Not exact matches
Dr. Tesar's team identified two promising drugs out of nearly 700
in the screen -
Miconazole, an ingredient
in over-the-counter treatments for fungal infections such as athlete's foot and clobetasol, a topical corticosteroid used for various skin conditions.
Not only were
Miconazole and clobetasol able to stimulate the differentiation of stem cells into mature oligodendrocytes, most importantly, these drugs stimulated the formation of new insulation (myelin) and reversed disease severity
in animal models of MS.. While not all adult tissues
in our body contain stem cells, this approach may change the way MS is managed.
In most cases the veterinarian will prescribe a topical ointment or cream that contains an anti-fungal such as Ketoconazole or
miconazole.
The most common topical solutions are
miconazole cream, Lotrimin cream, 1 % chlorhexidine ointment or dips
in lime sulfur or antiseptics.