Sentences with phrase «microbial genomes»

This mechanism is already known to play a huge role in the evolution of microbial genomes, but its consequences have hardly been explored.

They compared the complete sequence to those in a database containing all 20 known complete microbial genome sequences on file.

Using microbial genomes as a data source meant researchers could link newly identified virus sequences to the proper microbial host.

The objectives of this initial work are to sequence the genomes of 200 microbes that have been isolated from the human body as part of the 1,000 microbial genomes collection.

An ensemble strategy that significantly improves de novo assembly of microbial genomes from metagenomic next - generation sequencing data.

Similarly, the standardized microbial genomes in NIST RM 8375 can be used to assess the performance of high - throughput methods for microbial DNA sequencing.

Even without an immediate pay - off, TIGR says the project provided experience in comparing microbial genomes that could be useful in future outbreaks.

The genome contains 3 to 4 times more DNA than other microbial genomes sequenced so far, and it's chock full of useful genes with relatively little useless DNA in the way.

Having obtained my PhD degree in Microbiology at Wageningen University (The Netherlands) I moved to Sweden with my family to work at Uppsala University to focus on microbial genome evolution.

That's unusual; most microbial genomes consist of a single chromosome, sometimes with some extra genes carried on bits of extraneous DNA called plasmids.

XtalPred provides: (1) a detailed comparison of the protein's features to the corresponding distribution from TargetDB; (2) a summary of protein features and predictions that indicate problems that are likely to be encountered during protein crystallization; (3) prediction of ligands; and (4)(optional) lists of close homologs from complete microbial genomes that are more likely to crystallize.

The Streptococcus pneumoniae Genome Diversity Project More information about S. pneumoniae, on a site supported by vaccine manufacturer Wyeth - Lederle List of the more than 45 microbial genomes so far completed, with links to others still in progress

The meeting will focus on DNA transfer and genome repair and consequences for microbial genome instability, fitness for survival and virulence.

So Comas is trying to shed light on «the general rules of microbial genome evolution applying bioinformatics approaches,» and «to develop tools for the evolutionary genomic analysis of bacteria,» he says.

Now, an extensive analysis of microbial genomes suggests that more than half of bacteria home in on chemical cues to reach a target, an ability called chemotaxis.

Another four strains are being sequenced by publicly funded laboratories and at least two by companies, making this the most sequenced microbial genome yet.

At roughly 48,000 years old, it's the oldest microbial genome sequenced, the researchers report.

The studies open up new opportunities to uncover microbial genomes from other environments, revealing how microbes alter global carbon and nitrogen cycles, how microbial metabolism evolved, and how so many different kinds of microbes can coexist, says biological oceanographer Paul Falkowski of Rutgers University in New Brunswick, New Jersey.

A team of scientists announced that they have sequenced the genome of the common soil bacterium Streptomyces coelicolor — the largest microbial genome to date — unearthing both promising and surprising genomic features.

«This study establishes that a body's collection of microbial genomes provides a store of information about its history,» said Knight, also an associate professor of chemistry and biochemistry and a Howard Hughes Medical Institute Early Career Scientist.

«Mining sequence data in DOE JGI's Integrated Microbial Genomes & Microbiomes system, which houses thousands of metagenomes, allowed us to find evolutionary relatives of our Klosneuvirus,» Schulz said.

Ecological selection for small microbial genomes along a temperate - to - thermal soil gradient — Jackson W Sorensen — bioRxiv

A Sanger / pyrosequencing hybrid approach for the generation of high - quality draft assemblies of marine microbial genomes.

Learning more about this so - called «microbial dark matter» involves extracting microbial genomes from the amplified DNA of single cells and from metagenomes.

By this summer, the consortium plans to set up a new Ruminant Microbial Genome Database on TIGR's website.

The sequencing of M. jannaschii was funded by the US Department of Energy (DOE)'s Microbial Genome Project, which, since 1994, has investigated microbes that might be useful in environmental cleanup, energy production, or other aspects of DOE's mission.

Genetic engineering usually involves the transfer of individual genes from one microbe or cell to another; synthetic biology envisions the assembly of novel microbial genomes from a set of standardized genetic parts that are then inserted into a microbe or cell.

The availability of a large number of complete microbial genomes and the technology of high - volume DNA sequencing has enabled the genotyping of gut microbiomes under different dietary and health conditions, leading to new, detailed understanding of the differences between healthy and unhealthy gut microflora.

Putman then extended Wikidata with a focus on microbial genomes.

In this study, we evaluated the utility and cost - effectiveness of a hybrid sequencing approach using 3730xl Sanger data and 454 data to generate higher - quality lower - cost assemblies of microbial genomes compared to current Sanger sequencing strategies alone.

Using metabolic function analyses of identified genes, we compared our human genome with the average content of previously sequenced microbial genomes.

In a global culture increasingly driven by scientific and technological innovation, research in areas ranging from microbial genomes to the human brain will become ever more inextricably linked to public health, medicine, and industry.

The sorter scoured public databases of sequenced microbial genomes, looking for fragments of genomes that resembled virus genomes that had already been sequenced — for starters.

They found that the microbial genomes from some patients differed widely from one another, just as you'd expect with environmental infections.

«In addition, we will likely identify novel genes and functional elements in microbial genomes that will reshape the way we think about and approach human biology.»

Venter, who pioneered the sequencing of microbial genomes, estimated that 50 to 100 more genomes needed to be sequenced to help triangulate back to the last common ancestor.

The team, including collaborators at the University of Utah led by John Parkinson, compared thousands of chemoreceptor sequences from all microbial genomes in the Microbial Signal Transduction database available as of August 2012.

Conclusions We described NaS tool, a hybrid approach allowing the sequencing of microbial genomes using the MinION ® device.

Pseudomonas Genome Database: facilitating user - friendly, comprehensive comparisons of microbial genomes.

Lecture 4: Replication - strand specific oligomer bias in bacterial genomes Coffee break Methods to Compare Microbial Genomes Lecture 5: 20 Methods to Compare Microbial Genomes

«We knew we could boot up a virus from our synthetic DNA, but nobody had ever transplanted a microbial genome, specifically one made from scratch with four bottles of chemicals,» Venter told The Washington Post.

They helped reveal the transcription start sites and antisense transcripts of microbial species, improving the microbial genome annotation.

Microbial genome sequencing promises much, but many barriers exist to its routine deployment.

While not suitable for whole - genome or even whole - exome sequencing, these platforms have dozens of other applications: microbial genomes, BACs or cDNAs, targeted (PCR) validation of mutations or structural validation.

«Even though a microbial genome is one - thousandth the size of the human genome, the total number of microbial genes in [the human] body is much greater than human genes because you have so many different species,» says Weinstock.