Sentences with phrase «mice from developing»

This was confirmed in a 2007 study by Rajkumar showing hormone treatment protected genetically engineered mice from developing breast cancer.
In previous research, scientists have found that caffeine can protect lab mice from developing an MS - like condition — by blocking part of the inflammatory process that damages nerves in the brain and spine.
Dr Ghigo said: «The inhibitor was able to completely protect the mice from developing heart failure after doxorubicin treatment.»
Treatment also prevented around 20 percent of mice from developing symptoms at all.
On the flip side, suppression of GPR158 protects mice from developing depressive - like behaviors and make them resilient to stress.
Most importantly, these cells protected mice from developing diabetes in a model of disease, having the critical ability to produce insulin in response to changes in glucose levels.
Injections of killed stem cells, designed to help the immune system recognise cancers, have been found to protect mice from developing tumours

Not exact matches

When tissue from the jaw region of a chick embryo is wrapped in tissue from a mouse embryo from the region where teeth are formed and then incubated in the eye of an adult mouse, the chick develops teeth.
Researchers at the University of Michigan's Mary H Weiser Food Allergy Center have developed a nasal vaccine that protects laboratory mice from allergic reactions upon exposure to peanuts, after just three monthly doses.
Researchers at the University of Michigan's Mary H Weiser Food Allergy Center have developed a nasal vaccine that protects laboratory mice from allergic reactions upon exposure to peanuts, after just...
None of the adult mice treated with antibiotics developed colitis, but their pups exhibited a high risk for developing colitis compared to those from mothers that were not treated with antibiotics.
«We have developed a drug candidate, a next - generation biologic medical product, and are now publishing the fantastic results from the preclinical part where wound healing was strongly accelerated in mice,» says Mia Phillipson, Professor at the Department of Medical Cell Biology, Division of Integrative Physiology, Uppsala University.
«Both the sleep and body temperature changes persisted in the smaller mice after they were removed from the physically and emotionally threatening environment, suggesting that they had developed symptoms that look very much like those seen in people with long - term depression,» said Carlezon.
Researchers studied the effect in mice of consuming feed enriched with oil from glasshouse - grown genetically engineered Camelina sativa, developed at the agricultural science centre Rothamsted Research.
«If the fluorescence molecules glow, this indicates that the mouse is developing chronic epileptic seizures,» says the molecular biologist Prof. Dr. Susanne Schoch from the department of Neuropathology at the University of Bonn.
Mice transplanted with cells grown from a patient suffering from Huntington's disease (HD) develop the clinical features and brain pathology of that patient, suggests a study published in the latest issue of Acta Neuropathologica by CHA University in Korea, in collaboration with researchers at Université Laval in Québec City, Canada.
A Japanese research team from Kumamoto University has succeeded in developing a refrigeration preservation technology that maintains the fertilization functionality of mouse sperm for 10 days.
The team found that the levels of mitochondrial DNA, presumably released from dying neurons, were increased in the blood plasma of mice that were starting to develop the symptoms of HD.
Researchers aware of this reality have now shown that transplanting gut bacteria from wild mice into «clean» lab mice has made those rodents less likely to die from the flu or develop cancer.
When given to mice rendered vulnerable to Zika, the antibody protected them from developing serious infections.
Similarly, a 2013 study from EPA scientists found that mice exposed to ozone can develop glucose intolerance, a precursor for diabetes.
When the researchers transferred gut microbes from the twins into mice predisposed to develop a disease similar to MS, they found that after 12 weeks, three times as many mice receiving bacteria from MS patients developed brain inflammation as those receiving microbes from healthy donors.
Scientists from the Memorial Sloan Kettering Cancer Center, US, have revealed a communication system between the knee joint and developing bones in mice, which controls bone growth during early development and after injury.
Dr. Katrin Busch from Rodewald's team developed genetically modified mice by introducing a protein into their blood stem cells that sends out a yellow fluorescent signal.
Scientists from the German Cancer Research Center (DKFZ) have developed a way to equip mouse blood stem cells with a fluorescent marker that can be switched on from the outside.
Unlike rodent models, which are developed from inbred strains of mice kept in controlled environments, companion animals, like humans, are genetically diverse and are exposed to many of the same environmental influences as their owners are.
In a study in Nature Medicine, the team reported that vaccinated mice and ferrets appeared to be protected from dying of the H5N1 bird flu after receiving the vaccine, even when they developed symptoms.
The scientists transferred the twins» gut bacteria to mice predisposed to develop a disease that mimics MS. Twelve weeks after the transplant, about 40 percent more mice with gut microbes from a twin with MS developed brain inflammation compared with mice that got gut microbes from a twin without disease.
In the course of evolution, tetrapods developed various body shapes and sizes — from the mouse to the dinosaur — to adapt to different environments.
During embryonic development of mice, however, the situation is different: To build up the system, all mature blood and immune cells develop much more rapidly and almost completely from stem cells.
To test whether increased levels of Oprl1 could treat or prevent the mice's PTSD symptoms, Ressler and his colleagues used a newly developed compound from the Scripps Research Institute that activates the receptor.
In this study, published in the October 31 issue of the Proceedings of the National Academy of Sciences, Sudhir Yadav PhD, a neuroimmunology post-doctoral fellow in the laboratories of Drs. Kouichi Ito, associate professor of neurology, and Suhayl Dhib - Jalbut, professor and chair of neurology, tested mice that were engineered to have a pre-disposition for MS. Because mice would not normally develop MS, researchers used MS - associated risk genes from real patients to genetically engineer mice for this study.
Neunuebel developed a sound system and analysis equations that allowed researchers to figure out — with up to 97 percent accuracy — which sound came from which mouse.
A new study has determined that mice that spent time running on wheels not only developed twice the normal number of new neurons, but also showed an increased ability to distinguish new objects from familiar objects.
The researchers extracted mammary buds, the early developing form of the mammary gland, from 14 - day - old mouse embryos, which is a critical time for mammary development in rodents, according to Speroni.
«When given to obese mouse mothers during pregnancy and lactation, we found it protected their offspring from developing symptoms of liver fat and damage that leads to NAFLD in early adulthood.»
But since that's not an option and mice don't develop symptomatic Charcot - Marie - Tooth (because mice are small and their mitochondria don't have far to go), Dorn and his colleagues extracted sciatic nerves — the longest nerve in the body — from mice and set up a way to compare the speeds of mitochondria moving up and down the nerves.
First author Professor Martin Hrabe de Angelis, Director of Institute of Experimental Genetics at the Helmholtz Zentrum München, who invented the mouse clinic concept, said: «Our findings with regard to the genes examined are now available to the scientific community as a valid data set, which can be downloaded free of charge from the IMPC (International Mouse Phenotyping Consortium) website, and form an excellent basis on which we and other research groups can develop and test new hypotheses.&rmouse clinic concept, said: «Our findings with regard to the genes examined are now available to the scientific community as a valid data set, which can be downloaded free of charge from the IMPC (International Mouse Phenotyping Consortium) website, and form an excellent basis on which we and other research groups can develop and test new hypotheses.&rMouse Phenotyping Consortium) website, and form an excellent basis on which we and other research groups can develop and test new hypotheses.»
The paper doesn't include any genetic analysis of the final eggs that confirms they are healthy, notes Mitinori Saitou, a stem cell biologist at Kyoto University in Japan whose team developed methods to create mouse egg cells from embryonic or reprogrammed stem cells.
Before birth, mouse and human ovaries contain an abundant supply of germ cells, some of which will develop into the eggs that will ultimately be released from follicles during ovulation.
When a strain of mice genetically destined to develop a form of TLR7 - dependent lupus was crossbred with a strain in which TREML4 expression was suppressed, offspring lacking TREML4 were protected from the development of lupus - associated kidney failure and had significantly lower blood levels of inflammatory factors and autoantibodies than did mice expressing TREML4.
Mice that drank this water from birth did not develop gastric NETS, and in those where treatment was started later in the life cycle, the main causative biochemical alterations responsible for their development were blocked.
Not only did the normal mice develop plaques, but also a pathology similar to «tangles» — twisted protein strands that form inside brain cells, disrupting their function and eventually killing them from the inside - out.
When mice bearing pancreatic tumors were injected with an antibody that prevents galectin - 9 from docking into dectin - 1, they developed M1 macrophages, which sent signals that dramatically increased the number of T cells capable of attacking the cancer cells.
A study publishing October 1 in Cell Stem Cell reveals why these symptoms arise and tests an investigational drug in mice that could prevent them from developing.
He tried fertilizing a mouse egg by injecting genetic material from another female mouse, but it didn't work: None of the mice without any male genes developed to term.
Researchers from Southern Medical University in Guangdong, Guangzhou, China, have developed an oral vaccine against Helicobacter pylori, the bacteria responsible for peptic ulcers and some forms of gastric cancer, and have successfully tested it in mice.
When the scientists blocked Treg cells from accumulating in the fat by targeting a molecule that the immune cells require, mice no longer developed type 4 diabetes in old age.
It is not known whether tryptophan byproducts from L. reuteri induce the cells to develop in people as they do in mice, but defects in genes related to tryptophan have been found in people with inflammatory bowel disease.
Dr Jaan - Olle Andressoo from the Institute of Biotechnology has developed new transgenic mice which have allowed researchers to gain much more reliable information on the physiological functions of GDNF.
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