Sentences with phrase «mice fecal transplants»

Not exact matches

When the research team took fecal samples from responding patients and transplanted them into germ - free mice — «essentially reconstituting the mice's gut microbiomes with a responding patient's microbiome,» she says — they discovered that the mice had better immunity.

In additional tests, the scientists found they could restore the norovirus infections by transplanting fecal material from untreated mice into mice that earlier had been treated with the antibiotics.

Only six mice for each generation were examined, and only three animals received the final fecal transplant to restore their gut diversity.

By contrast, mice raised in the germ - free cages showed worse motor symptoms when they either were treated with microbial metabolites called short - chain fatty acids or received fecal transplants of gut microbes from patients with Parkinson's disease.

In the first study, scientists transplanted fecal material from exercised and sedentary mice into the colons of sedentary germ - free mice, which had been raised in a sterile facility and had no microbiota of their own.

Ridaura et al. (1241214; see the Perspective by Walker and Parkhill) obtained uncultured fecal microbiota from twin pairs discordant for body mass and transplanted them into adult germ - free mice.

When germ - free mice with no gut bacteria received fecal transplants from responders, they did better on PD - 1 blockers than did mice given nonresponder feces.

We transplanted fecal microbiota from adult female twin pairs discordant for obesity into germ - free mice fed low - fat mouse chow, as well as diets representing different levels of saturated fat and fruit and vegetable consumption typical of the U.S. diet.

The good bacteria seem to help the drugs by priming T cells, which Wargo's group reported were more abundant in the gut and tumors of the mice who got fecal transplants from responder patients.

Using fecal transplants, researchers transferred microbiota from IBS patients with or without anxiety into germ - free mice.

This will include a project funded by Stand Up to Cancer that involves fecal transplants from patients who responded to therapy and from non-responders into germ - free mice providing favorable and unfavorable microbiomes to study in detail.

To define a relationship between gut bacteria and the efficacy of ACT, the researchers transplanted fecal microbiota from Jackson mice to Harlan mice.

Today, in Microbiome Digest: interesting papers about Clostridium difficile, the use of Fecal Microbiota Transplant, studies in mice model, effect of Lactobacillus on Candida, antibiotic - resistant bacteria in sewerage biofilms, and more!

For example, 2013 saw studies showing that transplanting human fecal microbiota into mice could induce obesity and its associated metabolic phenotypes, and human data from a controlled study suggesting the procedure could treat recurrent C. difficileinfection.

Additionally, fecal transplant of gut microbes from obese mice to GF mice results in greater adiposity in the GF recipients than fecal transplants from lean donors (2).

In the first study, researchers transplanted fecal material from both exercised and sedentary mice into mice with sterile guts.