Sentences with phrase «mice in other studies»

The problems are many: Young blood didn't do much for old mice in other studies.

Not exact matches

While study results indicated that combining capsaicin with the chemicals «might promote cancer cell survival,» the report clearly stated that the control group of mice treated only with capsaicin ``... did not induce any skin tumors...» In addition, the study repeatedly cited other research studies in which the anti-cancer properties of capsaicin were solidly demonstrateIn addition, the study repeatedly cited other research studies in which the anti-cancer properties of capsaicin were solidly demonstratein which the anti-cancer properties of capsaicin were solidly demonstrated.

This study led to the discovery of 18 new imprinted genes, validated some known genes and resolved the disputed status of some others to provide a gold standard list of 93 imprinted genes in mouse.

As they studied brain activity in the knockout mice, the researchers also found prominent changes in a receptor in the brain known as mGluR5 and other proteins that support the function of neurons and synapses, said co-lead author Xiaoming Wang, M.D., Ph.D., senior research associate in Duke's department of pediatrics.

Jiang said autism researchers worldwide could use the mouse model to study ways to compensate for the gene and improve symptoms in people with autism spectrum disorders and Phelan - McDermid Syndrome, a more profound developmental condition caused by mutations to SHANK3 and other genes in chromosome 22.

For this study the researchers targeted very specific types of GABA receptors to improve social behaviors with clonazepam, but the team also found that by using a different drug, they could target other GABA receptors and actually reduce the ability to socially interact in normal mice — underscoring that future medications would need to target very specific receptors so as not to diminish the drug's impacts.

Inflammation in the gut helps bacterial viruses spread to other strains of bacteria and promotes their success, a new study in mice finds.

While the study used mice, COUP - TFII probably works the same way in other mammals, including humans, Donahoe says.

Three groups of middle - aged mice (about a year old) were studied: one group ate a normal diet, in which fewer than 30 percent of calories came from fat, while two others were fed high - calorie diets in which 60 percent of the calories came from fat.

In the Cell study, Dr. Massagué, with Fellow Manuel Valiente, PhD, and other team members, found that in mouse models of breast and lung cancer — two tumor types that often spread to the brain — many cancer cells that enter the brain are killed by astrocyteIn the Cell study, Dr. Massagué, with Fellow Manuel Valiente, PhD, and other team members, found that in mouse models of breast and lung cancer — two tumor types that often spread to the brain — many cancer cells that enter the brain are killed by astrocytein mouse models of breast and lung cancer — two tumor types that often spread to the brain — many cancer cells that enter the brain are killed by astrocytes.

In fact, both of the studies found that when adenosine was turned on in mouse tissue by other mechanisms, the pain response was equal to or better than the response generated by acupuncturIn fact, both of the studies found that when adenosine was turned on in mouse tissue by other mechanisms, the pain response was equal to or better than the response generated by acupuncturin mouse tissue by other mechanisms, the pain response was equal to or better than the response generated by acupuncture.

In the current study, Frank Longo, MD, PhD, and others at Stanford University, tested LM22A - 4, a drug that specifically binds to and activates the BDNF receptor TrkB on nerve cells, in mice that model the disordeIn the current study, Frank Longo, MD, PhD, and others at Stanford University, tested LM22A - 4, a drug that specifically binds to and activates the BDNF receptor TrkB on nerve cells, in mice that model the disordein mice that model the disorder.

The group's next steps will be to study whether the dynamic rearrangements of chromatin might be a much more general phenomenon in mouse tissues, controlling other physiological functions.

But now, two studies that map brain activity in living mice reveal that social experiences can influence brain responses to other mice.

«These are the same symptoms — alongside others — that we also found among mice in our earlier studies.»

«From other studies ***** we know that epigenetic modifications of the DPP4 gene, which are associated with an increased production of the enzyme, have a negative impact on the liver metabolism already in young mice, long before fatty liver disease emerges,» says Baumeier.

Two studies — one in mice and the other in human subjects — offer the first definitive evidence that exercise alone can change the composition of microbes in the gut.

In their study, the researchers showed that already at the age of six weeks in the mice with a rapid weight gain, the DPP4 gene was less methylated at four specific loci, i.e. epigenetically altered, compared to the other micIn their study, the researchers showed that already at the age of six weeks in the mice with a rapid weight gain, the DPP4 gene was less methylated at four specific loci, i.e. epigenetically altered, compared to the other micin the mice with a rapid weight gain, the DPP4 gene was less methylated at four specific loci, i.e. epigenetically altered, compared to the other mice.

«It also remains to be elucidated whether this phenomenon is particular for the mouse strain used in this study or is a more general phenomenon that also occurs in other genetic strains,» said Dr. Gerjo JVM van Osch, senior author of the Journal of Orthopedic Research article.

In a study published earlier this year, Jiang and other collaborators at Duke described a mouse model of autism in which they deleted a prominent autism gene called SHANK3, which is mutated in 1 percent of people with the disordeIn a study published earlier this year, Jiang and other collaborators at Duke described a mouse model of autism in which they deleted a prominent autism gene called SHANK3, which is mutated in 1 percent of people with the disordein which they deleted a prominent autism gene called SHANK3, which is mutated in 1 percent of people with the disordein 1 percent of people with the disorder.

And the trouble with extrapolating so much from mouse studies is that «nobody has actually shown over the long term how long these quote un-quote improvements persist, and we don't know whether it's broadly improving aspects of aging or it's specific to certain tissues,» said Matt Kaeberlein, a biologist who studies aging in dogs and other animal models at the University of Washington.

And while their study was performed in mice, the drug used has already been tested in clinical trials to treat other, unrelated conditions.

A compound derived from immune cells treats psoriasis in mice and holds promise for other autoimmune diseases, according to a new study from Washington University School of Medicine in St. Louis.

This new combination of electronics and drugs to intervene in an individual brain circuit might be used to create mouse models of other mood disorders for other studies, Dzirasa said.

In the current study, the researchers of Kanazawa University in collaboration with the researchers of Kagome Co., Ltd. compared the mice fed with high - fat food supplemented with sulforaphane and the others with high - fat food but without sulforaphane in terms of their body weighIn the current study, the researchers of Kanazawa University in collaboration with the researchers of Kagome Co., Ltd. compared the mice fed with high - fat food supplemented with sulforaphane and the others with high - fat food but without sulforaphane in terms of their body weighin collaboration with the researchers of Kagome Co., Ltd. compared the mice fed with high - fat food supplemented with sulforaphane and the others with high - fat food but without sulforaphane in terms of their body weighin terms of their body weight.

Now, a preclinical study, from the lab of Olivier Berton, PhD, an assistant professor in the department of Psychiatry, in collaboration with Sheryl Beck, PhD, a professor in the department of Anesthesiology at Children's Hospital of Philadelphia, found that bullying and other social stresses triggered symptoms of depression in mice by activating GABA neurons, in a never - before - seen direct relationship between social stimuli and this neural circuitry.

To investigate how this might contribute to disease, immunologists Nora Sarvetnick, Cecile King, and their colleagues at the Scripps Research Institute in La Jolla, California, studied mice predisposed to type 1 diabetes and other autoimmune disorders.

Philip Laipis of the University of Florida, who has also observed tumors in AAV vector - treated mice, agrees, at least for studies using a similarly high dose of AAV to target liver cells, which are more likely than other cell types to take up the AAV vector.

In another study of mice injected with GDF11, postdoc Lida Katsimpardi and others in the lab of Harvard neuroscientist Lee Rubin found that GDF11 also encourages growth of new blood vessels and olfactory neurons in the mouse braiIn another study of mice injected with GDF11, postdoc Lida Katsimpardi and others in the lab of Harvard neuroscientist Lee Rubin found that GDF11 also encourages growth of new blood vessels and olfactory neurons in the mouse braiin the lab of Harvard neuroscientist Lee Rubin found that GDF11 also encourages growth of new blood vessels and olfactory neurons in the mouse braiin the mouse brain.

Rodents gone mad In other schizophrenia news, a new transgenic mouse may allow researchers to better study the enigmatic disease, which afflicts one percent of people worldwide.

In the new study, Datta and his team discovered that necklace neurons in mice do not express GPCRs, unlike all other types of olfactory sensory neurons in mammalIn the new study, Datta and his team discovered that necklace neurons in mice do not express GPCRs, unlike all other types of olfactory sensory neurons in mammalin mice do not express GPCRs, unlike all other types of olfactory sensory neurons in mammalin mammals.

A preclinical study in mice published by Cell Press January 16th in the journal Cell reveals that drugs known as histone deacetylase inhibitors (HDACis) can enhance the brain's ability to permanently replace old traumatic memories with new memories, opening promising avenues for the treatment of posttraumatic stress disorder (PTSD) and other anxiety disorders.

Next, the team used other mouse models in which part of the lung was removed and single cell culture to study the plasticity of cell types during lung regrowth.

«This is the first study to offer an unbiased profile of novel imprinted genes in a mammal other than mice,» said lead author Xu Wang, a postdoctoral associate in the laboratory of Andrew Clark, professor of molecular biology and genetics and the study's senior author.

He also believes the technique will work reasonably well for studying the structure and function of proteins in most other model organisms, including laboratory mice.

A study reported in the Gut journal has shown that in mice, bacterial imbalance in the gut can lead to an inflammation similar to Crohn's disease, and this can be transmitted to other animals.

The researchers continue to study the effects of treatment in both mice and dogs, improve the photoswitch, and develop ways of attaching the photoswitch to other receptors, including some that could amplify the signal and allow perception of fainter light, as occurs normally in rods and cones.

The researchers, under the direction of Justin Rhodes of Beckman's NeuroTech Group and professor of psychology at Illinois, studied two groups of mice for two - and - a-half months: one group was fed a diet in which 18 percent of the calories came from fructose, mimicking the intake of adolescents in the United States, and the other was fed 18 percent from glucose.

«What we found early on was not all mice will mate with each other,» says clinical psychologist Melissa Farmer, who led the study while earning her Ph.D. at McGill University in Montreal, Canada.

Although we did observe positive effects on some aging traits, such as memory impairments and reduced red blood cell counts, our studies showed that similar drug effects are also seen in young mice, indicating that rapamycin did not influence these measures by slowing aging, but rather via other, aging - independent, mechanisms.»

The group plans to study Arp2 / 3's role in different parts of the brain and the role it has in the mouse's other symptoms, such as sociability defects and cognitive abnormalities.

After Mikovits and her research team's Science study appeared in October 2009, many other groups around the world reported that they could not find the mouse retrovirus, dubbed XMRV, in people who had CFS.

And, Wray says, given the growing ability of researchers to study enhancers and other DNA in mice, «my guess is there are probably other stories like this in the works.»

They and their collaborators began to study black and gray wolves living in Yellowstone National Park, first looking for differences in genes known to influence color in birds, mice, cattle, and other animals.

Russell Burke, a biologist at Hoftstra University in Hempstead, N.Y., who has studied Italian wall lizards in the U.S., says the species would be «at least as good as, and possibly better than» other bio-indicators, such as mice and plants.

Previous studies have found similar patterns in birds, mice and other animals, but this is the first time the phenomenon has been tested in humans, Samson said.

It's too soon to tell whether PZM21 and other molecules being studied in mice will ever end up as treatments for patients.

As in the first study, a group of young mice carrying the human gene APOE4 showed cognitive impairment on the behavioral level — in other words, they showed signs of damage on the level of spatial memory.

In the animal studies, mice containing the gene expressing human resistin and infected with a parasitic worm similar to the human hookworm experienced excessive inflammation, leading to increased weight loss and other symptoms.

This study, which will be published Oct. 24 in eLife, and two other new Northwestern studies in Oncotarget and Cell Cycle by the Peter group, describe the discovery of the assassin molecules present in multiple human genes and their powerful effect on cancer in mice.