He will also be responsible for product quality control, management of stock culture banks and
new microbial product development, product improvements and methodologies for determining impacts on environments.
Ru - Mend ® is a direct -
fed microbial product designed to enhance ruminal digestion and feed efficiency in ruminants.
Professor Bowles, who referred to the research in a panel discussion on «Nature's Marvellous Medicines» at the recent Royal Society Summer Science Exhibition, said: «We were measuring how flavonoids affected the production of inflammatory mediators by cells stimulated
by microbial products.
After
detecting microbial products or pro-inflammatory cytokines, immature dendritic cells transform into mature dendritic cells, which exhibit an exceptional capacity for T cell activation.
Commercial Microbial Products: Exploiting Beneficial Plant - Microbe Interaction — Pallavi, Plant - Microbe Interactions in Agro-Ecological Perspectives
While working on her PhD, she became fascinated by an exciting field of research opened by the discovery of Dropsophila Toll and the mammalian Toll - like receptors «as receptors
for microbial products.»
Structural damage to the gut is thought to contribute to this immune activation because of microbial translocation — the leakage of endotoxins and
other microbial products across the gastrointestinal barrier and into systemic circulation — but the precise mechanisms driving immune activation, and ways to alleviate among HIV - infected individuals is still not clear.
Circulating levels of... a marker of intestinal epithelial cell damage, were significantly elevated in the affected individuals and correlated with the immune responses to
microbial products...
«This work is an elegant example of how tuning of inflammatory circuits by linking diet to
microbial products can have a profound effect on an inflammatory disease in the joints.
However, in autoimmune disease, various environmental insults cause the tight junctions to become excessively permeable, enabling undigested food proteins, toxicants, and
microbial products to navigate across the gut barrier where they elicit immune reactions that can culminate in autoimmunity (2).