Microbial metabolites are substances produced by tiny living organisms called microbes. These substances are a result of the metabolic processes happening within these microbes, and they can have various effects, such as participating in chemical reactions, providing nutrients, or even causing disease.
Full definition
«This study suggests that laboratory studies
of microbial metabolite processing can help understand the role of these microbes in carbon cycling in the environment.
By contrast, mice raised in the germ - free cages showed worse motor symptoms when they either were treated with
microbial metabolites called short - chain fatty acids or received fecal transplants of gut microbes from patients with Parkinson's disease.
In order to identify
possible microbial metabolites associated with ASD Kang and his colleagues looked for and compared the compounds in fecal samples from children with and without ASD.
Mice on higher calorie diets had increased oxidative stress, disturbed lipid metabolism, suppressed glycolysis and altered gut -
microbial metabolites compared to those on the calorie - restricted regimens.
Examples include imaging techniques ranging from confocal advances to cryotomography — which can resolve subcellular structure and reveal microbial cell function — and ways to monitor the production and exchange
of microbial metabolites.
The focus of this position will be to examine mechanistic links between
gut microbial metabolites and liver disease progression using a highly translational approach.
Microbial metabolites, short - chain fatty acids, restrain tissue bacterial load, chronic inflammation, and associated cancer in the colon of mice.Kim M. European Journal of Immunology
They also had reduced levels of
the microbial metabolites acetate and butyrate, which correlated with higher amounts of systemic inflammation (19).
Title: Genetic and microRNA regulation of
the microbial metabolite TMAO, a driver of cardiometabolic disease