The gut
microbiome influences the immune system and inflammation in a profound way.
This project will continue the work to understand what makes a high - quality neoantigen and how
the microbiome influences how the immune system recognizes it, with the goal of developing a method for creating vaccines to treat pancreatic cancers.
The Intestinal
Microbiome Influences the Response of Cancers to PD - 1 — Based Immunotherapy: Might Fecal Transplantation Become Part of Cancer Therapy?
Jansson is also leading an investigation funded by the Office of Naval Research on how the gut
microbiome influences the brain.
The vaginal
microbiome influences health and disease of the female reproductive tract, and there is emerging evidence of the involvement of vaginal microbiota in the risk of persistent HPV and subsequent development of cervical cancer.
An organism's
microbiome influences the development and health of those animals and plants, whereas the microbiome of soil and buildings influence organisms that reside in those non-living environments.
Warinner and colleague, Cecil M. Lewis, Jr., co-direct OU's Laboratories of Molecular Anthropology and Microbiome Research and the research focused on reconstructing the ancestral human oral and gut microbiome, addressing questions concerning how the relationship between humans and microbes has changed through time and how
our microbiomes influence health and disease in diverse populations, both today and in the past.
Not exact matches
Some small studies have suggested that synbiotics could provide benefits to a range of other conditions
influenced by the gut
microbiome as well, including obesity, diabetes, and non-alcoholic fatty liver disease, but larger - scale clinical trials focusing on each of those conditions are needed.
There are several pathways where diet may
influence intestinal inflammation, such as direct dietary antigens, altering the gut
microbiome, and affecting gastrointestinal permeability.
The Shedd Aquarium
Microbiome Project is the world's first comprehensive look at
microbiomes in a controlled aquarium ecosystem and how they
influence animal health.
The human
microbiome is the composite of genes of the microorganisms (microbiota) living in and on the human body that
influence the health and development of the host (1).
How did these interventions
influence the health of the third, silent, and invisible member of my daughter's birth that I hadn't included in her birth plan — her
microbiome?
The contribution of bacteria through vaginal delivery followed by exclusive breastfeeding promotes specific microbial profiles that facilitate optimal nutrient metabolism and early systemic immune training.23 The potential short - and long - term effects of perturbations of the gut
microbiome of infancy, as
influenced by operative delivery or formula feeding, are beginning to be examined.
The potential «eavesdropping» of bacteria on human hormones during pregnancy and labor led me to wonder how the use of synthetic hormones such as Pitocin, especially during stalled labor, might
influence the
microbiome and overall infant health.
However, it does suggest that the process of labor, perhaps the hormonal or other physiological changes, may
influence the
microbiome.
Several variables such as length of time in labor or how far labor progressed, antibiotic use, natural vs. artificial rupture of membranes, and / or other interventions that may
influence the
microbiome were also not examined [10].
Many other factors surrounding birth may
influence the infant
microbiome.
A research study released in May, 2017 found that the bacteria found in mother's milk and areolar skin seed the infant gut and profoundly
influence the development of infant
microbiome.
Every health professional tending to pregnant women should be aware of the importance of the
microbiome and supporting a healthy
microbiome because that is what is going to
influence health across a life - span.
Animal studies have started to show that the
microbiome, from its staging ground in the bowel, can
influence the development of its host's brain.
The researchers explain that a high fat diet boosts cell metabolism, including the release of inflammatory chemicals, as well as
influencing the gut
microbiome and associated immunity.
Many common diseases may be
influenced by the
microbiome, because microbes control many of the body's essential chemical processes: They predigest our food, chemically modify the pills we take, shape our immune system responses, and repel infectious invaders.
The
influence of the «
microbiome» on our health has become a hot topic in recent years but privacy issues are now being raised
The findings highlight «the potential of the
microbiome to
influence human disease,» says Lindsay Kalan, a biochemist at the University of Wisconsin — Madison.
Changes in the composition and activity of the gut
microbiome in early life can
influence the immune system and these changes might indirectly lead to changes in asthma later in life,» said Dr. Anke Maitland - van der Zee, senior author of the study.
The Duke medical researchers and ecologists who have joined that project hope to identify which species flourish in early stages of the human
microbiome, how they are
influenced by the consumption of breast milk, and what role they play in critical diseases affecting infants as well as in chronic diseases that occur later in life.
«From mice, clues to
microbiome's
influence on metabolic disease.»
«These are the best - done and largest assessments of how the
microbiome may
influence therapeutic outcome» from those drugs, says immunotherapy researcher Jeffrey Weber of New York University in New York City, who was not involved in the studies.
Their survey is part of a growing push to look beyond the bacteria that make up the much - discussed
microbiome to find other microbes that naturally inhabit the human body and may
influence health and disease.
Our behavior can
influence the
microbiome right back.
The
microbiome churns out the mood -
influencing neurotransmitters serotonin, norepinephrine and dopamine.
More provocatively, insect studies have shown that having non-matching
microbiomes can prevent individuals of the same species from producing viable offspring, thus
influencing the evolution of their host insect species.
Microbiomes are
influenced by diet and lifestyle, and are vital to a person's health, as they can protect against disease.
As mounting evidence continues to suggest that the makeup of a person's gut
microbiome may
influence his or her risk for obesity, Loomba and team began to wonder if the gut
microbiome might also be linked to obesity - associated liver disease.
A gene associated with risk for Alzheimer's disease
influences the gut
microbiome of mice, potentiating a novel treatment strategy (Ishita Parikh, abstract 476.02, see attached summary).
Lead author Ana Maria Crissien, M.D., and her colleagues from Scripps Clinic and Green Hospital, believe that factors
influencing the human
microbiome at birth and early childhood can
influence the
microbiome years later.
Fiumera works in vivo with fruit flies while Mahler works in vitro using a 3 - D cell - culture model of the gastrointestinal (GI) tract to understand how ingesting nanoparticles
influences glucose processing and the gut
microbiome.
«How bacteria in the gut
influence neurodegenerative disorders: Understanding the role of the
microbiome may lead to better treatments for Parkinson's, Alzheimer's.»
Researchers demonstrate for the first time that the immune system
influences the skin
microbiome.
«Since we found previously that the gut
microbiome — the communities of bacteria and other microbes living there — can
influence liver disease risk, we wondered what effect gastric acid suppression might have on the progression of chronic liver disease.
Researchers from the Perelman School of Medicine at the University of Pennsylvania demonstrate for the first time that the immune system
influences the skin
microbiome.
Factors
influencing susceptibility and resilience to developing PTSD are not yet fully understood, and identifying and understanding all these contributing factors could in future contribute to better treatments, especially since the
microbiome can easily be altered with the use of prebiotics (non-digestible food substances), probiotics (live, beneficial microorganisms), and synbiotics (a combination of probiotics and prebiotics), or dietary interventions.»
PHILADELPHIA — Researchers from the Perelman School of Medicine at the University of Pennsylvania demonstrate for the first time that the immune system
influences the skin
microbiome.
This is evidence that a person's genes can
influence the gut
microbiome's composition and in turn can shape the individual's phenotype.
Recent work by Gordon's group, for example, demonstrates that the commensal gut
microbiome of an individual
influences the efficiency of energy harvesting from ingested foodstuffs and, as a result, can directly
influence the extent of weight gain associated with food consumption (Turnbaugh et al, 2006).
The present study was designed as a way to understand how human to human contact
influences the skin
microbiome, since contact has long been acknowledged as a major dispersal vector for skin bacterial communities (Hamburger, 1947; Pittet et al., 2006).
Skin
Microbiomes of California Terrestrial Salamanders Are
Influenced by Habitat More Than Host Phylogeny — Alicia K. Bird — Frontiers in Microbiology
Microbiomes should be part of every study in which scientists are studying the performance of animals, plants, people, oceans or other ecosystems, because microbes have a major
influence on all aspects of the planet.
In this study, we used ribosomal RNA gene sequencing to identify the zooxanthellae, bacteria and archaea associated with healthy and yellow band diseased (YBD) colonies in the Media Luna reef of La Parguera, Puerto Rico, in order to examine the
influence of YBD on the Montastraea faveolata
microbiome.
Two recent Kavli Foundation spotlights highlighted the
microbiome's powerful
influence on the brain — which affects our emotions, our thoughts and even our memory — as well as how new knowledge about microbes is informing the next missions to search for life in our solar system.