A total of 24 mice were included in
the microarray expression study, four from each of the following groups: C57BL / 6J males, C57BL / 6J females, high fat — fed C57BL / 6J males, B6.Cg Ay / + females, B6.V Lepob / ob males, and B6.V Lepob / ob females.
Not exact matches
Whether you are
studying the
expression of thousands of genes simultaneously using DNA
microarrays, or the interaction of multiple molecules to understand intercellular signalling, the skills that will help you understand your findings are statistics, computational techniques, and modelling — so all you really need is a mathematician.
This
study, published in the journal
Microarrays, shows that lack of SOST in the bone microenvironment promotes the
expression of many genes associated with cell migration and / or invasion, including long non-coding RNA MALAT1 in prostate cancer, suggesting that SOST has an inhibitory effect on prostate cancer invasion.
Then they
studied the mice's lungs microscopically and, using
microarrays, measured the
expression of many dozens of genes in their lung tissue at 1, 3, and 5 days after infection.
The
expression rates of three macrophage - specific genes (Emr1, Cd68, and Csf1) that correlated with body mass in our
microarray studies, an adipocyte - specific gene (Acrp30), and proinflammatory genes (Tnfa, Nos2, Il6) were determined by quantitative RT - PCR.
In the present
study, we therefore used
microarray technology to investigate the concurrent
expression of 1,178 genes in the rat retina both following hypoxia and following a post-hypoxic 24 h reoxygenation period.
All
microarray data supporting the findings of this
study have been deposited in the National Center for Biotechnology Information Gene
Expression Omnibus (GEO) and are accessible through the GEO Series accession number GSE86885.
Interestingly, the
microarray experiments pursued in the present
study had identified low levels of Tie2
expression in all analysed pericyte populations.
Here we suggest a novel yet conceptually simple approach for deriving «Functional Association (s) by Response Overlap» (FARO) between
microarray gene
expression studies.
In the present
study we have reported the transcriptional profile of the two main components of the olfactory system in mice, obtained by RNAseq and
expression microarray.
The SMF's
microarray service offers a comprehensive set of integrated gene
expression services that facilitate
studying the role of genomic alterations and transcriptional regulation of genes.
Recently, a large - scale
microarray study characterized gene
expression differences between current, former, and never smokers [5], and identified specific genes related to xenobiotic functions, anti-oxidation, cell adhesion and electron transport to be more highly expressed in current smokers relative to never smokers.