Sentences with phrase «microcephaly at»

«Among infants of mothers exposed to Zika virus during pregnancy, the absence of microcephaly at birth does not rule out congenital Zika virus infection or the presence of Zika - related brain abnormalities,» according to a news release from the U.S. Centers for Disease Control and Prevention.

This prospective study was conducted in Campina Grande, the second largest city in the state of Paraíba, which has reported the second highest prevalence of microcephaly at birth in Brazil.

Not exact matches

In a study conducted in Brazil, 70 infants with microcephaly were examined at CAVIVER, a nongovernmental organization clinic and referral center dedicated to visually disabled children in Fortaleza.

Researchers at IRB Barcelona study CEP63, a gene that is mutated in Seckel Syndrome, a rare disease that causes microcephaly and growth defects.

«We've been seeing growing evidence of the association between Zika and congenital central nervous system malformations, not just microcephaly, since the first cases were picked up,» says Wim Van Bortel, senior expert on vector - borne diseases at the European Centre for Disease Prevention and Control in Solna, Sweden.

Lahn and his colleagues looked at the abnormal spindle - like microcephaly associated (ASPM) gene, which scientists had previously identified as a key player in brain development.

Wong: I can't put percentages on that yet, but I would say that although there are still plenty of people who believe that the original interpretation is correct, there are an increasing number of people who at least think that the hypothesis of pathology, like this microcephaly, has not yet been sufficiently ruled out.

Frieden, who is the second - longest serving CDC director in the agency's history, says his years at the helm were marked with successes that include affirming the link between Zika virus and microcephaly, helping beat back Ebola and supporting programs that promoted a drop in U.S. teen pregnancy numbers.

«As we learn more about the consequences of Zika infection, including the recent revelation that babies of Zika - infected mothers who had normal head sizes at birth have been diagnosed with microcephaly months later, it is vital that we know this enemy and remain vigilant in protecting ourselves,» Diaz concludes.

That state has seen at least 487 microcephaly cases so far this year, compared with an average of 10 cases annually between 2010 and 2014.

Maybe the virus did cause microcephaly before, scientists suggested, but at such low rates that no one noticed.

Researchers weren't sure why microcephaly suddenly became a complication of Zika infections, says Pei - Yong Shi, a virologist at the University of Texas Medical Branch at Galveston.

The money would be a 1 - year increase to bolster health services for at - risk or infected pregnant women and babies born with microcephaly.

Cases of both Zika virus and microcephaly — the potentially related occurrence of babies born with small - sized heads and associated neurological complications — will continue to increase across the Americas, said a panel of public health experts at a 12 February news briefing at the AAAS Annual Meeting in Washington, D.C.

In a paper published in Nature Communications, scientists at the Institute for Research in Biomedicine (IRB Barcelona) provide molecular details about Seckel Syndrome, a rare disease that causes microcephaly, or small brain, and growth delays.

«Studies of fetuses and babies with the telltale small brains and heads of microcephaly in Zika - affected areas have found abnormalities in the cortex, and Zika virus has been found in the fetal tissue,» says Guo - li Ming, M.D., Ph.D., a professor of neurology, neuroscience, and psychiatry and behavioral science at Johns Hopkins» Institute for Cell Engineering.

Petersen's remarks were among the strongest suggestions yet from a top CDC scientist that Zika infection during pregnancy can — at least in some cases — cause microcephaly, a condition in which infants are born with abnormally small heads and possibly brain damage.

Ganeshwaran H. Mochida, a pediatric neurologist and researcher at Boston Children's Hospital, explained in an interview that «microcephaly is not a single disease.»

«What we show is the first piece of evidence» consistent with the hypothesis that Zika infections cause microcephaly, said Hengli Tang, a virologist at Florida State University and another lead author.

But Peter Hotez, dean of the National School of Tropical Medicine at Baylor College of Medicine, said its findings offer «potentially important» new information about the link between Zika and microcephaly.

Strengthening the link between Zika virus and microcephaly, scientists at UC San Francisco have discovered that a protein the virus uses to infect skin cells and cause a rash is present also in stem cells of the developing human brain and retina.

There is a causal link between Zika infection and at least two serious diseases: microcephaly and Guillain - Barré Syndrome (GBS).

Lancaster and Knoblich published their work in Nature in 2013, at a time when microcephaly was still rare.

We have shown that the presence of extra centrosomes in proliferating embryonic neural stem cells is sufficient to impair brain development and culminates in microcephaly (small brains) at birth.

The 3 largest case series of infants with microcephaly also reporting congenital contractures found that, among 35, 48, and 52 infants with microcephaly and presumed congenital ZIKV infection, isolated clubfoot occurred in 14 %, 10.4 %, and 3.8 % and arthrogryposis in 11 %, 10.4 %, and 5.7 %, respectively.36 - 38 Among a series of 104 infants under clinical investigation, 7 (6.7 %) with presumed (5 infants) and laboratory - confirmed (2 infants) congenital ZIKV infection had arthrogryposis; 6 of these infants had a head circumference of at least 2 SD below the mean.41 All had bilateral congenital hip dislocation, which previously has been reported to occur in 30 % to 40 % of children with arthrogryposis of various etiologies and 3 of 7 had dislocation or partial dislocation of 1 or both knees.41, 57

If Zika is the cause of microcephaly (and at the moment this looks increasingly likely), then a more subtle interaction between virus, patient and environment is involved, rather than some new property arising within the virus due to mutation.

They have identified specific small RNAs from Zika virus that could impact brain development and lead to microcephaly, at least in mice.

We report the integration of transcriptome sequencing (RNA - seq), which surveys all mRNAs to reveal functional impacts of variants at the transcription level, into the gene discovery framework for a unique human disease, microcephaly - micromelia syndrome (MMS).

«Just because the baby doesn't have microcephaly doesn't mean they won't have vision issues or hearing issues,» added Dr. Jill Rabin, co-chief of ambulatory care in Women's Health Programs and PCAP Services at Northwell Health in New Hyde Park, N.Y. «Problems may not show up until the child is 4 years old.»

«The emergence of Zika virus in the Americas has coincided with increased reports of babies born with microcephaly,» said study author Dr. Heron Werner Jr., of the radiology department at Rio de Janeiro's Clinica de Diagnostico por Imagem.

Lyle R. Petersen, MD, director of vector - borne diseases at the CDC, told the New York Times earlier this week that the agency had found the Zika virus in four Brazilian babies; two died in the womb, and two had microcephaly and died shortly after birth.

Despite the fact that Zika puts pregnant women at risk for having babies with the severe birth defect microcephaly, Frieden acknowledged to reporters that they continue to run into apathy over the virus and that it can be difficult to get the public to want to change behavior.

The researchers add that it's possible some children born with Zika infections but without microcephaly could also be at risk for hearing problems, though this has not yet been determined.

In the analysis, Mariana Leal, of the Hospital Agamenon Magalhaes and the Federal University of Pernambuco in Brazil, and colleagues looked at 70 infants in Brazil who had been diagnosed with Zika - linked microcephaly.

Expectant mothers are most at risk because of Zika's known link to birth defects (especially microcephaly, where a baby's head is smaller than normal at birth).

The state has the second highest number of Zika infections in the country, behind New York, including at least 53 pregnant women, who are considered to be at greatest risk from the virus because it can cause microcephaly and other birth defects.