Sentences with phrase «microarray technology»

In addition, surrounding laboratory spaces of Dr. Sykes» collaborators offer access to facilities and expertise in robotic nucleic acid extraction, real - time PCR, confocal microscopy, flow cytometry, microarray technology, and medical mycology.

«Low - Calorie Diet Slows Aging in Mice in Study,» claimed a recent headline.17 According to the article, «Putting elderly mice on a very low - calorie diet for as little as four weeks reversed many of the changes in the activity of various genes that had occurred during normal aging...» The resesearchers were not looking at actual signs of disease, nor were they measuring lifespan, but instead focused on the analysis of 11,000 different genes using a method called microarray technology in which Spindler has large financial holdings.

The challenge facing biologists now, say many Hutch scientists, is the need for new statistical models to extract useful information - a need that has not kept pace with the overwhelming number of experiments conducted using microarray technology.

Their newly developed statistical methods promise to enhance the power of microarray technology to identify sets of genes that cause disease, trigger developmental processes and allow individuals to respond to drugs.

In the present study, we therefore used microarray technology to investigate the concurrent expression of 1,178 genes in the rat retina both following hypoxia and following a post-hypoxic 24 h reoxygenation period.

The advent of microarray technology, with its capacity to monitor the expression of thousands of genes simultaneously, has provided a novel opportunity to identify individual genes, groups of genes, and related «gene families» associated with a given biologic process.

Traditionally, gene function was determined one gene at a time, but today's microarray technology enables scientists to monitor the expression of tens of thousands of genes on a single glass slide.

The University Health Network (UHN) Microarray Centre (MAC) is a leader in microarray technology.

The scientists then scanned the samples using microarray technology, which cuts genetic material into segments to provide a snapshot of which genes are active and which are asleep inside the cells.

Given that a few abundant transcripts dominate the milk fat layer transcriptome during mature lactation, we suspected that microarray technology, in which high abundance transcripts saturate the signal, would be particularly handicapped in this biological context.

Headquartered in San Diego, California, Illumina develops microarray technologies used in large - scale analysis of genetic variation and function.

As microarray technologies continue to develop, the chemistry underlying the biology will increasingly come to the forefront.

The high resolution that is achieved by these techniques, particularly by microarray technologies such as array comparative genomic hybridization, is blurring the traditional distinction between cytogenetics and molecular biology.

It focusses on next - generation sequencing and microarray technologies, although it is likely to go off on tangents from time - to - time.

Not exact matches

Natera uses a SNP microarray from Ilumina with a proprietary technology called Parental Support ™, which tests all 24 chromosomes and delivers results that are typically > 99 % accurate.

In the microarray experiment, the range in relative abundances of the 500 most highly expressed genes is very narrow (Figure 1 inset), especially in contrast to RNA - Seq technology (Figure 1).

Larger biomarker signatures can be detected with technology from CDI Laboratories, which offers microarrays of functional human proteins (over 20,000 on a single array) to test the antibodies present in human liquid biopsy samples, such as blood, serum, plasma, CSF, or tissue lysates.

The technology for genome - wide profiling using microarrays was newly available, and with it came tremendous excitement, parallel to the mapping of the human genome.

My role there involved technology development for microarray - based genetic analysis.

Microarrays are a perfect example of a convergence technology where multidisciplinary fields are required to make the technology a reality and to cause it to evolve.

«The genetic content that goes on a microarray is as important as the technology itself,» he says.

To do so, they used so - called microarrays, a chip technology originally developed for the semiconductor industry.

Some research teams over the past five years have used microarray or gene - chip technology to compare genomes and quickly scan them for variations of copy numbers on each chromosome.

First author Dr Reza Haqshenas said the researchers then used gene silencing technology to determine whether the genes» cell factors identified using the antibody microarray were indeed important for HCV replication and therefore potential targets for anti-HCV compounds.

Laurence Rubin, Identitas CEO and a practicing rheumatologist at St. Michael's Hospital in Toronto, says that his company is now shifting gears from demonstrating the utility of SNP - based microarrays for analyzing forensic samples to into more of an advocacy role, introducing law enforcement agencies to the power of these genomic technologies.

Results: Benefiting from the recently sequenced genome of the model sulfate - reducing bacterium (SRB), Desulfovibrio vulgaris, microbiologist Weiwen Zhang and a team of scientists at Pacific Northwest National Laboratory (PNNL) are applying a suite of post-genomics technologies, including microarray, proteomic, and computational analyses, to obtain a broader understanding of D. vulgaris» metabolism.

The completion of a draft genome sequence for the microorganism Methanosarcina barkeri has enabled use of high - throughput technologies such as microarrays and mass spectrometry of proteins to detect global changes that occur in response to experimental treatments.

Another widely used technology to profile gene expression levels is microarrays.

The students are employing that technology — which includes CRISPR (clustered regularly interspaced short palindromic repeats) systems, DNA microarrays, real - time polymerase chain reactions, RNA sequencing and western blotting — to study acute myeloid leukemia (AML), which affects both children and adults and comes with a high mortality rate for older patients.

The core has been well equipped with updated, emerging and cutting - edge technologies and platforms, such as next generation sequencing and microarray, to explore genetic changes of both RNA and DNA levels.

He is using a new microarray analysis technology that assesses more then 23,000 genes.