Gastrointestinal health and
the microbiota affect the entire body.
June 20, 2016
Microbiota affect the rate of transplant acceptance and rejection Researchers from the University of Chicago have shown that microbiota — the bacteria, viruses and other microbes living on the skin and in the digestive system — play an important role in the body's ability to accept transplanted skin and other organs.
«Can chemicals produced by gut
microbiota affect children with autism?.»
«Among other factors we will be investigating is whether an individual's
microbiota affects the risk of contracting cholera, information that could help us better understand risk factors for the disease.»
In a recent paper in the journal Trends in Ecology and Evolution, Shapira, who studies the gut microbes of the nematode C. elegans, reviews evidence that demonstrates how
microbiotas affect and contribute to host evolution, either by evolving along with the host, or by stepping in at critical moments to help the host adapt to a new environmental challenge.
Preterm infant gut
microbiota affects intestinal epithelial development in a humanized microbiome gnotobiotic mouse model.
Not exact matches
61 The distinction between exclusive breastfeeding and partial breastfeeding in the analyses of the association between breastfeeding and the risk for childhood leukemia is essential given that the addition of infant formula, together with breast milk or instead of it, changes the infant's gut
microbiota,
affecting the immunology of the infant.62, 63 Thus, misclassification might weaken the association between breastfeeding and lower risk for childhood leukemia.
As noted by Dr. Vicki Ellingrod — the Chair of this session, «Current state - of - the - art research in both animal models as well as humans point to the link between the gut
microbiota and mood and anxiety models, as well as the potential for psychiatric medications to directly
affect the gut microbiome.»
In addition, cohousing coprophagic mice harboring transplanted
microbiota from discordant pairs provides an opportunity to determine which bacterial taxa invade the gut communities of cage mates, how invasion correlates with host phenotypes, and how invasion and microbial niche are
affected by human diets.
Chassaing and Gewirtz hypothesized that emulsifiers might
affect the gut
microbiota to promote these inflammatory diseases and designed experiments in mice to test this possibility.
Viennois and Chassaing hypothesized that emulsifiers might
affect the gut
microbiota in a way that promotes colorectal cancer.
GWI exposures alter the microbiome (i.e., bacterial content in the gut), and the
affected microbiota then produce endotoxins, which pass through a thinned lining of the gut (i.e., leaky gut) and into the blood where they circulate throughout the body.
Modern changes in dietary habits, particularly the consumption of processed foods lacking fiber, are believed to
affect microbiota and contribute to the increase of chronic inflammatory disease, including metabolic syndrome.
We will review recent data showing how fiber differences between GB diets and purified diets can significantly influence gut health and
microbiota, which itself can
affect metabolic disease development.
Fructose liquid and solid formulations differently
affect gut integrity,
microbiota composition and related liver toxicity: a comparative in vivo study — Raffaella Mastrocola — Journal of Nutritional Biochemistry
Periodontal pathogenic bacteria, Aggregatibacter actinomycetemcomitans
affect non-alcoholic fatty liver disease by altering gut
microbiota and glucose metabolism — Rina Komazaki — Scientific Reports
«The use of antibiotics should be considered as an important element
affecting microbiota composition.
Recent research has revealed many aspects of our health that are
affected by intestinal
microbiota.
Here we demonstrate through metagenomic and biochemical analyses that these changes
affect the metabolic potential of the mouse gut
microbiota.
So the destruction of natural habitats and urbanization not only
affects the health of the environment, but it also
affects our health and wellness by removing healthy colonizing
microbiota.»
We sometimes don't think about things like sleep or stress being able to
affect the
microbiota, but they all feed in together and have an effect.
And so that's why this can be a bit messy is because it's not just this linear, one input to one output, but you have your calories and you have the type of calories, you have your sleep, you have your stress, and these things have all been shown to also
affect the
microbiota.
It turns out that these same factors also
affect the
microbiota on our skin and protecting it may be just as important!
Gastrointestinal ailments are frequently associated with anxiety and imbalanced mood, and many researchers theorize that
affected persons could alleviate symptoms simply by balancing the gut
microbiota with more beneficial bacteria.
CONCLUSION: Indomethacin potentiates barrier dysfunction and EC injury induced by gluten,
affects systemic IFN - gamma production and the host response to intestinal
microbiota antigens in HLA - DQ8 / HCD4 mice.
Growing evidence suggests that low - fiber diets may adversely
affect the gut
microbiota, contributing to the development of many chronic lifestyle diseases.
What's more, this association seems to be
affected by changes in the gut
microbiota caused by diet.
«Emerging research suggests that [curcumin] could
affect the gut
microbiota, which has been linked to several chronic diseases,» the study authors write.
The long - term use of proton pump inhibitors (PPIs) and H2 - antagonists, as well as atrophic gastritis,
affects the composition of the gastric
microbiota; this is not surprising, considering that gastric
microbiota depends on gastric acid secretion.
Multiple factors may
affect the gut
microbiota.
GF mice have been shown to have increased plasma tryptophan concentrations, 47, 48 which can be normalized following post-weaning colonization.47 Resident gut bacteria can utilize tryptophan for growth229 and in some cases, production of indole, 230, 231 or serotonin (reviewed by O'Mahony and colleagues95), while the
microbiota might also
affect tryptophan availability by influencing host enzymes responsible for its degradation.47 By limiting the availability of tryptophan for serotonin production in the CNS (EC - derived serotonin does not cross the BBB), the gut
microbiota could influence serotonergic neurotransmission.95 In vulnerable populations, reducing the circulating concentrations of tryptophan has been shown to
affect mood, and to reinstate depressive symptoms in patients who have successfully responded to selective serotonin reuptake inhibitors.232, 233 The gut
microbiota could also influence the production of both neuroprotective and neurotoxic components of the kynurenine pathway.224
However, some studies have shown that they can negatively
affect the gut
microbiota.
It is now thought that, through this pathway,
microbiota can
affect behaviour and modulate brain plasticity and cognitive function.
While numerous antimicrobials can
affect the delicate balance of the gut flora, broad spectrum medications like amoxicillin, minocycline, doxycycline, and clarithromycin (just to name a few) pose the greatest risk of destroying healthy intestinal
microbiota allowing yeast to flourish.
So red meat
affects both your gut
microbiota and your health, and gut microbes appear to be playing a role in determining HOW red meat
affects your health.
Capsaicin may also defend against heart disease and possesses antimicrobial properties that may indirectly
affect the host by altering the gut
microbiota.