A selection of content from the Gut
Microbiota for Health.
Humans rely on their native
microbiota for nutrition and resistance to colonization by pathogens [3 — 6]; furthermore, recent discoveries have shown that symbiotic microbes make essential contributions to the development, metabolism, and immune response of the host [7 — 10].
Biologists have studied the termite gut
microbiota for more than a century, but they have disagreed over one important question: How did termite gut bacteria evolve?
The importance of the intestinal
microbiota for human health has just recently been unfolded.
A Mother Takes Probiotics And Her Baby Benefits At the Gut
Microbiota for Health World Summit (March 2015), Dr. Esther Jiménez explains, Recent findings show...
Not exact matches
The PDF, Microbes Make the Cheese, A Report from the American Academy
for Microbiology explains: Cheese is created by orderly successions of microbial communities that produce compounds responsible
for cheese flavor... Each piece of cheese contains as many as 10,000,000,000 or 10 billion microbes... The added starter cultures dominate the cheese
microbiota, establishing conditions that select
for the next microorganisms that will be capable of thriving in the changing cheese matrix.
MACS is a great new term because it means «the main component of dietary fiber that serve as the primary metabolic input
for the gut
microbiota» aka fuel
for the microbiome.
Further, there may be particular groups of people who might be particularly prone to a poor diet [3](see here too) where the already discussed term «leaky gut» is also relevant (see here); also bringing in the idea of a role
for those trillions of wee beasties (the gut
microbiota) that call us home.
If we think of our
microbiota as pets (that live inside us), we can think of resistant starch as the special pet food that we must eat,
for those special RS foods to reach our colon to feed our «pets».
The rest is Inulin (not Insulin), which is not a carb, so doesn't contribute calories
for you, but does fee the
microbiota in your tummy.
The scientists hypothesised that the findings could provide new strategies
for treating type 2 diabetes and the illnesses linked to
microbiota imbalance.
«Targeted promotion of the active SCFA producers as ecosystem service providers via personalised nutrition may present a novel ecological approach
for manipulating the gut
microbiota to manage T2DM and potentially other dysbiosis - related diseases,» Zhao added.
Genetic testing to identify nutritional needs and digital models
for analysing food interactions with gut
microbiota.
Another way I say «thanks
for teaching me about gut
microbiota and extra virgin olive oil» is with food.
Breastmilk Contains More Than 700 Species of Bacteria Spanish researchers have traced the bacterial
microbiota map in breastmilk, which is often the main source of nourishment
for newborns.
«Ultimately, we would hope that future studies would form dietary guidelines
for breastfeeding mothers to promote healthy development of their infants» gut
microbiota,» Meyer added.
61 The distinction between exclusive breastfeeding and partial breastfeeding in the analyses of the association between breastfeeding and the risk
for childhood leukemia is essential given that the addition of infant formula, together with breast milk or instead of it, changes the infant's gut
microbiota, affecting the immunology of the infant.62, 63 Thus, misclassification might weaken the association between breastfeeding and lower risk
for childhood leukemia.
The researchers are also scrounging around
for proteins, which can linger 10 times as long as DNA in tartar and provide hints of
microbiota signatures.
The findings may not only lead to a novel diagnosis tool of PSC, they may also be the starting point
for developing
microbiota - based therapies.
Dr Luis Pedro Coelho, commented: «These findings suggest that dogs could be a better model
for nutrition studies than pigs or mice and we could potentially use data from dogs to study the impact of diet on gut
microbiota in humans, and humans could be a good model to study the nutrition of dogs.
The Wyss team believes the ability of the human gut - on - a-chip to culture the microbiome with human gut cells also holds promise
for the field of precision medicine, where a patient's own cells and gut
microbiota could one day be cultured inside a gut - on - a-chip
for testing different therapies and identifying an individualized treatment strategy.
It's a tremendously complicated field, which is why we've seen results all over the place when people look
for the relationship between
microbiota and obesity.
«So far, it has not been sufficiently tested whether and how successful fecal transplantation is
for the permanent settlement of
microbiota from a healthy donor to a patient,» said Alexander Loy of the Department of Microbiology and Ecosystem Research, University of Vienna.
«What all the studies have found is that these populations who are living a more traditional lifestyle are the best approximation
for our ancient
microbiota.
As noted by Dr. Vicki Ellingrod — the Chair of this session, «Current state - of - the - art research in both animal models as well as humans point to the link between the gut
microbiota and mood and anxiety models, as well as the potential
for psychiatric medications to directly affect the gut microbiome.»
«Among other factors we will be investigating is whether an individual's
microbiota affects the risk of contracting cholera, information that could help us better understand risk factors
for the disease.»
They compared the abundance of
microbiota in rats given continuous access to either a healthy diet or junk food with a group cycled between the two diets, healthy
for four days and junk
for three, over 16 weeks.
«A reduction in the diversity of the gut's
microbiota and a loss of some of the beneficial biota is clearly not a good thing
for health.»
«The study suggests certain gut
microbiota, including Ruminococcus and Blautia, may be promising targets
for future therapeutic strategies to treat metabolic disorders,» Professor Morris said.
Recipients of the exercised mouse
microbiota also had a higher proportion of microbes that produce butyrate, a short - chain fatty acid that promotes healthy intestinal cells, reduces inflammation and generates energy
for the host.
Given the importance of the
microbiota in our gut
for well - being, is antibacterial mouthwash a good idea?
We know that a well - balanced gut
microbiota is critical
for maintaining general health, and alterations in the composition of gut
microbiota have been linked to a range of disorders.»
Exposure to lead during early development can alter the the gut
microbiota, increasing the chances
for obesity in adulthood, researchers from the University of Michigan School of Public Health have found.
«We also found differences in the gut
microbiota composition between those children taking a disease - modifying drug
for their disease compared with those who were not.
«Fecal
microbiota transplantation has been very successful
for many patients with C. difficile infections, but we've never known why.
Studies show that if you alter your diet dramatically,
for instance by changing the proportion of fibres, proteins or fats, you will see relatively quick changes in your
microbiota.
People with primary depression,
for example, show alterations in the
microbiota.
At this stage, the
microbiota is greatly influenced by diet,
for example whether you are breastfed or not.
A new Journal of Internal Medicine article proposes that artificial intelligence tools, such as machine learning algorithms, have the potential
for building predictive models
for the diagnosis and treatment of diseases linked to imbalances in gut microbial communities, or
microbiota.
Ridaura et al. (1241214; see the Perspective by Walker and Parkhill) obtained uncultured fecal
microbiota from twin pairs discordant
for body mass and transplanted them into adult germ - free mice.
Separate groups of germfree mice were colonized with uncultured fecal
microbiota from each member of four twin pairs discordant
for obesity or with culture collections from an obese (Ob) or lean (Ln) co-twin.
Faecal
microbiota transplantation is an established treatment method
for severe antibiotic associated diarrhea where medical treatment has not cleared the infection.
We transplanted fecal
microbiota from adult female twin pairs discordant
for obesity into germ - free mice fed low - fat mouse chow, as well as diets representing different levels of saturated fat and fruit and vegetable consumption typical of the U.S. diet.
Twins discordant
for obesity provide an opportunity to examine interrelations between obesity and its associated metabolic disorders, diet, and the gut
microbiota.
After the faecal
microbiota transplantation therapy, the patient's
microbiota was followed
for a year.
Although GMCSF is mostly known
for its role in inflammation, Dr. Merad's laboratory discovered that GM - CSF is produced in the normal gut by specialized cells called innate lymphocyte cells (ILCs) in response to
microbiota signals.
For the authors, «this research is further evidence of the undeniable role
microbiota plays in autoimmune diseases, particularly in controlling the development of autoimmune diabetes.»
Next steps
for the team include identifying
microbiota metabolites whose levels are either significantly elevated or depleted during diseases such as IBD or cancer, to find disease - specific markers and explore possible roles
for these metabolites in disease progression.
In a retrospective, multicenter, longitudinal observational study, the response rates to fecal
microbiota transplantation as a treatment
for recurrent C. difficile infection were determined a 30 and 90 days, and adverse events were registered.
Researchers from Inserm, Paris Descartes University and the CNRS (French National Centre
for Scientific Research), through collaboration with teams from China and Sweden, have recently shown how
microbiota protects against the development of type 1 diabetes.