reconstituted with TCD - BM only caused no mortality, and pathological analysis showed no evidence of GVHD 60 d after transplantation (data not show).

For Western blot assay and immunoprecipitation analysis, CD4 + T cells were isolated from mice spleen on day 21 after transplantation using a Mouse CD4 + T Cell Isolation Kit (Miltenyi Biotec), and the procedures were performed as described previously (35).

The color allows the scientists to track the stem cells inside the mouse brain after transplantation.

Interestingly, mice that had been treated with stem cells had more neurons four months after the transplantation than mice that had not been treated.

Although we were able to now detect more distinct T and B cell populations in the transplanted immunocompetent MRL and 129SvJ mice, the numbers of lymphoid cells remained far less than would be expected after bone marrow transplantation.