Not exact matches
Researchers leading a large, ongoing
study in women called VOICE that compares PrEP with pills to a vaginal
microbicide plan to revaluate the ethics of continuing to use a placebo control group given the new evidence of oral Truvada's powerful impact.
The largest
study ever conducted of a
microbicide designed to prevent HIV infection has resulted in yet another case of high hopes being dashed about a promising product.
That $ 90 million
study, financed by the U.S. National Institutes of Health (NIH), startled many in the field who, based on other failures of nonspecific
microbicides, had predicted the product would do nothing.
«This [set of
studies] was the last hope for
microbicides in many ways,» says Thomas Hope of Northwestern University's Feinberg School of Medicine in Chicago, Illinois.
Now a new monkey
study suggests that a
microbicide containing a compound that many investigators would consider old - fashioned may have the power to thwart the AIDS virus.
Today, most
microbicides in human
studies or on the drawing board contain anti-HIV drugs that cripple a critical viral enzyme.
Interim data from a parallel open - label
study of the ring called HOPE, led by the US National Institutes of Health - funded
Microbicide Trials Network (MTN), reported nearly identical results today at CROI.
Pilar received her PhD in 2017 at the Complutense University of Madrid, where she
studied immune cell dysfunction and hyperactivation in HIV / HCV coinfected patients, as well as the in vitro and in vivo activity of nanoparticles against HIV - 1 and HSV - 2 infections to prevent their transmission in humans as a topical
microbicide.
Results from an initial
study combining a
microbicide candidate and experimental vaccine are promising enough to at least keep Imperial College virologist Robin Shattock coming back for more in pursuing what could be a novel move in preventing HIV infection.