Sentences with word «microcompartment»

«How bacterial organelles assemble: Structure of microcompartment's protein shell could help research in bioenergy, pathogenesis, and biotechnology.»

A different team of scientists presents the first atomic - scale look at a complete bacterial microcompartment in the June 23 Science.

Assembly principles and structure of a 6.5 - MDa bacterial microcompartment shell.

The structure of NpSRII / NpHtrII is related to bacterial chemoreceptors, which were shown to form microcompartments in the cell membranes at the poles of the cell.

Advanced fluorescence microscopy will be complemented by electron microscopy approaches for ultrastructural characterization of cellular microcompartments.

Now, in the Science paper, researchers led by structural biologist Cheryl Kerfeld have used a combination of X-ray crystallography and cryo - electron microscopy to examine microcompartments from the bacterium Haliangium ochraceum and answer those questions.

The results obtained for these subprojects should reveal structural and functional details of the dynamic adhesion / invasion microcompartment formed during Salmonella invasion of host cells.

To address these issues, we work on four aspects: a) Ultrastructural analysis of the interaction microcompartment.

These microorganisms contain microcompartments named carboxysomes that encapsulate Rubisco in a protein shell and contain an enzyme, carbonic anhydrase (CA), which converts bicarbonate ion to CO2.

A conserved machinery is organized in microcompartments for spatiotemporal control of fusion.

Since the 1950s, biologists have known that photosynthetic cyanobacteria make microcompartments, called carboxysomes, which house an important photosynthesis enzyme.

This project aims to elucidate the role of membrane recycling for the lateral segregation of integral membrane proteins into dynamic microcompartments in the budding yeast plasma membrane (PM).

We are using a synthetic biology approach to incorporate microcompartments into chloroplasts that will increase carbon dioxide near Rubisco.

Within this project, we will analyze the activation and turn - over of the endosomal Rab5 (in yeast Vps21) and Rab7 GTPases (in yeast Ypt7), the interplay of these Rabs with the CORVET and HOPS tethering complexes, and the crosstalk with retromer and ESCRT complexes on endosomal microcompartments during their maturation.

Many researchers have worked to engineer microcompartments to make drugs, industrial chemicals or biofuels.

Bacteria use protein shells called microcompartments to concentrate important chemical reactions in one place.

About 20 percent of bacteria — even ones that don't do photosynthesis — have the genes for making similar microcompartments.

Researchers leveraged microfabrication and microfluidic techniques to achieve a system with three vertically stacked fluidic microcompartments separated by nanoporous membranes.

The project focuses on the dynamics of transient microcompartments formed by the V - ATPase holoenzyme, V - ATPase subcomplexes and subunits together with the mentioned proteins, with the aim to understand the mechanisms leading to this unique type of physiologically relevant regulation.

For the current funding period, we aim to explore the mechanistic basis for differential signal activation and its spatiotemporal regulation by localization in different microcompartments.

The key players in this process are the SNAREs (soluble N - ethylmaleimide - sensitive - factor attachment receptors), which drive fusion, and S / M (Sec1 / Munc18) family proteins that act as universal organizers of fusiogenic microcompartments and activators of SNARE - mediated membrane fusion.

Exploring cellular microcompartments fundamentally requires imaging techniques capable to resolve nanoscopic structures.

A typical microcompartment is 100 - 200 nm in size, with a 3 - 4 nm proteinaceous shell.

Within the meshwork of its structural components, the ECM is spatially patterned and thereby provides locally restricted reaction environments and structural microcompartments.

Focus of this project is the CaaX processing microcompartment transiently formed at the ER, which is required for the modification of yeast Chs4, a regulatory subunit of the chitin synthase (CHS) III complex.

We invite original innovative research on the rational engineering of plant systems at all levels, including proteins, protein complexes, sensors, metabolic and signalling pathways, microcompartments such as carboxysomes, subcellular compartments, cell types or tissues, as well as the engineering of novel plant hybrid species and the interactions of plants with viruses, bacteria, and other organisms.

Researchers at Berkeley Lab and MSU have obtained the first atomic - level view of an intact bacterial microcompartment, shown here.

We propose an adhesion / invasion microcompartment at the host - pathogen interface with SiiE - mediated membrane contact sites, functional effector translocation and recruitment of the host cell actin organizing machinery.

RNA granules can be considered as dynamic cellular microcompartments that contain a subset of different mRNA species and various mRNA - binding proteins.

The project will focus on the functional and structural analyses of the interaction microcompartment.

In this project we plan (i) to correlate the redox - states of the pertinent compartments with the subcellu - lar localization of GapC (as a fusion with GFP) and its varying functions, (ii) to characterize the spatio - temporal dynamics of the cytosolic and nuclear GapC - containing microcompartments, and (iii) to finally determine their special functions in redox signaling and gene expression.

Transient expression of cyanobacterial carboxysome proteins in tobacco chloroplasts resulted in assembly of microcompartments.

For instance, some pathogenic bacteria form microcompartments to help them digest mucus from people's intestines, Warren says.

Unlike the lipid - based membranes of eukaryotic cells, bacterial microcompartments (BMCs) have polyhedral shells made of proteins.

The microcompartment shell provides a selectively permeable barrier which separates the reactions in its interior from the rest of the cell.

Understanding how the microcompartment membrane is assembled, as well as how it lets some compounds pass through while impeding others, could contribute to research in enhancing carbon fixation and, more broadly, bioenergy.

These organelles, or bacterial microcompartments (BMCs), are used by some bacteria to fix carbon dioxide, Kerfeld noted.

Scientists are providing the clearest view yet of an intact bacterial microcompartment, revealing at atomic - level resolution the structure and assembly of the organelle's protein shell.

Microcompartments aren't the only mysterious structures inside bacteria.

Now researchers have constructed a complete 3 - D model of a microcompartment from a saltwater bacterium called Haliangium ochraceum.

The cups cover the outsides of the microcompartments, like dimples on a golf ball, says Kerfeld of Michigan State University in East Lansing and the Lawrence Berkeley National Laboratory in California.

But it wasn't clear whether the cup or the bulge went on the inside of the microcompartment.

Microcompartments are protein shells that bacteria use to keep certain chemical reactions separate from the rest of the cell.

Knowing how the microcompartment is assembled could have important applications in biotechnology and medicine, the researchers say.

Kerfield's lab studies bacterial microcompartments, or BMCs.

Advanced imaging techniques for resolving cellular microcompartments.

Yeast cytokinesis occurs at the microcompartment of the bud neck and involves the controlled synthesis of cell wall components.

We also investigate the homeostatic mechanisms of ceramide biogenesis in a microcompartment of the ER and how these mechanisms are integrated in cellular life - death decisions.

We analyze the protein interactions between the constituents of this microcompartment in vitro, and the dynamics of complex assembly and disassembly in vivo.

c) Characterization of bacterial and host cell proteins involved in the formation of the adhesion / invasion microcompartment.