Sentences with phrase «microcephaly associated»

To evaluate the ocular findings in infants with microcephaly associated with presumed intrauterine ZIKV infection in Salvador, Bahia, Brazil.

Objective To evaluate the ocular findings in infants with microcephaly associated with presumed intrauterine ZIKV infection in Salvador, Bahia, Brazil.

Based on that, we recommend using the term congenital Zika syndrome instead of microcephaly associated with Zika virus infection, which involves a spectrum of changes, including other neurological and fetal development manifestations.

Jennifer Fish (Huttner, MPG)-- «The evolution of neuronal progenitor cell division in mammals: the role of the abnormal spindle - like microcephaly associated (Aspm) protein and epithelial cell polarity» (2007)

Lahn and his colleagues looked at the abnormal spindle - like microcephaly associated (ASPM) gene, which scientists had previously identified as a key player in brain development.

Not exact matches

A 2006 study of 77 pregnant women infected with West Nile virus reported that two had infants with microcephaly, the birth defect lately associated with Zika that results in unusually small and damaged brains.

However, the mechanism of Zika virus - associated microcephaly remains unclear.

Brazil said on Friday the number of confirmed and suspected cases of microcephaly in Brazil associated with the Zika virus has risen to 5,131 from 4,976 a week earlier.

Take the gene ASPM, short for «abnormal spindle - like microcephaly - associated».

An association between Zika infections during pregnancy and the birth of babies with microcephaly (a birth defect in which an infant's brain does not develop properly resulting in a smaller than normal head) was first suggested by Brazilian physicians in August 2015, and in November microcephaly cases potentially associated with Zika started to be recorded; three months later WHO made its announcement.

In that timeframe — before Zika appeared in the United States — microcephaly, brain abnormalities or another Zika - associated birth defect appeared in just 3 out of every 1,000 live births.

Some of the severe manifestations and complications associated with Zika disease include fetal loss, microcephaly and other birth defects, and the potential for delayed mental and physical effects among infected babies born in apparent good health.

As of March 30, the CDC has reported 312 cases of the Zika virus in the United States and heightened its efforts in response to Zika and the cases of microcephaly and other neurological disorders associated with the virus.

The physical characteristic most associated with Zika infection is microcephaly, a birth defect in which the baby's brain does not develop properly resulting in a smaller than normal head.

The African strain has one pattern, whereas the Puerto Rican strain, which is closely related to the Brazilian strain that is associated with microcephaly, has another.

Zika was known for 60 years as a mild virus that appeared sporadically, but since 2007, two troubling shifts have taken place, Dye said: Zika virus now results in widespread outbreaks of hundreds or thousands of cases, and it is associated with neurological disorders like microcephaly and Guillain - Barre syndrome, a disorder in which the body's immune system attacks the nerves.

Cases of both Zika virus and microcephaly — the potentially related occurrence of babies born with small - sized heads and associated neurological complications — will continue to increase across the Americas, said a panel of public health experts at a 12 February news briefing at the AAAS Annual Meeting in Washington, D.C.

Not unsurprisingly given the fact that microcephaly has not been associated with dengue, the neurospheres survived much better than when infected with Zika and the brain organoids showed no reduction in growth when compared to the controls.

Aneuploidy is associated with a variety of diseases such as cancer and microcephaly.

In addition, the mechanism by which the ZIKV infection can cause fetal brain damage is not known, and some reports suggest that the virus is able to evade the normal immunoprotective responses of the placenta.15 Zika virus is not the only pathogen associated with neonate microcephaly.

Structural eye anomalies (in particular, microphthalmia and coloboma), cataracts, intraocular calcifications, and posterior ocular findings have been reported in infants with presumed and laboratory - confirmed prenatal ZIKV infection; however, posterior findings have been the most prevalent.21,25,28,33,35,36,41 - 43 Case series report chorioretinal atrophy, focal pigmentary mottling of the retina, and optic nerve atrophy / anomalies.28, 34,37,41 - 43,55 Series of 20 or more infants with presumed ZIKV - associated microcephaly report ocular findings in 24 % to 55 %.28, 33,42 In one study, testing for ZIKV IgM was performed in 24 of 40 infants (60 %) with microcephaly and the results were positive in the cerebrospinal fluid in 100 % of those tested.42 The proportion of infants with ocular lesions did not differ in those with and without testing.42 In that series, first trimester maternal infection and smaller head circumference significantly correlated with the presence of abnormal ocular findings.42

The FBDS phenotype has been reported in an infant with laboratory - confirmed ZIKV infection, 13 in a neuroimaging report documenting cranial bone collapse in infants born to mothers with suspected ZIKV infection during pregnancy, 14 and a recent case series of infants with probable ZIKV - associated microcephaly.38 In 3 of the largest case series reporting 35, 48, and 104 infants primarily with suspected congenital ZIKV infection, 33,37,38 approximately two - thirds of infants had severe microcephaly.

10:00 - 10:15 am: Unveiling microcephaly mechanisms associated with DNA repair disorders using induced pluripotent stem cells and cerebral organoids

Zecavati is a pediatric neurologist who treats children with microcephaly and can describe the neurologic signs and symptoms associated with microcephaly, including the various causes of microcephaly and how microcephaly affects a child's development and cognitive abilities.

Loss of function mutations in CTNNB1 have been reported in individuals with intellectual disability [MIM # 615075] associated with peripheral spasticity, microcephaly and central hypotonia, suggesting a recognisable phenotype associated with haploinsufficiency for this gene.

Eighty - five percent of the fetuses or infants with potentially Zika - associated birth defects in this report had brain abnormalities or microcephaly, with most having both microcephaly and specific brain abnormalities.

A recent increase in the prevalence of microcephaly in newborn infants and vision - threatening findings in these infants is likely associated with the rapid spread of ZIKV.

Eleven of these babies were diagnosed with microcephaly — an abnormally small head and brain — and other neurologic complications associated with Zika syndrome, the researchers reported.