Sentences with phrase «microarrays at»

To gain a deeper understanding of the cellular response of the two neurotoxins, the researchers applied global quantitative proteomics at the U.S. Department of Energy's national user facility — the Environmental Molecular Sciences Laboratory — and microarrays at UCLA to assay the protein and gene levels, respectively, for both neurotoxins.

Other proteins can't be put on a microarray at all because they are part of a cell membrane and need to be attached to their membranes to function.

Not exact matches

There are and will continue to be jobs at companies that develop instruments and kits, such as microarrays, reagents, expression kits, and other supplies to fuel research programs.

As ICREA Prof. at ICFO Valerio Pruneri comments «the device means a major step forward for light microscopy techniques, especially for microarray platforms since it could definitely be used as a point - of - care tool in the diagnosis and treatment of major diseases such as Sepsis, a critical area where fast and accurate results can translate into life changing health outcomes for individuals.

Gene microarrays, which measure expression of dozens of genes at once, can be fickle and supply inconsistent results.

Working at a microarray core facility is not where many of us thought we would be today, simply because microarrays were not as popular (or even around!)

Traditionally, gene function was determined one gene at a time, but today's microarray technology enables scientists to monitor the expression of tens of thousands of genes on a single glass slide.

Then they studied the mice's lungs microscopically and, using microarrays, measured the expression of many dozens of genes in their lung tissue at 1, 3, and 5 days after infection.

Once that is done, Cary and his colleague Alison Murray at the Desert Research Institute in Reno, Nevada, plan to test samples against microarrays to determine a «core metabolism» shared by all members of the community.

Microarrays allow researchers to acquire data about expression levels of thousands of genes at one fell swoop.

One of the techniques she uses is SNP microarrays, which enable researchers to screen a genetic sample for many SNPs at once on specially designed DNA «chips».

DNA microarrays, also called DNA chips, have stoked excitement in the research community because they can test the activity of many genes at once.

Using microarrays that enabled them to examine 100,000 sites on the genome, they looked at the cells» nuclear DNA, mitochondrial DNA, and methylation patterns (which give clues to whether a gene has been turned on or off).

We used the Virochip, a microarray designed to detect all viruses, to identify a new species of adenovirus (TMAdV, or titi monkey adenovirus) that caused a deadly outbreak in a colony of New World titi monkeys at the California National Primate Research Center (CNPRC), and also infected a human researcher.

Samples of cRNA derived from single animals were hybridized in recommended buffer to microarrays (Murine Genome Array U74Av2, Affymetrix Inc.) at 45 °C for 16 hours.

Here we applied the Virochip, a pan-viral microarray, to identify a novel adenovirus (TMAdV, titi monkey adenovirus) as the cause of a deadly outbreak in a closed colony of New World monkeys (titi monkeys; Callicebus cupreus) at the California National Primate Research Center (CNPRC).

Antibody microarrays are powerful tools for simultaneous detection of hundreds or thousands of blood - borne protein biomarkers at once, potentially allowing accurate fingerprinting and improved diagnostics of complex pathophysiological states such as cancers, neurodegenerative diseases and autoimmune conditions.

Microarray analysis was performed at different time points to determine yeast genome - wide response when exposed to salt, acid, hypoxic conditions, and hydrogen peroxide, as well as ethanol, isopentenol, and other biofuels candidates.

Laurence Rubin, Identitas CEO and a practicing rheumatologist at St. Michael's Hospital in Toronto, says that his company is now shifting gears from demonstrating the utility of SNP - based microarrays for analyzing forensic samples to into more of an advocacy role, introducing law enforcement agencies to the power of these genomic technologies.

Calcification rate measurements and gene expression analysis by microarray RNA transcriptional profiling at two time - points (midday and night - time) revealed several genes common within mammalian gene regulatory networks.

The names of samples within the microarray analysis were labeled C11 and T11 as for control (reference) and treatment at daytime (11:00), respectively.

Results: Benefiting from the recently sequenced genome of the model sulfate - reducing bacterium (SRB), Desulfovibrio vulgaris, microbiologist Weiwen Zhang and a team of scientists at Pacific Northwest National Laboratory (PNNL) are applying a suite of post-genomics technologies, including microarray, proteomic, and computational analyses, to obtain a broader understanding of D. vulgaris» metabolism.

At Berkeley, she developed computationally intensive statistical methods for the analysis of microarray data with applications in cancer biology.

«I think these diagnostic polymer foils are very interesting alternatives to standard DNA microarrays, especially when it comes to point of care diagnostics», says Associate Professor Aman Russom, group leader of the Clinical Microfluidics group in the Nanobiotechnology laboratory at KTH.

The aim of his research was to use microarray gene expression data in order to characterize ageing in different human tissues and identify the age at which major changes in genetic expression profiles occur.

By directly comparing the gene expression estimates by these two techniques, using a correlation with TaqMan qRT - PCR as a benchmark, we find RNAseq provides measurements over at least two orders of magnitude greater than the microarray, and thus correlates better with TaqMan values across a large dynamic range.

By enabling compound binding profiles to be rapidly generated, the HuProt microarray has become an indispensible tool at the forefront of drug discovery and development..

Waters, who is director of biological sciences at PNNL, was invited to be on the committee because of her strong expertise in microarray and omics data analysis.

With the development of DNA microarrays, the gene chips that allow scientists to read the output of thousands of genes at once, along with robotics and computers, scientists tear through hefty analyses with previously unheard - of swiftness.

The mission of the Sequencing and Microarray Facility is to support genomics research at MDACC by providing investigators with access to state - of - the - art instrumentation and a high level of technical expertise in a centralized facility, thereby minimizing the duplication of expensive equipment, maintaining technical excellence and enhancing research collaborations.

Samples were labeled with Cy3 fluorescent dye, normalized to 10 pmol of incorporated dye, and hybridized overnight to the ViroChip microarray for 16 hr at 65 °C.

Microarray data from an experiment looking at oral - cancer development prompts a conversation in the Public Health Sciences lab of Dr. Chu Chen by (from left) Drs. Lue Ping Zhao, PHS investigator; Chun Cheng, PHS postdoctoral fellow; Chen and Eduardo Mendez of the University of Washington Department of Otolaryngology - Head and Neck Surgery.

Prior to working at City of Hope, she worked as a research associate in Dr. Peter Lee's lab at Stanford University since 2006 and facilitated in investigating mechanisms causing immune dysfunction in melanoma and breast cancer patients» peripheral blood, lymph node and tumor specimens utilizing techniques including microarray analysis, RT - PCR, Phospho - flow cytometry, histoloogy, and functional FACS studies.

«Low - Calorie Diet Slows Aging in Mice in Study,» claimed a recent headline.17 According to the article, «Putting elderly mice on a very low - calorie diet for as little as four weeks reversed many of the changes in the activity of various genes that had occurred during normal aging...» The resesearchers were not looking at actual signs of disease, nor were they measuring lifespan, but instead focused on the analysis of 11,000 different genes using a method called microarray technology in which Spindler has large financial holdings.

«When you actually look at some of the diets experimentally, doing what we call heat maps (DNA or RNA microarray), you will see the enzymes that are turned on, upregulated, and pro-inflammatory initially in a patient with a particular disease.

The microarray data are available at http://www.ncbi.nlm.nih.gov/geo under the accession number GSE50674.

Differentially methylated regions from the microarray analysis with varying p values (between 0.0001 and 0.03 with FDR < 0.2) and fold differences (Log2 CPA / Controls between 1.1 and 0.5) at the probe level were selected for validation.

B. Heatmap depicts normalized intensities of microarray probes contained in promoters (at most one per promoter) that best differentiate between CPA and control groups.