Sentences with phrase «mice of these strains»

To try to exploit this phenomenon as a potential treatment, Datta injected large amounts of the peptides into young female mice of a strain prone to succumb to SLE.

Frozen material and live mice of strains that are maintained on shelf can be shipped within four weeks.

Mice of this strain show several behavioral differences from many other inbred strains.

Not exact matches

By tinkering with the position of the $ 219 keyboard, and accompanying devices like a joystick or mouse, users will strain their hands and wrists less.

The researchers found that these electric currents were much weaker in eyes from all three strains of diabetic mice than in healthy mice.

For their experiments, the researchers created hybrids of two genetically distinct mouse strains with a fully sequenced genome, allowing gene variants to be clearly assigned to the maternal or paternal allele.

Four strains of mice fared differently on four different diets, William Barrington of North Carolina State University in Raleigh reported July 15 at the Allied Genetics Conference.

This all remained a mystery until 1994, when Jeffrey Friedman and his colleagues at Rockefeller University reported their observations of two strains of mutant mouse, one called obese and the other called db.

Both strains of mice were extremely fat, a trait that was passed on to their offspring in a simple, dominant pattern of inheritance, like eye color.

Mice slathered with one strain of Staphylococcus epidermidis that makes the compound developed fewer...

Inflammation in the gut helps bacterial viruses spread to other strains of bacteria and promotes their success, a new study in mice finds.

In addition, the Merck institute — a nonprofit foundation set up by the giant drug company — is pulling together a committee of six prominent biologists who will select 150 clones for development into mouse strains over the next few years.

Lexicon's solution is to create a bank of genetically altered mouse cells that can quickly be used to develop knockout strains.

«He's used all of these [mouse] strains very elegantly to show that growth hormone really is a two - edged sword» (see Bartke Viewpoint).

Despite the presumed virulence of the strain — experiments with mouse lungs showed it produces 1000 times more bacteria in infected cells than do standard varieties — Valway says the number of TB cases that developed were kept in line with other typical outbreaks, which «shows that doing good contact investigations is important and preventative therapy works.»

This is a highly limiting factor for research, because it complicates the annotation of data obtained by molecular techniques, and because it has been shown that gut microbiomes are to some extent specific to their host, and researchers have been using strains of other origin in mouse models.

In a series of experiments, the researchers found that 95 % of mice vaccinated with the investigational cocktail were protected against a lethal challenge with eight different influenza strains expressing seven different influenza A subtypes, compared to only 5 % of mice who received mock vaccinations.

Although the mouse gut microbiome presents a number of similarities with the human microbiome, the work showed that around 20 percent of the strains in the collection prefer colonizing the intestines of mice.

Mice treated with a strain of S. epidermidis that does not make the compound 6 - HAP and then exposed to ultraviolet rays developed UV - induced tumors (left).

EATING RIGHT Different genetic strains of mice had varying reactions to eating a ketogenic diet (example of foods shown), a high - fat, low - carb diet.

Alf Hamann, from Deutsches Rheuma - Forschungszentrum and Charité Universitätsmedizin Berlin, Germany, and colleagues, did a comprehensive analysis of IL - 27 function in mice infected with a highly pathogenic influenza strain.

In their initial round of experiments, the group compared stretches of the mu opiate gene in eight different strains of mice.

Shapiro and his colleagues engineered a strain of E. coli used to treat gut infection to form gas compartments, and injected these bacteria into mice's bellies.

Brueckner's group looked for gene defects in two strains of mice with situs inversus, a mutation in which the heart, lungs, and other organs are inverted, like a mirror image.

In tests in mice, the researchers found that it could kill strains of Escherichia coli and Staphylococcus aureus that are resistant to most antibiotics.

In their next experiment, Arriaga placed a male strain of mouse that had what's considered a «tenor» voice inside a soundproof cage with a «baritone» so the two mice could only hear each other.

In the quest for an animal model of PD that mimics motor and non-motor symptoms of human PD, scientists have developed strains of mice that overexpress α - synuclein.

Up to this point, the best way to study epigenetic effects has been a strain of mice known as agouti viable yellow.

By studying a strain of mice bred to overexpress α - synuclein via the Thy - 1 promoter, scientists have found these mice develop many of the age - related progressive motor symptoms of PD and demonstrate changes in sleep and anxiety.

Redinbo and his team now characterize various forms of Beta - glucuronidase produced by different strains of bacteria residing in the gut, and they show that inhibiting GI bacterial Beta - glucuronidases in mice does not affect irinotecan that is circulating in the blood and is needed to combat cancer.

The vaccine protected mice against infection from strains of H1N1 that the mice had never been exposed to.

Then the researchers looked at the way those strains behaved in mice, ferrets and monkeys compared with two other types of H7N9: a less infectious version that first emerged in 2013 and the one isolated from the patient in 2016.

For one study in 2012 in Frontiers in Immunology, scientists from Canada injected these stem - recognizing antibodies into mice to see if the mice were shielded from a different strain of flu.

A new strain of mice with weak bones and stunted growth may become an important tool for researchers to study how bones gradually disintegrate in people who suffer from osteoporosis.

Unlike rodent models, which are developed from inbred strains of mice kept in controlled environments, companion animals, like humans, are genetically diverse and are exposed to many of the same environmental influences as their owners are.

Research with mice also suggested that genetic differences may cause one strain of mouse to gain weight on a diet that helps another strain slim down (SN: 8/20/16, p. 13).

A team led by Stanford developmental geneticist David Kingsley has been trying to unravel how a strain of mice called ank develop progressive ankylosis, or fusion of the bones, which completely immobilizes, and eventually kills, the animals by about 6 months of age.

The drug also eased respiratory symptoms and significantly improved survival of mice infected with a pandemic flu strain.

The team developed a strain of mice deficient in Bgn, the gene that makes biglycan.

The resulting mice lived for an average of around 840 days — more than 180 days longer than normally - conceived females from the same strain.

The most obvious genetic difference between long - lived and short - lived strains of mice is variation in the insulin / IGF gene.

«It also remains to be elucidated whether this phenomenon is particular for the mouse strain used in this study or is a more general phenomenon that also occurs in other genetic strains,» said Dr. Gerjo JVM van Osch, senior author of the Journal of Orthopedic Research article.

The difference might be subtle: Researchers have identified one strain of mice that seals up ear holes in weeks, whereas typical strains never do.

Medawar did not immediately appreciate the link to Owen's work, but when he saw the connection, he decided to inject fetal mice in utero with tissue from mice of a different strain.

They used a high dose of antibiotic to kill the native gut bacteria and then fed those mice fecal material from a protected strain.

Suspecting that metabolism (the speed at which calories are burned) might explain the discrepancy, the researchers compared the metabolic rates of two strains of mice: C57BL / 6 mice, which are known to enjoy the life - extending effects of dieting, and DBA / 2 mice, for whom dieting has been found to have no effect on life span.

In the new study, the Salk scientists used a mouse model of autism — an inbred strain of mouse previously found to display autism - like symptoms — to ask whether lowering the level of dicarbonyl methylglyoxal (a common byproduct of sugar metabolism) could alleviate symptoms of autism in the animals.

They tested the idea by switching out the gut bacteria in a susceptible strain of mice.

Put certain strains of mice on near - starvation but nutrient - rich diets, and they live 50 % longer than normal.

«Our study suggests that a lot of the genetic variation we see among these eight strains of mice is reflected in their microbiomes,» notes Rey, a UW - Madison professor of bacteriology and a corresponding author of the study.