A review of seven studies found that probiotics have little effect on the gut
microbiota composition of healthy people.
Effect of live yeast Saccharomyces cerevisiae (Actisaf Sc 47) supplementation on the performance and hindgut
microbiota composition of weanling pigs — T. G. Kiros — Scientific Reports
Jeroen Raes (VIB / VUB / KU Leuven): «Our research has given us a tremendous amount of new insight into
the microbiota composition of normal people like you and me.
Not exact matches
In the most recent
of these reports (in the latest issue
of Science), Dr. Jennifer Wargo, a surgeon and research scientist at M.D. Anderson, along with several dozen colleagues at other institutions, reveal that the
composition of a patient's gut
microbiota can significantly influence whether he or she responds to an immune checkpoint inhibitor — the type
of cancer immunotherapy that releases the emergency brakes in the car analogy above.
Stress plays a huge role in gut health, altering the
composition of the gastrointestinal
microbiota and likewise, an unhealthy diversity
of bacteria can impact emotional behaviour and exacerbate our stress response.
Recent findings show that the mother's gut
microbiota has an important impact upon the microbial
composition of the milk and its health supporting qualities.
The species
composition of the human intestinal
microbiota differs between particle - associated and liquid phase communities.
There are other components in breast milk known to shape the
composition of the gut
microbiota.
A small study
of 60 randomly selected 7 - year - old children, 31 delivered by cesarean and 29 delivered vaginally, assessed
microbiota composition by determining fecal
microbiota profiles using culture - independent fluorescent in situ hybridization and compared the respective effects
of delivery mode on gut
microbiota (12).
Our objective was to evaluate the relative associations
of delivery and feeding modes with the
composition of the intestinal
microbiota at approximately 6 weeks
of age in 102 infants from a US pregnancy cohort study.
A previous study highlighted infant nutrition as a major contributor to the early
microbiota composition and function, with cessation
of breastfeeding contributing the most fundamental shift in the
composition of bacteria.8 A longitudinal study with more participants would allow us to determine the temporal dynamics
of the effects
of feeding practices and changes therein, as well as the persistence
of the effects
of both feeding and delivery mode later in infancy.
Over 100 different oligosaccharides have been identified in the human colon, and recent research has shown that variations in the oligosaccharides within the mucus are associated with variations in the
composition of the gut
microbiota.
This may be one way in which the body tries to tailor the
composition of the
microbiota in different parts
of the gastrointestinal tract.
In a recent study published in the journal Nature Communications on 17 September, John Baines, Saleh Ibrahim and their colleagues
of the Inflammation Research Excellence Cluster show that
composition of skin
microbiota is controlled by the host genome and that skin bacteria may have a greater influence on inflammatory diseases than previously thought.
«That is why we have followed the
composition of the intestinal
microbiota of patients using modern DNA sequencing methods over a period
of up to three months after treatment.»
Changes in the
composition of the gut
microbiota are seen in many human diseases such IBD, a chronic, lifelong inflammatory disorder that includes Crohn's disease and ulcerative colitis.
The article, «Effects
of weight loss while feeding a moderate - protein, high - fiber diet on body
composition, voluntary physical activity, and fecal
microbiota of overweight cats,» is published in the American Journal
of Veterinary Research.
«Remarkably, our findings suggest that
composition of the gut
microbiota influence and alter central carbon metabolism in a genotype independent manner.
We know that a well - balanced gut
microbiota is critical for maintaining general health, and alterations in the
composition of gut
microbiota have been linked to a range
of disorders.»
«And we have evidence that the
composition of the gut
microbiota is controlled by the genomes
of the mice.
We're trying to find the genes that control the
composition of the gut
microbiota and (dictate) host phenotype.»
Mothers known as «non-secretors» have a non-functional fucosyltransferase 2 (FUT2) gene, which alters the
composition of their breast milk sugars and changes how the microbial community, or
microbiota,
of their infants» guts develop.
Rather, it conveys the subtle and elegant choreography
of one part
of the human microbiome: The relationships between the mothers» genetics, the
composition of her breast milk and the development
of her infant's gut
microbiota.
Thus, specific properties
of bioactive foods may be used to target and improve the
microbiota composition and overall health.
By injecting daily a low dose
of a large spectrum antibiotic they were able to reverse the effects
of high fat diet on the
microbiota composition.
But other research has indicated that various stressors can alter the
composition of the gut
microbiota.
A deep global analysis
of the gut
microbiota composition was done by phylogenetic microarray analysis using a Human Intestinal Tract Chip (HITChip), an analytical device designed specifically for studying gut bacteria.
The effect is thought to be mediated by the intestinal microbes, since antibiotics in animal studies has been found to change the
composition of the intestinal
microbiota and reduce biodiversity.
The results showed that children's intestinal
microbiota composition clearly reflected the use
of antibiotics.
Young and colleagues used DNA sequencing to study the
composition and structure
of fecal
microbiota (bacteria) in stool samples from 14 patients before and two to four weeks after fecal transplant.
Analyzing the
composition of the gut
microbiota, investigators found that Proteobacteria and Bacteroidetes persisted after the broad - spectrum antibiotic treatment in the Western diet - fed FXR KO mice.
In order to find out which bacterial species may be present in the air and on the surfaces inside spacecraft and how the
composition of the
microbiota may change during human habitation, a crew
of six male «Marsonauts» lived inside a mock - up spacecraft, located in Moscow, from 3rd June 2010 to 5th November 2011.
Emulsifiers, which are added to most processed foods to aid texture and extend shelf life, can alter the gut
microbiota composition and localization to induce intestinal inflammation that promotes the development
of inflammatory bowel disease and metabolic syndrome, new research shows.
Researchers observed that consuming emulsifiers drastically changed the species
composition of the gut
microbiota in a manner that made it more pro-inflammatory, creating a niche favoring cancer induction and development.
They observed that emulsifier consumption changed the species
composition of the gut
microbiota and did so in a manner that made it more pro-inflammatory.
Low - grade inflammation, a condition more prevalent than IBD, was shown to be associated with altered gut
microbiota composition and metabolic disease and is observed in many cases
of colorectal cancer.
In research published last year, Raoult and others showed that the vulnerable subgroups could be predicted by the
composition of their gut
microbiota prior to antibiotic treatment.
We learned that the immune system acts as a normalizer
of the gut
microbiota composition.»
Although the patient's residual colonic
microbiota, prior to therapy was deficient in members
of the bacterial divisions - Firmicutes and Bacteriodetes, transplantation had a dramatic impact on the
composition of the patient's gut
microbiota.
Review: Influence
of Altered Gut
Microbiota Composition on Aging and Aging - Related Diseases — Jeonghyun Choi — Journal
of Lifestyle Medicine
Early fecal
microbiota composition in children who later develop celiac disease and associated autoimmunity — Anniina Rintala — Scandinavian Journal
of Gastroenterology
OBJECTIVES We aimed at evaluating the
composition of the gut
microbiota in adult patients with T1DM and T2DM and establishing a link between data obtained from microbiological testing and the patients» clinical data.
«We know that antibiotics are major risk factors for C. diff infection because they alter the gut
microbiota, or
composition of bacteria in the gut, by eliminating the bacteria that are normally there,» says Casey Theriot, assistant professor
of infectious disease at NC State and corresponding author
of a paper describing the research.
New deep sequencing methods provide a convenient platform for characterizing the
composition of the human
microbiota [4, 7, 8, 13, 15 — 19].
The
microbiota, which evolved over tens
of thousands
of years alongside their human hosts, constitutes a complex and diverse community whose exact
composition varies from person to person.
Physiological Translocation
of Lactic Acid Bacteria during Pregnancy Contributes to the
Composition of the Milk
Microbiota in Mice.
Recently, also the
composition of gut
microbiota has shown to be associated with energy balance, the risk
of insulin resistance and diabetes, potentially via changes
of the FA metabolism or via release
of gut - derived hormones (56).
Genetic ablation
of Cyp8b1 preserves host metabolic function by repressing steatohepatitis and altering gut
microbiota composition — Jay V Patankar — American Journal
of Physiology — Endocrinology and Metabolism
While genetic and epigenetic factors play between the host organism and the
microbiota — determining which microbes successfully colonize the gut and other organs — the ultimate dictating force
of the
composition of an organism's microbiome is diet and environment.
Fructose liquid and solid formulations differently affect gut integrity,
microbiota composition and related liver toxicity: a comparative in vivo study — Raffaella Mastrocola — Journal
of Nutritional Biochemistry