Not exact matches
The
human body has more
microbial than
human cells, but this rich diversity
of micro-helpers that has evolved along with us is undergoing a rapid shift — one that may have very macro
health consequences
In this latest advance reported in PNAS, the Wyss team showed that the
human gut - on - a-chip's unique ability to co-culture intestinal cells with living microbes from the normal gut microbiome for an extended period
of time, up to two weeks, could allow breakthrough insights into how the
microbial communities that flourish inside our GI tracts contribute to
human health and disease.
Wherever we go,
microbial communities will faithfully follow, making this evidence
of the effects
of spaceflight on bacterial physiology relevant to
human health.
Two
of the largest efforts are the
Human Microbiome Project, funded by the National Institutes
of Health (See «Your
Microbial Menagerie,» page 4), and the European Union's Metagenomics
of the
Human Intestinal Tract.
But when placed in a closed environment, Komodo dragons interact with their surroundings much in the same way
humans do — at least on the
microbial level — and researchers are using this knowledge to help them understand the
health of animals in captivity.
«The more we know about the
microbial communities in a given environment, the more likely it is we can reshape them to improve environmental and
human health,» said senior author Rob Knight, PhD, professor
of pediatrics and computer science and engineering, and director
of the Center for Microbiome Innovation at UC San Diego.
Scientists are pushing to restore
human health in Western countries by changing our diet to restore the
microbial species lost over the evolution
of Western diet.
The findings illuminate the specialized roles played by key members
of the vast
microbial community living in the
human gut, and could inform the development
of tailored microbiota transplants to improve intestinal
health after antibiotic use or illness.
Despite the importance
of the skin ecosystem to
human health and well - being, we know very little about the forces that shape
microbial structure and composition in the skin environment.
A holistic understanding
of the role
of Earth's
microbial community and its genome — its microbiome — in the biosphere and in
human health is key to meeting many
of the challenges that face humanity in the twenty - first century, from energy to infection to agriculture.
«Our goal is to discover what
microbial communities exist in different parts
of the
human body and to explore how these communities change in the presence of health or disease,» said National Human Genome Research Institute Director, Francis S. Collins, M.D., Ph.D., co-chair of the Human Microbiome Project Implementation G
human body and to explore how these communities change in the presence
of health or disease,» said National
Human Genome Research Institute Director, Francis S. Collins, M.D., Ph.D., co-chair of the Human Microbiome Project Implementation G
Human Genome Research Institute Director, Francis S. Collins, M.D., Ph.D., co-chair
of the
Human Microbiome Project Implementation G
Human Microbiome Project Implementation Group.
Dr. Tang has had a long - standing interest and a demonstrated record
of productive multidisciplinary research in studying
microbial small molecules and their effects on
human health.
Professor Segal's research has two major directions 1) Gene regulation — using quantitative and computational models to understand how DNA sequence variation among
human individuals generates phenotypic diversity 2) Microbiome and Nutrition — understanding how the
microbial composition
of individuals affect their physiology and
health.
In addition, the results
of the current study can serve as a foundational dataset and resource for future investigations to understand interactions among
microbial communities, particularly those important to
human health and the environment.
The long - term goal
of such an effort is to be able to harness the power
of microbial communities to improve
human health and the
health of the planet.
«Microbes play a significant role in the
health of the digestive tract and many digestive diseases result when the
microbial environment is out
of balance,» said Griffin P. Rodgers, M.D., M.A.C.P., director
of the National Institute
of Diabetes and Digestive and Kidney Diseases (NIDDK), and co-chair
of the
Human Microbiome Project's Implementation Group.
Researchers are continuing to study the identities and activities
of our
microbial passengers and the connections between the
human microbiome,
health and disease.
Transmission
of commensal intestinal bacteria between
humans could promote
health by establishing, maintaining and replenishing
microbial diversity in the microbiota
of an individual.
The effect
of diet on the gluconeogenic capacity
of rat - kidney - cortex slices [5] Liver and kidney metabolism during prolonged starvation [6] Unrecognized Pandemic «Subclinical» Diabetes
of the Affluent Nations: Causes, Cost and Prevention [7] Carbohydrates and Immune Function [8] Overexpression
of glut1 and glut3 in stage I nonsmall cell lung carcinoma is Associated with poor survival [9] The in?uence
of diet on the mucin carbohydrates in the chick intestinal tract [10] Rat intestinal mucosal responses to a
microbial flora and different diets [12] Chronic Ethanol Induced Impairment
of Hepatic Glycosylation Machinery in Rat Is Independent
of Dietary Carbohydrate [13] Glycosylation in Cellular Mechanisms
of Health and Disease [14] Metabolic Aberrations Associated with Arginine Deficiency [15] Glycerol gluconeogenesis in fasting
humans
«One study published in
Microbial Ecology in
Health and Disease looked at the dietary influence
of various carbohydrates in vitro on the adherence
of Candida to
human epithelial cells.2 The study examined the effect
of various carbohydrates including fructose, galactose, glucose, maltose, sorbitol, and sucrose.
Didi Pershouse is the author
of The Ecology
of Care: medicine, agriculture, money, and the quiet power
of human and
microbial communities as well as Understanding Soil
Health and Watershed Function.
The Forum on
Microbial Threats hosted a public workshop in Washington, DC to consider the possible infectious disease impacts
of global climate change and extreme weather events on
human, animal, and plant
health, as well as their expected implications for global and national security.