Sentences with phrase «microcephaly occurs»

Taking that child out of the calculation suggests that hearing loss in Zika - induced microcephaly occurs in about 6 percent of cases.

Not exact matches

Neither set of pups developed microcephaly, which Diamond says could be because the researchers infected the mothers so early during pregnancy that not much brain development had yet occurred.

They discovered the S139N swap caused the most severe clinical outcomes but they also note other modern Zika virus strains without this mutation (some occurring in the wild and others that were lab - made) could also cause mild microcephaly and other cellular harm to mice.

The 3 largest case series of infants with microcephaly also reporting congenital contractures found that, among 35, 48, and 52 infants with microcephaly and presumed congenital ZIKV infection, isolated clubfoot occurred in 14 %, 10.4 %, and 3.8 % and arthrogryposis in 11 %, 10.4 %, and 5.7 %, respectively.36 - 38 Among a series of 104 infants under clinical investigation, 7 (6.7 %) with presumed (5 infants) and laboratory - confirmed (2 infants) congenital ZIKV infection had arthrogryposis; 6 of these infants had a head circumference of at least 2 SD below the mean.41 All had bilateral congenital hip dislocation, which previously has been reported to occur in 30 % to 40 % of children with arthrogryposis of various etiologies and 3 of 7 had dislocation or partial dislocation of 1 or both knees.41, 57

The authors note their findings could downplay the frequency in which hearing loss occurs in children infected with Zika in the womb because they only tested children with microcephaly, which is characterized by an abnormally small head and in some cases brain damage.

The included birth defects were based primarily on case reports of outcomes occurring in association with Zika virus infection during pregnancy; there is more evidence for some of these birth defects than for others, and a causal link has not been established for all.5,10,12,21 - 27 Because much of the focus to date has been on microcephaly and brain abnormalities, data were summarized in 2 mutually exclusive categories: (1) brain abnormalities with or without microcephaly regardless of the presence of additional birth defects and (2) neural tube defects and other early brain malformations, eye abnormalities, and other consequences of central nervous system dysfunction among those without evident brain abnormalities or microcephaly.