Not exact matches
In a series of experiments, the researchers found that 95 % of
mice vaccinated with the investigational cocktail were protected
against a lethal challenge with eight different
influenza strains expressing seven different
influenza A subtypes, compared to only 5 % of
mice who received mock vaccinations.
Data from in vivo
mouse models indicate that delivery of the DMAb sequence for the
influenza A-targeted monoclonal antibody protected
against lethal doses of two very different, clinically relevant
influenza A viruses.
Investigators showed the new strategy protected
mice — vaccinated
against the H3N2
influenza A flu strain, which causes mild disease — from succumbing to the more dangerous H5N1 and H7N9 strains weeks later.
«Engineers design programmable RNA vaccines: Tests in
mice show the vaccines work
against Ebola,
influenza, and common parasite.»
«Given these results in cells and
mice, it may be worthwhile to consider that patients receiving, or who may receive, Amphotericin B - based therapies be appropriately vaccinated
against influenza virus.
Several of the antibodies we isolated have broad neutralization capacity in vitro
against divergent
influenza strains and show potent prophylactic and therapeutic activity when used to treat
mice that were lethally infected with
influenza.
Protection of
mice against lethal challenge with 2009 H1N1
influenza A virus by 1918 - like and classical swine H1N1 based vaccines
Balazs AB, Bloom JD, Hong CM, Rao DS, Baltimore D. Broad protection
against influenza infection by vectored immunoprophylaxis in
mice.
Her research involves preclinical immunology and efficacy of vaccines
against H5N1 pandemic
influenza, malaria, and Mycobacterium tuberculosis using
mouse, ferret and guinea pig models.
Vaclac Vetvicka, Jana Vetvickova, «Glucan supplementation enhances the immune response
against an
influenza challenge in
mice,» Ann Transl Med, 2015 Feb; 3 (2): 22.