Sentences with phrase «microcephaly which»

In humans, the virus causes a birth defect called microcephaly which means «small brain».

Not exact matches

One of the reasons it's been so troubling is that it's a cause of a serious birth defect called microcephaly, in which the head of babies whose mothers have been infected with Zika during pregnancy are abnormally small.

This appears to be the first US case of a baby born with microcephaly, a condition in which the brain is abnormally small, after having a Zika infection.

In April, the CDC confirmed that Zika is a cause of microcephaly, a condition in which the head is born abnormally small.

But Zika in pregnant women has recently been linked to a serious birth defect called microcephaly, in which a baby is born with a small head and brain.

The connection between Zika and microcephaly first came to light last fall in Brazil, which has now confirmed more than 1,800 cases of microcephaly that it considers to be related to Zika infection in the mothers.

Specifically, children develop a condition called microcephaly, which causes abnormally small heads and underdeveloped brains.

But health officials suspect it may be behind a surge in cases of microcephaly, a condition which causes babies to develop abnormally small brains and skulls — leading to permanent disability or death.

SAN FRANCISCO — Cell biologists are learning more about how the Zika virus disrupts brain cells to cause the birth defect microcephaly, in which a baby's brain and head are smaller than usual.

The strains currently circulating in the Western Hemisphere, which have been linked to microcephaly in infants and Guillain Barre syndrome in adults, are more closely related to the Asian lineage.

But in pregnant women, it's been linked to a birth defect called microcephaly, which leaves babies with...

Neither set of pups developed microcephaly, which Diamond says could be because the researchers infected the mothers so early during pregnancy that not much brain development had yet occurred.

Lahn and his colleagues looked at the abnormal spindle - like microcephaly associated (ASPM) gene, which scientists had previously identified as a key player in brain development.

Some suggested Flo was a diseased modern human, related to pygmies but suffering from a condition like microcephaly, which causes the brain and head to be pathologically small.

One in 150 babies in the U.S. is born with a congenital CMV infection, and of those, one in five suffers from complications, according to the CDC, which can include including hearing loss, vision loss, cerebral palsy, cognitive impairments and microcephaly.

Colombia's dramatic uptick in microcephaly cases follows one reported in Brazil, which, in 2015, experienced a ninefold increase in cases compared with the previous 14 years.

An association between Zika infections during pregnancy and the birth of babies with microcephaly (a birth defect in which an infant's brain does not develop properly resulting in a smaller than normal head) was first suggested by Brazilian physicians in August 2015, and in November microcephaly cases potentially associated with Zika started to be recorded; three months later WHO made its announcement.

The infection has been linked to microcephaly, a condition in which infants are born with unusually small heads and brain damage.

A furious debate ensued: the fossil discoverers classify the meter - tall hominin as part of a separate species that lived as recently as 12,000 years ago; others maintain it was a modern human who had microcephaly, in which the brain fails to reach normal size.

But the Brazilian government is now warning that the virus may be responsible for a dramatic increase in cases of microcephaly, a severe birth defect in which the brain fails to develop properly and the head is much smaller than normal.

To build their tool, Alison Galvani, from Yale University in New Haven, USA, and colleagues focused on the two known serious consequences of Zika infection: microcephaly, a condition in which children are born with a small brain causing mental impairment, and Guillain - Barré syndrome or GBS, a potentially fatal disease that can cause neural damage and paralysis.

The physical characteristic most associated with Zika infection is microcephaly, a birth defect in which the baby's brain does not develop properly resulting in a smaller than normal head.

In humans, Zika virus infection during pregnancy has been linked to a suite of birth defects including a condition known as microcephaly, which leaves babies with shrunken heads and brains (SN: 4/2/16, p. 26).

Genes involved in microcephaly, a condition in which patients have brains roughly the size of chimpanzee brains, directly control the levels of BRCA1 expression, he says.

The famous cancer gene BRCA1 may also play a role in neurodevelopmental disorders such as microcephaly (right), which causes small brain size.

The African strain has one pattern, whereas the Puerto Rican strain, which is closely related to the Brazilian strain that is associated with microcephaly, has another.

In both of these scenarios, neural stem cells, which are crucial for normal neural development, are lost, leading to microcephaly.

Zika was known for 60 years as a mild virus that appeared sporadically, but since 2007, two troubling shifts have taken place, Dye said: Zika virus now results in widespread outbreaks of hundreds or thousands of cases, and it is associated with neurological disorders like microcephaly and Guillain - Barre syndrome, a disorder in which the body's immune system attacks the nerves.

These results collectively suggest that neural stem cells need MSI1 to generate enough neurons for normal brain size, but the presence of MSI1 also increases the vulnerability of these cells to Zika infection, leading to the death of the population which ultimately results in microcephaly.

Roughly four in every 1000 babies are infected with cytomegalovirus (CMV), which can cause seizures and intellectual disability, as well as Zika - like symptoms including microcephaly.

Since 2016 thousands of children across South America have been born with microcephaly, which causes abnormally small heads, after their mothers became infected with the Zika virus during pregnancy.

The research could also lead to better diagnosis and treatment of diseases such as microcephaly and autism, which arise from a misfolded cortex, he says.

Studying a new type of pinhead - size, lab - grown brain made with technology first suggested by three high school students, Johns Hopkins researchers have confirmed a key way in which Zika virus causes microcephaly and other damage in fetal brains: by infecting specialized stem cells that build its outer layer, the cortex.

Petersen's remarks were among the strongest suggestions yet from a top CDC scientist that Zika infection during pregnancy can — at least in some cases — cause microcephaly, a condition in which infants are born with abnormally small heads and possibly brain damage.

Such techniques have the potential to enhance research into the origins of neurodevelopmental and neuropsychiatric disorders such as microcephaly, lissencephaly, autism and schizophrenia, which are thought to affect cell types not found in the mouse models that are often used to study such diseases.

U.S. researchers say they have discovered how the Zika virus can cause microcephaly, a rare birth defect in which babies are born with abnormally small heads and brain problems.

This condition, which can be caused by a number of infections, is known as microcephaly (My - kro - SEFF - uh - lee).

This prospective study was conducted in Campina Grande, the second largest city in the state of Paraíba, which has reported the second highest prevalence of microcephaly at birth in Brazil.

Based on that, we recommend using the term congenital Zika syndrome instead of microcephaly associated with Zika virus infection, which involves a spectrum of changes, including other neurological and fetal development manifestations.

The main birth defect attributed to Zika is microcephaly, a rare neurological condition in which an infant is born with a much smaller head — an effect of abnormal brain development.

In addition, the mechanism by which the ZIKV infection can cause fetal brain damage is not known, and some reports suggest that the virus is able to evade the normal immunoprotective responses of the placenta.15 Zika virus is not the only pathogen associated with neonate microcephaly.

The 3 largest case series of infants with microcephaly also reporting congenital contractures found that, among 35, 48, and 52 infants with microcephaly and presumed congenital ZIKV infection, isolated clubfoot occurred in 14 %, 10.4 %, and 3.8 % and arthrogryposis in 11 %, 10.4 %, and 5.7 %, respectively.36 - 38 Among a series of 104 infants under clinical investigation, 7 (6.7 %) with presumed (5 infants) and laboratory - confirmed (2 infants) congenital ZIKV infection had arthrogryposis; 6 of these infants had a head circumference of at least 2 SD below the mean.41 All had bilateral congenital hip dislocation, which previously has been reported to occur in 30 % to 40 % of children with arthrogryposis of various etiologies and 3 of 7 had dislocation or partial dislocation of 1 or both knees.41, 57

microcephaly A birth defect in which a baby is born with a head that is smaller than expected.

Faria et al show that samples from microcephaly cases are distributed around the evolutionary tree, which strongly argues against (although again can't absolutely disprove) this idea.

The authors note their findings could downplay the frequency in which hearing loss occurs in children infected with Zika in the womb because they only tested children with microcephaly, which is characterized by an abnormally small head and in some cases brain damage.

«Once it infects a human cell, the virus could interact with human enzymes to produce these small RNAs, which could in turn alter brain development and lead to microcephaly.»

We report the integration of transcriptome sequencing (RNA - seq), which surveys all mRNAs to reveal functional impacts of variants at the transcription level, into the gene discovery framework for a unique human disease, microcephaly - micromelia syndrome (MMS).

Finally, there are other causes of microcephaly, brain abnormalities, and other birth defects, including genetic and infectious causes, about which the USZPR has limited information.36 - 38

Zika virus infections in pregnant women have been linked to a birth defect called microcephaly, a condition in which the brain and skull are significantly underdeveloped.

Brazil has reported the vast majority of cases of a Zika - linked birth defect called microcephaly, which causes babies to be born with abnormally small heads and malformed brains.