Restore the microbiome eating a whole foods diet which increases fiber to nudge favorable bacteroides, prevotella to fermicutes ratios and competitively crowd out and secure beneficial
microbiota using pre - and probiotics in live whole fermented foods.
Group research aims to study the relations between nutraceuticals, physical activity, intracellular mechanisms, gene expression and
microbiota using a translational approach to characterize the impact in the whole body of metabolic interactions studied in individual organs and tissues (in vitro / ex vivo: skeletal muscle, heart, bone, liver and kidney).
Regulation of vitamin D metabolism following disruption of
the microbiota using broad spectrum antibiotics — Stephanie A. Bora — The Journal of Nutritional Biochemistry
Not exact matches
How do the microbes within cheese interact with the natural
microbiota of the human gut and can cheese be
used to assist in maintaining a healthy gut
microbiota?
Using a «gnotobiotic mouse model» — where mice were «colonized with a synthetic human gut
microbiota composed of fully sequenced commensal bacteria» — Desai et al reported on the effects of different diets with different fibre content.
Use Healthy Fiber Sources: Fiber helps to grab up toxins in the digestive system and feeds the
microbiota.
A small study of 60 randomly selected 7 - year - old children, 31 delivered by cesarean and 29 delivered vaginally, assessed
microbiota composition by determining fecal
microbiota profiles
using culture - independent fluorescent in situ hybridization and compared the respective effects of delivery mode on gut
microbiota (12).
Her main research areas are Perinatal and human milk
microbiota and Characterization of probiotic bacteria and study of their
use in bacterial dysbiosis.
In collaboration with Synchrotron Oxford, the University of East Anglia and the University of California, the researchers,
using a commonly - found member of human gut
microbiota called Ruminococcus gnavus as a model organism identified carbohydrate binding modules with the ability to bind to mucus.
New research led by Dr Nathalie Juge at the Quadram Institute has identified some of the molecules
used to ensure bacteria in the gut
microbiota maintain healthy populations, in the correct locations in the body.
Prof. Severine Vermeire (KU Leuven / UZ Leuven): «In the future, gut bacteria may be
used to help identify PSC patients with a more or less aggressive disease, or patients that may benefit from
microbiota - based therapies, such as fecal
microbiota transplantation or targeted pre - and probiotics.»
Dr Luis Pedro Coelho, commented: «These findings suggest that dogs could be a better model for nutrition studies than pigs or mice and we could potentially
use data from dogs to study the impact of diet on gut
microbiota in humans, and humans could be a good model to study the nutrition of dogs.
The new
microbiota may trigger weight loss, says gastroenterologist Lee Kaplan of Massachusetts General Hospital, by sending chemical signals that cause the human host to burn more calories, which helps
use up the body's fat reserves.
Microscopic identification of the
microbiota in healthy (left) and inflamed intestine (right)
using specific gene probes.
A team led by gastroenterologists Sieglinde Angelberger and Walter Reinisch (Medical University Vienna) and microbiologists David Berry and Alexander Loy (University of Vienna) explored how a treatment called «fecal
microbiota transplantation» can be
used to support microbial recolonization of the gut of patients with chronic intestinal inflammation (ulcerative colitis).
«That is why we have followed the composition of the intestinal
microbiota of patients
using modern DNA sequencing methods over a period of up to three months after treatment.»
Researchers working on the Ribeirão Preto campus of the University of São Paulo (USP) in Brazil have discovered that a bacterium found in the
microbiota associated with leafcutter ant species Atta sexdens rubropilosa produces the so - called «trail pheromones,» i.e, the aromatic chemical compounds
used by the ants to lay a trail to their nest.
Azad is continuing her research in this general area, examining the
use of antibiotics and how it impacts the
microbiota of babies» guts.
«Also by studying how the gut
microbiota usually recover after cholera, we gain new ideas about how to manage severely disturbed microbial communities, ideas that can be
used to protect against diseases that often follow such disturbance, such as infections that commonly follow antibiotic
use.»
The studies were designed to isolate exercise - induced changes from other factors — such as diet or antibiotic
use — that might alter the intestinal
microbiota.
In this study that
used deep DNA sequencing of bacterial specific genes, the guts of both males and females exposed to lead had all of the similar complexity in
microbiota as those not exposed.
In addition to the office space, the lab currently contains a single studio apartment, which the researchers will
use to learn how to design living spaces that improve sleep quantity and quality in night - shift workers, and whether changes in these workers» circadian cycles influence their
microbiota.
If the researchers find this unique profile is linked to cancer development, they believe they could potentially
use the
microbiota in other sites such as the vagina or colon as a screening tool.
Using fecal transplants, researchers transferred
microbiota from IBS patients with or without anxiety into germ - free mice.
Thus, specific properties of bioactive foods may be
used to target and improve the
microbiota composition and overall health.
She explained that phages outnumber their bacterial prey by a factor of 10 to 1, and that they have been proposed as the agents of change in recipients of faecal
microbiota transplantations
used to treat resistant or recurring bowel disease.
The
use of antibiotics in early childhood interferes with normal development of the intestinal
microbiota, shows research conducted at the University of Helsinki.
To evaluate the panda gut
microbiota, Pang and colleagues
used a laboratory technique called 16S rRNA sequencing.
The
use of macrolides was associated with
microbiota features, which have previously been associated with obesity and metabolic diseases.
It also shows the potential in
using new tools to analyze existing interactions between gut
microbiota and probiotics.
«Antibiotic
use in early life disrupt normal gut
microbiota development.»
A deep global analysis of the gut
microbiota composition was done by phylogenetic microarray analysis
using a Human Intestinal Tract Chip (HITChip), an analytical device designed specifically for studying gut bacteria.
Researchers investigated how many courses of antibiotics the children had received in their lifetime and how the
use of antibiotics was reflected in their intestinal
microbiota.
This visual abstract represents the findings of Thevaranjan et al. who,
using young and old germ - free and conventional mice, demonstrate that age - related
microbiota changes drive intestinal permeability, age - associated inflammation, and decreased macrophage function.
«The results from the study can be
used to support initiatives that can be
used to help children develop a type of gut
microbiota, which is beneficial for the immune system and for the digestive system.
Scientists from INRA and Danone Nutricia Research have shown the effect of a fermented milk product containing probiotics on the gut
microbiota,
using a novel high resolution bioinformatics tool.
The results showed that children's intestinal
microbiota composition clearly reflected the
use of antibiotics.
Young and colleagues
used DNA sequencing to study the composition and structure of fecal
microbiota (bacteria) in stool samples from 14 patients before and two to four weeks after fecal transplant.
Macrolides appear to promote also the development of antibiotic resistance, as the resistance to these antibiotics was elevated in the
microbiota of children who had
used them.
A single treatment
using an optimized, targeted form of faecal
microbiota transplantation (FMT) produces sustained clinical and cognitive improvements, according to the results of a long - term follow - up of patients with liver cirrhosis and hepatic encephalopathy (HE) who had participated in a short - term study.
Liver cirrhosis is a leading cause of morbidity and mortality, with complications such as HE resulting in recurrent emergency hospitalizations, irreversible brain injury, and a poor prognosis.2 - 5 There is some evidence that HE patients have a reduced relative abundance of certain beneficial gut
microbiota (e.g. Lachnospiraceae and Ruminococcaceae) and an enrichment of potentially pathogenic Enterobacteriaceae ¬ - a microbial profile that has been linked to cognitive impairment and systemic inflammation in cirrhotic patients with HE.1 Faecal
microbiota transplants have been
used successfully to correct dysbiotic conditions such as recurrent Clostridium difficile and ulcerative colitis,6 - 8 and a preliminary report suggested that FMT may be promising in the management of HE.9
For future patients who are infected with harmful bacteria, it might be beneficial to promote the development of good gut
microbiota to indirectly kill harmful bacteria, instead of
using antibiotics.»
To test the impact of intestinal microbes on the metabolism of indomethacin, the team
used antibiotics to deplete the
microbiota, then compared metabolism in treated and control mice.
Dr Petra Schwendner, University of Edinburgh, corresponding author of the study said: «Until now, little was known about the influence of long - term confinement on the microorganisms that live inside habitats that may one day be
used to travel to other planets, and whether the structure of the
microbiota changes with time.
While a core
microbiota of the same bacteria was present in all areas of the mock - up spacecraft, the authors noticed specific bacterial signatures for each individual area, or module, indicating that — much like in other indoor environments — microbial presence is associated with human presence as well as the type of activity that an area is
used for.
«This means that the
microbiota - dependent response to ACT was successfully transferred between mice, and that modulation with specific antibiotics can be
used to increase ACT efficacy,» Facciabene said, confirming that this technique could be applied to control gut microbiome populations and improve ACT.
By
using antibiotics and
microbiota transplantation, the investigators showed that gut
microbiota plays a causal role in dietary CAP - induced protective phenotype against high - fat - diet - induced CLGI and obesity.
We are
using the most powerful and advanced techniques including metabolomics, transcriptomics, genomics and the analysis of the gut
microbiota to understand what effect, the Mediterranean style diet has on the population of over 65 years old» said prof. Claudio Franceschi, project coordinator from the University of Bologna, Italy.
The findings illuminate the specialized roles played by key members of the vast microbial community living in the human gut, and could inform the development of tailored
microbiota transplants to improve intestinal health after antibiotic
use or illness.
For example, many studies on human
microbiota identify species (or operational taxonomic units) and map evolutionary relationships
using the 16S ribosomal RNA gene.