Sentences with phrase «microbial genomes in»

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They identified microbial genes and their activity with help from DOE's Joint Genome Institute in Walnut Creek CA.

The result was an extremely high - throughput sequencing protocol that, in a single run, can cover portions of the genomes of over 50,000 microbial cells (2).

In a global culture increasingly driven by scientific and technological innovation, research in areas ranging from microbial genomes to the human brain will become ever more inextricably linked to public health, medicine, and industrIn a global culture increasingly driven by scientific and technological innovation, research in areas ranging from microbial genomes to the human brain will become ever more inextricably linked to public health, medicine, and industrin areas ranging from microbial genomes to the human brain will become ever more inextricably linked to public health, medicine, and industry.

«Knowing which microbes live in various ecological niches in healthy people allows us to better investigate what goes awry in diseases thought to have a microbial link, like Crohn's disease and obesity,» says George Weinstock, associate director of the Genome Institute at Washington University in St Louis and one of the Human Microbiome Project's principal investigators.

In a perspective piece published November 6 in the journal Science, Eddy Rubin, Director of the U.S. Department of Energy Joint Genome Institute (DOE JGI), a DOE Office of Science User Facility, along with Microbial Program Head Tanja Woyke, discusses why the time is right to apply genomic technologies to discover new life on EartIn a perspective piece published November 6 in the journal Science, Eddy Rubin, Director of the U.S. Department of Energy Joint Genome Institute (DOE JGI), a DOE Office of Science User Facility, along with Microbial Program Head Tanja Woyke, discusses why the time is right to apply genomic technologies to discover new life on Eartin the journal Science, Eddy Rubin, Director of the U.S. Department of Energy Joint Genome Institute (DOE JGI), a DOE Office of Science User Facility, along with Microbial Program Head Tanja Woyke, discusses why the time is right to apply genomic technologies to discover new life on Earth.

But the genome sequences revealed in this study suggest that there are many more prophage - like viruses that are different in one important respect: Their genome remains separate from their microbial hosts» genome.

Now, an extensive analysis of microbial genomes suggests that more than half of bacteria home in on chemical cues to reach a target, an ability called chemotaxis.

Even without an immediate pay - off, TIGR says the project provided experience in comparing microbial genomes that could be useful in future outbreaks.

Their microbial exposures varied and gene expression patterns varied, but the parts of the genome that were open at each location in the gut remained consistent, Crawford said.

The studies open up new opportunities to uncover microbial genomes from other environments, revealing how microbes alter global carbon and nitrogen cycles, how microbial metabolism evolved, and how so many different kinds of microbes can coexist, says biological oceanographer Paul Falkowski of Rutgers University in New Brunswick, New Jersey.

The Streptococcus pneumoniae Genome Diversity Project More information about S. pneumoniae, on a site supported by vaccine manufacturer Wyeth - Lederle List of the more than 45 microbial genomes so far completed, with links to others still in progress

The genome contains 3 to 4 times more DNA than other microbial genomes sequenced so far, and it's chock full of useful genes with relatively little useless DNA in the way.

A team led by Jose García - Bustos of GlaxoSmithKline's molecular microbiology division in Tres Cantos, Spain, published the annotated but incomplete genome of a virulent, antibiotic - resistant S. pneumoniae strain in the June issue of Microbial Drug Resistance.

«Mining sequence data in DOE JGI's Integrated Microbial Genomes & Microbiomes system, which houses thousands of metagenomes, allowed us to find evolutionary relatives of our Klosneuvirus,» Schulz said.

For example, the large - scale sequencing program has already started to sequence the genomes of 100 microorganisms found in the human gut, and will build on this by using genomic sequencing to characterize the complex microbial communities found at many sites in and on the human body.

For instance, the Human Microbiome Project (HMP)(Turnbaugh et al, 2007; Peterson et al, 2009; Huttenhower et al, 2012) and MetaHIT (Qin et al, 2010) have generated maps of bacterial species abundances throughout the human body, reference genomes, and catalogs of more than 100 million microbial genes assembled from shotgun sequencing of in vivo communities.

A holistic understanding of the role of Earth's microbial community and its genome — its microbiome — in the biosphere and in human health is key to meeting many of the challenges that face humanity in the twenty - first century, from energy to infection to agriculture.

In a milestone for the medical and scientific community, he re-engineered the microbial CRISPR - Cas9 system for genome editing in human cellIn a milestone for the medical and scientific community, he re-engineered the microbial CRISPR - Cas9 system for genome editing in human cellin human cells.

«Our goal is to discover what microbial communities exist in different parts of the human body and to explore how these communities change in the presence of health or disease,» said National Human Genome Research Institute Director, Francis S. Collins, M.D., Ph.D., co-chair of the Human Microbiome Project Implementation Group.

Symbiosis in the microbial world: from ecology to genome evolution — Jean - Baptiste Raina — Biology Open

Metagenomic Exploration of Microbial Signatures on Periyar River Sediments from the Periyar Tiger Reserve in the Western Ghats — Aparna Chakkamadathil Rajeev — Genome Announcements

The genome, transcriptome, proteome, and metabolome are four of the tools in our toolbox that we can actually use to examine the microbial world.

The results suggest that the sequenced genomes define two microbial groups: one composed of only a few taxa that are nearly always abundant in picoplanktonic communities, and the other consisting of many microbial taxa that are rarely abundant.

Our method, based ideally on 20x and 50x of NaS and Illumina reads respectively, provides an efficient and cost - effective way of sequencing microbial or small eukaryotic genomes in a very short time even in small facilities.

Lecture 4: Replication - strand specific oligomer bias in bacterial genomes Coffee break Methods to Compare Microbial Genomes Lecture 5: 20 Methods to Compare Microbial genomes Coffee break Methods to Compare Microbial Genomes Lecture 5: 20 Methods to Compare Microbial Genomes Lecture 5: 20 Methods to Compare Microbial GenomesGenomes

The research team took an unbiased whole genome approach and found significant differences in several unrelated processes, especially among genes involved in producing antibodies to potential microbial invaders.

In their role as dinner, bacteria also likely provided raw genetic material for the first animals, which probably incorporated chunks of microbial DNA directly into their own genomes as they digested their meals.

A few interesting articles in early life human microbiome, plus: A comparison between Staphylococcus epidermidis commensal and pathogenic lineages from the skin of healthy individuals living in North American and India; A new tool to reconstruct microbial genome - scale metabolic models (GSMMs) from their genome sequence; The seasonal changes in Amazon rainforest soil microbiome are associated with changes in the canopy; A specific class of chemicals secreted by birds modulates their feather microbiome; chronic stress alters gut microbiota and triggers a specific immune response in a mouse model of colitis; and evidence that the short chain fatty acids profile in the gut reflects the impact of dietary fibre on the microbiome using the PolyFermS continuous intestinal fermentation model.

Now, scientists are a step closer to understanding how antibiotic resistance spreads in the microbial world because the genomes of two gut bacteria have been sequenced.

Having obtained my PhD degree in Microbiology at Wageningen University (The Netherlands) I moved to Sweden with my family to work at Uppsala University to focus on microbial genome evolution.

The sequencing of M. jannaschii was funded by the US Department of Energy (DOE)'s Microbial Genome Project, which, since 1994, has investigated microbes that might be useful in environmental cleanup, energy production, or other aspects of DOE's mission.

During her doctoral studies (1992 - 1996) Nelson was already involved in the genome sequencing of various microbial species.

Reconstruction of its genome using MaxBin (click here) demonstrated that it grew on small organic molecules released by primary degrader in the microbial community.

Reconstructing genomes from metagenomics data provides a powerful way to understand what processes and interactions toccur in microbial communities.

The longest running continual training program in the Institute has been funded by the National Institutes of Allergy and Infectious Disease (NIAID), under the current Genome Center for Infectious Disease cooperative agreement (GCID), and its predecessor contracts, the Genome Sequencing Center for Infectious Disease (GSCID), and Microbial Sequencing Center (MSC).

With the number of published microbial genomes now in excess of 100, any new genome that is sequenced is likely to have a close relative available for comparison.

«Even though a microbial genome is one - thousandth the size of the human genome, the total number of microbial genes in [the human] body is much greater than human genes because you have so many different species,» says Weinstock.