The phrase
"microbiome composition" refers to the types and amounts of microorganisms that live in and on our bodies. It includes the bacteria, viruses, fungi, and other microscopic organisms present in different parts of our body such as the gut, skin, or mouth. Each person has a unique
microbiome composition that can influence their health and well-being.
Full definition
We provide users with personalized nutrition and behavioral recommendations based on their personal health records and their specific
gut microbiome composition.
Objective To examine the associations of delivery mode and feeding method with infant intestinal
microbiome composition at approximately 6 weeks of life.
This «hygiene hypothesis» suggests that health risks not attributable to human genetics and behavior may stem from differences
in microbiome composition between individuals.»
While the UniFrac analyses we performed suggest independent associations
between microbiome composition and both delivery mode and feeding method, the substantial overlap between the communities defined by both factors suggests that there are other important drivers of microbiome community composition that remain to be identified in future analyses.
Last, Dr. Ece Mutlu presented this RUSH University Medical Center Study (which can also be read here) showing SCD dieters had greater intestinal bacterial diversity addition to having a
differing microbiome composition compared to controls.
Dr. Ece Mutlu presented this RUSH University Medical Center Study (which can also be read here) showing SCD dieters had greater intestinal bacterial diversity addition to having a differing
microbiome composition compared to controls.
Fecal microbiome composition and stability in 4 - to 8 - year old children is associated with dietary patterns and nutrient intake — Kirsten Berding — The Journal of Nutritional Biochemistry
Another study from Sweden even demonstrated that the
specific microbiome composition occurring in Alzheimer's patients induces the development of disease - specific amyloid - beta plaques, thereby establishing a direct functional link between the gut microbiome and Alzheimer's disease — at least in mice.
Next - generation sequencing methods can help illuminate specific compositional and functional features that underlie oral health and ECC, however, there are no population - based studies of the
oral microbiome composition and function in the context of ECC management — this represents a knowledge gap.
«With this study, we sought to characterize preschool - age children's
supragingival microbiome composition according to clinical statuses of health («caries - free»), «restored disease» and «non-restored» or «untreated» disease,» said Kimon Divaris.
Further comparisons with western microbiome data showed that the
Bantu microbiome composition falls on a spectrum between the BaAka and western populations.
Gut
Microbiome Composition Predicts Infection Risk during Chemotherapy in Children with Acute Lymphoblastic Leukemia — Hana Hakim — Clinical Infectious Diseases
Current pre-clinical efforts are focused on optimizing specific
microbiome compositions based on functional and phylogenetic information to inform the development of therapeutic candidates.
A new study which was published only last month revealed that Alzheimer patients display a different and less
diverse microbiome composition than healthy control subjects.
They also plan to evaluate whether colorectal
tumor microbiome composition can be assayed from stool samples, and if this data can also be used to predict the type of mutations present in the tumor cells.
«One thing this suggests is that maybe the reason it's not more effective is that people need both cranberries and a higher urine pH, or they need cranberries and appropriate inhabitants of their intestine, or the
right microbiome composition in their gut, for the cranberry part to work properly.»
Human gut microbiome
Gut microbiome composition in lean patients with NASH is associated with liver damage independent from caloric intake: a prospective pilot study — Sebastião Mauro Bezerra Duarte — Nutrition, Metabolism and Cardiovascular Diseases
However, the Weizmann researchers were surprised to discover that the host's genetics play a very minor role in
determining microbiome composition — only accounting for about 2 % of the variation between populations.
We observed an association between feeding method and
microbiome composition that remained statistically significant even after adjusting for delivery mode.
Overall stool microbiome community composition was characterized using generalized UniFrac analysis.30 Controlling for the effects of feeding method, delivery mode was strongly associated with infant gut
microbiome composition (P <.001; Q <.001)(Figure 1A).
Conclusions and Relevance The infant intestinal microbiome at approximately 6 weeks of age is significantly associated with both delivery mode and feeding method, and the supplementation of breast milk feeding with formula is associated with
a microbiome composition that resembles that of infants who are exclusively formula fed.
«We were curious if the transmission of microbes is enough to explain the variation that we see in
the microbiome composition among individual fish.»
«Women with polycystic ovary syndrome have less bacterial diversity in gut: Study finds elevated testosterone levels in women linked to changes in
microbiome composition.»
«Given that
the microbiome composition and diversity change over time, it is tempting to speculate that the blood - brain barrier integrity also may fluctuate depending on the microbiome.
The scientists analyzing this data concluded that diet and lifestyle are by far the most dominant factors shaping
our microbiome composition.
In addition to genetic data and
microbiome composition, the information collected for each study participant included dietary habits, lifestyle, medications and additional measurements.
Her work combines fundamental innate immunology with molecular biology and she has reported extensively on the impact of innate immunity in infection, autoimmunity, cancer,
microbiome composition and metabolic disorders.
Protocol: Wisconsin microbiome study, a cross-sectional investigation of dietary fibre,
microbiome composition and antibiotic - resistant organisms: rationale and methods — Shoshannah Eggers — BMJ Journal
The connection between a host's
microbiome composition and its resulting behavior is known as the «microbiota - gut - brain axis.»
The PC3 vs. PC2 plot (panel b) illustrates the differences in
microbiome composition that exist among individual samples.
Second, it implies that dietary and / or host genetic differences in ancient populations may be reflected in differences in gut
microbiome composition and it confirms that the two indigenous cultures were indeed distinct.