Not exact matches
«Our research suggests that
in mice, males may be more vulnerable to the effects of maternal inflammation
than females, and the impact may be life long,» says study leader Irina Burd, M.D., Ph.D., an assistant professor of gynecology / obstetrics and neurology at the Johns Hopkins University School of Medicine and director of the Integrated Research Center for Fetal Medicine.
This permanent change gave the
mice a higher dose of MIS protein
than is found normally
in females.
Pregnant
female lab
mice received the brew
in their drinking water at four concentrations, from 400 parts per million (ppm) down to less
than 0.04 ppm — equivalent to one drop of pesticide
in 500 bathtubs of water, Porter says.
Likewise, male
mice with a Rett mutation have much more severe symptoms
than the
females do, says Zhong - wei Zhang, associate professor at the Jackson Laboratory
in Bar Harbor, Maine.
«It has become more and more obvious that
females in mice, birds, and all sorts of insects are mating with more
than one male,» Gowaty says, meaning that promiscuity cuts both ways.
To investigate, Akhtar deleted the gene for Rac1
in female mice; their first litter of pups survived, but they were smaller
than normal — probably because the milk they received contained less fat and protein
than normal.
Female mice spent five times as much time
in a place where they had encountered a dish with male urine
than at a place where they encountered water.
Female mice deprived of dietary zinc for a relatively short time before conception experienced fertility and pregnancy problems and had smaller, less - developed fetuses
than mice that ingested zinc during the same times, according to researchers
in Penn State's College of Agricultural Sciences.
Adult male
mice also started off with fewer of the lymphoid cells
in the lungs
than adult
females, the researchers found:
Female mice had about 1 1/2 times as many of these immune cells as males.
To explore that question, a team led by Cornell University biomedical engineer Claudia Fischbach first showed that
female mice that were obese, because of genetics or a high - fat diet, had more fibrous mammary fat pads with straighter collagen fibers
than those seen
in lean
mice (see image).
So when Drake and his colleagues measured the RNA levels — a direct link to how much of a gene is being produced —
in the genes of 334
mice, he didn't expect to find more
than a few variations that might help explain why males and
females have such different rates of cardiovascular disease and diabetes or why they react differently to certain drugs.
In addition, despite the genetic deletion, the
female deletion
mice have higher levels of ERK1
than the male deletion
mice.
The p - tau levels are higher
in female than in male
mice, and the increased p - tau was consistent with a proportional decrease
in the post-synaptic marker levels analyzed.
When the survival curve of males and
females were plotted independently, the reduction
in viability of p21 - null
mice was more pronounced for
females than for males (Fig. 1) ⇓.
When the researchers added cocaine to injured
mouse brains, they found that male
mice with concussions had more dopamine building up
in between cells
than did
females or non-injured
mice.
Bar Harbor, Maine — A research team led by Jackson Laboratory (JAX) Professor David Harrison, Ph.D., reports that acarbose, a drug that is frequently prescribed
in Europe for type 2 diabetes, extends the lifespan of
mice, with male
mice showing a more pronounced effect
than the
females.
In related research, also reported in Aging Cell, the researchers at the three institutions also showed recently that the lifespan - extending effects of rapamycin vary with both dosage of the drug and gender of the mice, with greater effect in females than male
In related research, also reported
in Aging Cell, the researchers at the three institutions also showed recently that the lifespan - extending effects of rapamycin vary with both dosage of the drug and gender of the mice, with greater effect in females than male
in Aging Cell, the researchers at the three institutions also showed recently that the lifespan - extending effects of rapamycin vary with both dosage of the drug and gender of the
mice, with greater effect
in females than male
in females than males.
7/5/2007 Why Liver Cancer Is More Prevalent
in Males
than in Females Production of a protein that promotes inflammation appears to be linked to the higher incidence of liver cancer
in men
than in women, researchers at the University of California, San Diego (UCSD) School of Medicine have determined
in mouse studies.
Although body weight was not different, liver weights were significantly higher (P < 0.01)
in 15 - mo - old
mice derived from IVC
in the presence of FCS
than in control animals (Supplemental Table S2); this phenotype was transmitted to F1 and F2 males derived from F0 IVC males but was not transmitted to F1
females.