This was confirmed in a 2007 study by Rajkumar showing hormone treatment protected genetically engineered
mice from developing breast cancer.
In previous research, scientists have found that caffeine can protect lab
mice from developing an MS - like condition — by blocking part of the inflammatory process that damages nerves in the brain and spine.
Dr Ghigo said: «The inhibitor was able to completely protect
the mice from developing heart failure after doxorubicin treatment.»
Treatment also prevented around 20 percent of
mice from developing symptoms at all.
On the flip side, suppression of GPR158 protects
mice from developing depressive - like behaviors and make them resilient to stress.
Most importantly, these cells protected
mice from developing diabetes in a model of disease, having the critical ability to produce insulin in response to changes in glucose levels.
Injections of killed stem cells, designed to help the immune system recognise cancers, have been found to protect
mice from developing tumours
Not exact matches
When tissue
from the jaw region of a chick embryo is wrapped in tissue
from a
mouse embryo
from the region where teeth are formed and then incubated in the eye of an adult
mouse, the chick
develops teeth.
Researchers at the University of Michigan's Mary H Weiser Food Allergy Center have
developed a nasal vaccine that protects laboratory
mice from allergic reactions upon exposure to peanuts, after just three monthly doses.
Researchers at the University of Michigan's Mary H Weiser Food Allergy Center have
developed a nasal vaccine that protects laboratory
mice from allergic reactions upon exposure to peanuts, after just...
None of the adult
mice treated with antibiotics
developed colitis, but their pups exhibited a high risk for
developing colitis compared to those
from mothers that were not treated with antibiotics.
«We have
developed a drug candidate, a next - generation biologic medical product, and are now publishing the fantastic results
from the preclinical part where wound healing was strongly accelerated in
mice,» says Mia Phillipson, Professor at the Department of Medical Cell Biology, Division of Integrative Physiology, Uppsala University.
«Both the sleep and body temperature changes persisted in the smaller
mice after they were removed
from the physically and emotionally threatening environment, suggesting that they had
developed symptoms that look very much like those seen in people with long - term depression,» said Carlezon.
Researchers studied the effect in
mice of consuming feed enriched with oil
from glasshouse - grown genetically engineered Camelina sativa,
developed at the agricultural science centre Rothamsted Research.
«If the fluorescence molecules glow, this indicates that the
mouse is
developing chronic epileptic seizures,» says the molecular biologist Prof. Dr. Susanne Schoch
from the department of Neuropathology at the University of Bonn.
Mice transplanted with cells grown
from a patient suffering
from Huntington's disease (HD)
develop the clinical features and brain pathology of that patient, suggests a study published in the latest issue of Acta Neuropathologica by CHA University in Korea, in collaboration with researchers at Université Laval in Québec City, Canada.
A Japanese research team
from Kumamoto University has succeeded in
developing a refrigeration preservation technology that maintains the fertilization functionality of
mouse sperm for 10 days.
The team found that the levels of mitochondrial DNA, presumably released
from dying neurons, were increased in the blood plasma of
mice that were starting to
develop the symptoms of HD.
Researchers aware of this reality have now shown that transplanting gut bacteria
from wild
mice into «clean» lab
mice has made those rodents less likely to die
from the flu or
develop cancer.
When given to
mice rendered vulnerable to Zika, the antibody protected them
from developing serious infections.
Similarly, a 2013 study
from EPA scientists found that
mice exposed to ozone can
develop glucose intolerance, a precursor for diabetes.
When the researchers transferred gut microbes
from the twins into
mice predisposed to
develop a disease similar to MS, they found that after 12 weeks, three times as many
mice receiving bacteria
from MS patients
developed brain inflammation as those receiving microbes
from healthy donors.
Scientists
from the Memorial Sloan Kettering Cancer Center, US, have revealed a communication system between the knee joint and
developing bones in
mice, which controls bone growth during early development and after injury.
Dr. Katrin Busch
from Rodewald's team
developed genetically modified
mice by introducing a protein into their blood stem cells that sends out a yellow fluorescent signal.
Scientists
from the German Cancer Research Center (DKFZ) have
developed a way to equip
mouse blood stem cells with a fluorescent marker that can be switched on
from the outside.
Unlike rodent models, which are
developed from inbred strains of
mice kept in controlled environments, companion animals, like humans, are genetically diverse and are exposed to many of the same environmental influences as their owners are.
In a study in Nature Medicine, the team reported that vaccinated
mice and ferrets appeared to be protected
from dying of the H5N1 bird flu after receiving the vaccine, even when they
developed symptoms.
The scientists transferred the twins» gut bacteria to
mice predisposed to
develop a disease that mimics MS. Twelve weeks after the transplant, about 40 percent more
mice with gut microbes
from a twin with MS
developed brain inflammation compared with
mice that got gut microbes
from a twin without disease.
In the course of evolution, tetrapods
developed various body shapes and sizes —
from the
mouse to the dinosaur — to adapt to different environments.
During embryonic development of
mice, however, the situation is different: To build up the system, all mature blood and immune cells
develop much more rapidly and almost completely
from stem cells.
To test whether increased levels of Oprl1 could treat or prevent the
mice's PTSD symptoms, Ressler and his colleagues used a newly
developed compound
from the Scripps Research Institute that activates the receptor.
In this study, published in the October 31 issue of the Proceedings of the National Academy of Sciences, Sudhir Yadav PhD, a neuroimmunology post-doctoral fellow in the laboratories of Drs. Kouichi Ito, associate professor of neurology, and Suhayl Dhib - Jalbut, professor and chair of neurology, tested
mice that were engineered to have a pre-disposition for MS. Because
mice would not normally
develop MS, researchers used MS - associated risk genes
from real patients to genetically engineer
mice for this study.
Neunuebel
developed a sound system and analysis equations that allowed researchers to figure out — with up to 97 percent accuracy — which sound came
from which
mouse.
A new study has determined that
mice that spent time running on wheels not only
developed twice the normal number of new neurons, but also showed an increased ability to distinguish new objects
from familiar objects.
The researchers extracted mammary buds, the early
developing form of the mammary gland,
from 14 - day - old
mouse embryos, which is a critical time for mammary development in rodents, according to Speroni.
«When given to obese
mouse mothers during pregnancy and lactation, we found it protected their offspring
from developing symptoms of liver fat and damage that leads to NAFLD in early adulthood.»
But since that's not an option and
mice don't
develop symptomatic Charcot - Marie - Tooth (because
mice are small and their mitochondria don't have far to go), Dorn and his colleagues extracted sciatic nerves — the longest nerve in the body —
from mice and set up a way to compare the speeds of mitochondria moving up and down the nerves.
First author Professor Martin Hrabe de Angelis, Director of Institute of Experimental Genetics at the Helmholtz Zentrum München, who invented the
mouse clinic concept, said: «Our findings with regard to the genes examined are now available to the scientific community as a valid data set, which can be downloaded free of charge from the IMPC (International Mouse Phenotyping Consortium) website, and form an excellent basis on which we and other research groups can develop and test new hypotheses.&r
mouse clinic concept, said: «Our findings with regard to the genes examined are now available to the scientific community as a valid data set, which can be downloaded free of charge
from the IMPC (International
Mouse Phenotyping Consortium) website, and form an excellent basis on which we and other research groups can develop and test new hypotheses.&r
Mouse Phenotyping Consortium) website, and form an excellent basis on which we and other research groups can
develop and test new hypotheses.»
The paper doesn't include any genetic analysis of the final eggs that confirms they are healthy, notes Mitinori Saitou, a stem cell biologist at Kyoto University in Japan whose team
developed methods to create
mouse egg cells
from embryonic or reprogrammed stem cells.
Before birth,
mouse and human ovaries contain an abundant supply of germ cells, some of which will
develop into the eggs that will ultimately be released
from follicles during ovulation.
When a strain of
mice genetically destined to
develop a form of TLR7 - dependent lupus was crossbred with a strain in which TREML4 expression was suppressed, offspring lacking TREML4 were protected
from the development of lupus - associated kidney failure and had significantly lower blood levels of inflammatory factors and autoantibodies than did
mice expressing TREML4.
Mice that drank this water
from birth did not
develop gastric NETS, and in those where treatment was started later in the life cycle, the main causative biochemical alterations responsible for their development were blocked.
Not only did the normal
mice develop plaques, but also a pathology similar to «tangles» — twisted protein strands that form inside brain cells, disrupting their function and eventually killing them
from the inside - out.
When
mice bearing pancreatic tumors were injected with an antibody that prevents galectin - 9
from docking into dectin - 1, they
developed M1 macrophages, which sent signals that dramatically increased the number of T cells capable of attacking the cancer cells.
A study publishing October 1 in Cell Stem Cell reveals why these symptoms arise and tests an investigational drug in
mice that could prevent them
from developing.
He tried fertilizing a
mouse egg by injecting genetic material
from another female
mouse, but it didn't work: None of the
mice without any male genes
developed to term.
Researchers
from Southern Medical University in Guangdong, Guangzhou, China, have
developed an oral vaccine against Helicobacter pylori, the bacteria responsible for peptic ulcers and some forms of gastric cancer, and have successfully tested it in
mice.
When the scientists blocked Treg cells
from accumulating in the fat by targeting a molecule that the immune cells require,
mice no longer
developed type 4 diabetes in old age.
It is not known whether tryptophan byproducts
from L. reuteri induce the cells to
develop in people as they do in
mice, but defects in genes related to tryptophan have been found in people with inflammatory bowel disease.
Dr Jaan - Olle Andressoo
from the Institute of Biotechnology has
developed new transgenic
mice which have allowed researchers to gain much more reliable information on the physiological functions of GDNF.