Sentences with phrase «mice injected»

The consequence of this in REV - ERB KO mice injected with LPS was hyper - inflation.

In a study involving mice bred to be susceptible to tissue iron overload and hence to tuberculosis, treatment with lactoferrin significantly reduced the burden of tuberculosis organisms.7 And mice injected with Candida albicans, another iron - loving organism, had increased survival time when treated with lactoferrin.12 Lactoferrin is plentiful in raw milk.

Aids in weight loss Microbe - free mice injected with bacteria from obese people gained weight while mice injected with bacteria from thin people did not.

In fact, studies have shown that when fed the exact same diet, mice injected with gut microbes from malnourished children exhibited reduced growth when compared to mice that were given microbes from healthy children.

(F) Kaplan - Meier tumor - free survival curves comparing WAP - tva mice injected with RCAS - caErbB2 and then either kept as virgin or impregnated.

(E) Kaplan — Meier tumor - free survival curves comparing MMTV - tva and WAP - tva virgin mice injected with RCAS - caErbb2.

Parental HB1.F3 NSCs showed only background levels of green fluorescence and tumor sections from mice injected with these NSCs did not exhibit the green cobblestone pattern associated with membrane - bound antibody.

The research team confirmed those results by testing the four compounds at a low dose in mice injected with ovarian cancer cells.

Although this high dose elicited a seroconversion in all mice injected with either B31 - A3 (2/2) or ospC7 mutant bacteria (4/4), only mice inoculated with B31 - A3 became infected (2/2), as assessed by xenodiagnosis with larval ticks and reisolation from mouse tissues.

All three mice injected with WT bacteria seroconverted to B. burgdorferi antigens, and spirochetes were cultured from mouse tissues.

Memory improved in mice injected with a small, drug - like molecule discovered by UC San Francisco researchers studying how cells respond to biological stress.

These reagents, prepared against human light chain - related fibrils, recognize an epitope common to the beta - pleated structure of AL and other types of amyloid proteins and can effect rapid amyloidolysis when administered to mice injected with human AL amyloid extracts.

Mice injected with a strain of the Zika virus lived longer and were measured to have smaller tumors than the control group, which was injected with saltwater.

Moreover, three - dimensional (3D) μCT reconstruction of the tibia revealed that mice injected with control cells had a significantly higher degree of osteolysis with a decreased ratio of bone volume to total volume compared to mice injected with ABL1 / ABL2 knockdown breast cancer cells (Fig. 4, E and F).

For both experiments, tissues (ear skin, heart, bladder, spleen and tibiotarsal joints) of all mice injected with XT contents were uniformly culture - negative.

An study from has found that mice injected with induced pluripotent stem cells display immune system responses to a variety of cancers.

The XT from SCID mice injected with monkey XT contents were also uniformly negative by culture.

(a) Growth curves of primary tumors in non-obese diabetic / severe combined immunodeficiency disease (NOD / SCID) mice injected with 5 × 105 or 5 × 104 MDA - MB 231 and MDA - MB 231 F3 cells.

The cells of the mice injected with irisin needed more oxygen and burned more calories.

Peptide stimulation of T cells from Cbl - b − / − infected mice were similar in their ability to produce IFN - γ relative to WT controls (Fig. 5D), as previously seen in mice injected with a low dose of LCMV Docile (37).

Those mice injected with the astroglial cells displayed markers for Down syndrome, while those injected with the neurons did not.

No significant difference in body weight was observed in the groups treated with diabetic pancreas homogenate, containing IAPP aggregates or synthetic IAPP aggregates, prepared in vitro, compared with Tg - hIAPP mice injected with buffer (Fig. 8 A).

(A) The fasting blood glucose concentration was measured over time in Tg - hIAPP or WT mice injected with synthetic IAPP aggregates or PBS.

Fasting glycemia was measured periodically in Tg - hIAPP mice treated with synthetic IAPP aggregates or PBS as well as in WT mice injected with the same preparation of synthetic aggregates (Fig. 7 A).

The tumors grew rapidly in the control experiments (the median time for tumor - free survival was one week) and any differences in tumor - free survival for the controls and the mice injected with cells expressing mutated PREX2 were not statistically significant (Horrigan et al., 2017).

Kaplan - Meier analysis demonstrated that most of the mice injected with cells expressing wild - type PREX2 or GFP exhibited tumor - free survival for more than ten weeks.

Our findings are in agreement with a recently published study by Oskarsson et al. (2015) in which Tg mice injected through the tail vein with in vitro — generated aggregates from synthetic peptides containing the sequence of IAPP developed a higher percentage of IAPP aggregates in the pancreas than did untreated controls when subjected to a high - fat diet.

These abnormalities were not observed during the time of our experiments in Tg - hIAPP untreated mice or mice injected with pancreas homogenate without IAPP aggregates.

Here we report the discovery of an acute inflammatory condition that is mediated by Toll - like receptor (TLR) 2 and TLR6 and which induces hypoferremia in mice injected with TLR ligands.

Mice injected with the blocker - treated leukemia cells, however, only exhibited cancer in 2 % of their bone marrow cells.

When mice were immunized with the vaccine, they produced a 50-fold higher concentration of the potent IgG - type antibodies as compared to mice injected with the standard polysaccharide vaccine.

Human egg cells behaved the same way; when human ovary tissue was grafted into mice injected with PAH, the eggs died, the team reports in Nature Genetics online this month.

Twenty - four hours after the injection, the researchers saw large numbers of immune system white blood cells in tissue samples of the rodent brains near the site of injury of those mice injected with the cytokine IL - 1b, but not in the brain tissue of the control group of mice.

Mice injected with breast cancer cells making lots of a long strand of RNA called HOTAIR developed 10 times as many lung tumors as controls (left) did.

When born, mice injected with the miRNAs had the same abnormal behaviour as the stressed mice, whereas those injected with control RNA didn't, coming close to proving that the miRNAs transmitted the abnormal behaviour.

Mice injected with a virus genetically altered to help the rodents create an antibody designed to fight the malaria parasite produced high levels of the anti-malaria antibody.

Muscle fibres in old mice injected with GDF11 doubled in size to match that of 2 - month old mice.

Last week, after two batches of mice injected with the sample died, researchers cultured the sample and found growing, rod - shaped bacteria that looked like Bacillus anthracis.

Brain gains seen in elderly mice injected with human umbilical cord plasma.

Broady's team then studied the effects of NSI on mice injected with one of the six venoms.

Certainly, miRNA levels do not remain altered in the brain cells of mice injected with sperm miRNAs as zygotes.

In experiments involving mice injected with human GBM cells, the scientists also demonstrated that if either PTEN or DAXX were eliminated, then tumor growth occurred.

In a group of animals in which tiny implanted windows allowed direct imaging of brain tissue, the progression of A-beta plaque deposition was fastest in animals receiving APOE4 and slowest, sometimes even appearing to regress, in mice injected with APOE2.

Three mice injected with the new synthetic EPO showed bursts in the numbers of young red blood cells that rivaled levels in those injected with Procrit, a commercial EPO.

Tumor size in mice injected with the antibody steadily decreased over time, while their survival increased.

In another study of mice injected with GDF11, postdoc Lida Katsimpardi and others in the lab of Harvard neuroscientist Lee Rubin found that GDF11 also encourages growth of new blood vessels and olfactory neurons in the mouse brain.

Image shows the complex shape of individual oligodendrocytes (OLs) and myelin in adult mice injected with tamoxifen.

In studies of mice injected with human cancer cells, the drug appeared to work according to plan.

Unaltered cells created tumors in all seven mice injected with such cells, but when cells missing ALKBH5 were used, they caused tumors in only 43 percent (six out of 14) of mice.

When eight male and eight female researchers injected mice with ketamine, they saw the same results: mice injected by women did not respond to the drug.