Dietary fiber is the indigestible portion of plant foods and has two main components: insoluble fiber (principally cellulose and lignin) and soluble fiber such as galacto - oligosaccharides and fructooligosaccharides (FOS), which are fermented by the gut
microbiota into short - chain fatty acids (SCFAs) acetate, propionate, and butyrate.
For example, 2013 saw studies showing that transplanting human fecal
microbiota into mice could induce obesity and its associated metabolic phenotypes, and human data from a controlled study suggesting the procedure could treat recurrent C. difficileinfection.
«Furthermore, because each particular macronutrient has the potential to be metabolized by
microbiota into unique metabolic signals, the greater the variety in signals, the greater the variety of responses possible.»
Not exact matches
In the first study, scientists transplanted fecal material from exercised and sedentary mice
into the colons of sedentary germ - free mice, which had been raised in a sterile facility and had no
microbiota of their own.
Ridaura et al. (1241214; see the Perspective by Walker and Parkhill) obtained uncultured fecal
microbiota from twin pairs discordant for body mass and transplanted them
into adult germ - free mice.
We transplanted fecal
microbiota from adult female twin pairs discordant for obesity
into germ - free mice fed low - fat mouse chow, as well as diets representing different levels of saturated fat and fruit and vegetable consumption typical of the U.S. diet.
Using fecal transplants, researchers transferred
microbiota from IBS patients with or without anxiety
into germ - free mice.
Then, these products can be parsed
into host - derived or
microbiota - derived metabolites.
When the team transferred
microbiota from a mouse with such dysfunctional ILC3s
into a completely germ - free mouse, the recipient animal was highly susceptible to infections when later exposed to harmful bacteria.
«We showed that the presence of the maternal gut
microbiota during late pregnancy blocked the passage of labeled antibodies from the circulation
into the brain parenchyma of the growing fetus,» says first author Dr. Viorica Braniste at the Department of Microbiology, Tumor and Cell Biology at Karolinska Institutet.
The study is important because it links diet to changes in the gut
microbiota as well as bile acid profile, opening the possibility that probiotics and bile acid receptor agonists may be useful for the prevention and treatment of hepatic inflammation and progression
into advanced liver diseases such as cancer.
So to study the
microbiota in Parkinson's disease, you need to take that
into account.
Jeroen Raes (VIB / VUB / KU Leuven): «Our research has given us a tremendous amount of new insight
into the
microbiota composition of normal people like you and me.
GWI exposures alter the microbiome (i.e., bacterial content in the gut), and the affected
microbiota then produce endotoxins, which pass through a thinned lining of the gut (i.e., leaky gut) and
into the blood where they circulate throughout the body.
For a control group comparison, the researchers also engrafted
microbiota from regular C57BL / 6 mice
into a separate group of pregnant, germ - free mice.
Of note today: non-exclusive breastfeeding increases the risk of HIV transmission via the alteration of gut microbiome / T - cell activation; Fasting altered the gut microbiome in beneficial ways but only in mice previously fed a high fat diet; An investigation
into new species of the honey and bumblebee gut commensal genus Gilliamella; Catfish development shapes gut microbial community structure independent of diet; A metagenomic analysis of the skin microbiome of the frog, Craugastor fitzingeri; The microbiome is altered during the bioremediation of herbicide contaminated soil; The impact of urban density on the soil microbiome; A randomized placebo controlled clinical trial of a
microbiota based drug for the prevention of Clostridium difficile Infection; and the virome of the Cuatro Ciénegas Basin of Mexico
To find out if pregnancy - associated microbes were causing this inflammation, the researchers transferred microbes from collected stool samples
into mice that contained no
microbiota of their own.
Scientists are excited by recent success with fecal
microbiota transplants (FMT), transfer of healthy fecal matter
into ailing patients, notably those with clostridium difficile (C. diff), a bacterial infection acquired after antibiotics, often in hospitals, that kills more than 15,000 people a year.
Comprehensive studies of changes in the resident intestinal
microbiota, host metabolism and immune system reactivity in T1D patients and cohorts at risk of T1D, as well as the correlation with clinical data, anti-islet antigen antibodies and HLA genotypes will enable identification of novel biomarkers and biosignatures, and insights
into the pathophysiology of the onset of T1D.
By introducing healthy and varied foods
into your everyday diet you can promote diversity within your gut
microbiota that will benefit you for a lifetime.
It combines Global Healing Center's best gut health products
into one incredibly effective program that will cleanse your gut, balance your
microbiota, and lay the foundation for abdominal comfort and peace.
In recent years, the importance of the gut
microbiota has come more clearly
into the picture as playing an important role in immune - related diseases, and even in regulating predisposition...
I attended a probiotic workshop at Yale last March and one of the presentations was given by Max Nueuwdrop, MD, PHD, an internist and endocrinologist from Amsterdam who went
into detail on the
microbiota and metabolism.
The great news is that by adding fermented veggies
into your foods, you are changing your gut health for better: «the composition of the gut
microbiota has been shown to differ in lean and obese humans and animals and to change rapidly in response to dietary factors.
However, chronic stress induces changes in permeability of the gastrointestinal tract barrier leading to release of
microbiota pro-inflammatory molecules
into the blood stream.»
What's more, transferring the
microbiota from one inbred mouse strain with distinct behavior
into another inbred (germ - free) strain is sufficient to transfer the host strain's behavior to the recipient7.
Rather, it passes
into the large intestine where it is broken down by the
microbiota.
Between the spores being present and the improved diet, the individual will go
into a state where they have the right
microbiota balance.
Parts II and III, Intestinal
microbiota, probiotics and mental health: from Metchnikoff to modern advances: Part II — contemporary contextual research and Intestinal
microbiota, probiotics and mental health: from Metchnikoff to modern advances: part III — convergence toward clinical trials, respectively, goes
into much
microbiota specificity and functionality for those desiring such.
All of these parts work together with trillions of bacteria (your
microbiota) to turn the food you eat
into the fuel your body needs, and the waste it does not.
These amino acids can subsequently be used by the
microbiota in the colon, or transported from the lumen
into the portal blood stream.
They are doing the direct research
into what makes your
microbiota happy, and have some amazing findings based in good science.