Xu applied the DNA
microarray technique to screen more than 100,000 genes in the human genome to find the exact gene regulation pathway.
He worked there for 3 years, continuing his research on telomeres and pioneering
the microarray techniques that form the basis of his international reputation.
Hughes's winning research proposed using
microarray techniques to compare the genomes of a variety of vertebrate animals to test for common regulatory elements that determine gene expression.
It includes developmental genetics, dysmorphology, genetic counseling, prenatal diagnosis, molecular diagnostics,
microarray techniques in practice, community genetics and more..
Not exact matches
Whether you are studying the expression of thousands of genes simultaneously using DNA
microarrays, or the interaction of multiple molecules to understand intercellular signalling, the skills that will help you understand your findings are statistics, computational
techniques, and modelling — so all you really need is a mathematician.
As ICREA Prof. at ICFO Valerio Pruneri comments «the device means a major step forward for light microscopy
techniques, especially for
microarray platforms since it could definitely be used as a point - of - care tool in the diagnosis and treatment of major diseases such as Sepsis, a critical area where fast and accurate results can translate into life changing health outcomes for individuals.
In the relatively young field of
microarrays, technical positions are never mundane or boring, because there are always opportunities to evaluate and refine new
techniques and protocols as they become available.
Production Group: Focuses its efforts on producing
microarrays and refining manufacturing
techniques.
Bioinformaticians, robotics experts, and
microarray specialists all contribute to develop
techniques that support the institute's research endeavours.
One of the
techniques she uses is SNP
microarrays, which enable researchers to screen a genetic sample for many SNPs at once on specially designed DNA «chips».
Gene Set Enrichment Analysis (GSEA) is a
microarray data - mining
technique used to determine whether there is coordinated differential expression or «enrichment» in a set of functionally related genes when comparing control and experimental samples [35].
The facility collaborates with various research projects using flow cytometric
techniques to isolate and purify cells and chromosomes for structural and functional studies, sequencing,
microarrays as well as fluorescence insitu hybridisation (FISH) experiment.
Clinical Diagnostics The platform will provide service and support in order to promote and adapt the use of high throughput
techniques, such as next - generation sequencing,
microarray - based analyses and multiplex protein analysis, in routine diagnostics.
The high resolution that is achieved by these
techniques, particularly by
microarray technologies such as array comparative genomic hybridization, is blurring the traditional distinction between cytogenetics and molecular biology.
By directly comparing the gene expression estimates by these two
techniques, using a correlation with TaqMan qRT - PCR as a benchmark, we find RNAseq provides measurements over at least two orders of magnitude greater than the
microarray, and thus correlates better with TaqMan values across a large dynamic range.
While there are
techniques to identify known viruses, such as high throughput sequencing or high density
microarrays, identifying truly novel virions could pose a problem, the authors write.
Prior to working at City of Hope, she worked as a research associate in Dr. Peter Lee's lab at Stanford University since 2006 and facilitated in investigating mechanisms causing immune dysfunction in melanoma and breast cancer patients» peripheral blood, lymph node and tumor specimens utilizing
techniques including
microarray analysis, RT - PCR, Phospho - flow cytometry, histoloogy, and functional FACS studies.