Sentences with word «microelectrode»

Researchers at the University of Southern California Viterbi School of Engineering have developed thin, flexible polymer - based materials for use in microelectrode arrays that record activity more deeply in the brain and with more specific placement than ever before.
For example, in nonhuman primates, stimulation using microelectrodes improved face categorization (Afraz et al., 2006), modulated motion perception with great specificity (Fetsch et al., 2014), and increased the learning rate during a reinforcement learning task (Williams and Eskandar, 2006).
Linsenmeier et al. [1] measured intraretinal PO2 with microelectrodes in cats with long - standing diabetes and concluded that the retina was hypoxic in the early stages of retinopathy.
We recorded neural population activity with arrays of microelectrodes implanted in the PPC of a tetraplegic subject.
By painstakingly recording the activity of individual granule cells with microelectrodes in a living electric fish, neuroscientist Nate Sawtell of Columbia University's Kavli Institute for Brain Science, where I am currently a Ph.D. candidate, has uncovered some of the first direct evidence in support of the 1960s theory that granule cells may enhance the cerebellum's ability to learn skills such as fine movements.
We have described these responses, since they have not been previously reported and since they illustrate an important difference between the information which can be gleaned from experiments of this type and that obtained in the usual «acute» microelectrode experiment.
But the number of neurons at a time with which microelectrode arrays can interface must be increased several-fold while making sure the scale - up does not cause damage to brain tissue.
In one early experiment carried out with fellow neuroscientist John K. Chapin, Ph.D., Nicolelis used brain - implanted microelectrodes to record the brain activity of rats trained to pull a robotic lever to get a sip of water.
Australian neurophysiologist John Eccles and his colleagues in 1951 first managed to insert miniscule - tipped probes called microelectrodes directly into a neuron from the central nervous system to measure its responses to signals from neighboring neurons.
At the same time, the activity of hundreds of nerve cells was measured with so - called microelectrode arrays.
In addition, the polymer - based material, called Parylene C, is less invasive and damaging to surrounding cells and tissue than previous microelectrode arrays comprised of silicon or microwires.
A study published online Oct. 13 in the journal Current Biology describes how researchers used metal microelectrodes in a jumping spider's poppy - seed - sized brain to show that auditory neurons can sense far - field sounds, at distances up to 3 meters, or about 600 spider body lengths.
Thin - film microelectrode arrays produced at Lawrence Livermore National Laboratory (LLNL) have enabled development of an automated system to sort brain activity by individual neurons, a technology that could open the door to recording and analyzing unprecedented amounts of neural signals over time...
Simulated and optimized different 3D microelectrode array designs for micro-biofuel cell and microbatteries using COMSOL multiphysics.
Hubel and Wiesel inserted tiny, pin - shaped microelectrodes directly into a cat's visual cortex to measure the activity there.
In addition to inflammation, previous microelectrode brain implants made of silicon or microwire have caused neuronal death and glial scarring, which is damage to connective tissue in the nervous system.
Also, the team plans to create devices with even higher density, including a double - sided microelectrode array with 64 electrodes per tine instead of eight — making for a total of around 4,000 electrodes placed in the brain at once.
«This is a beautiful example of how if you design a study correctly, it can go quickly,» said Dr. Greg Gerhardt, director of the Parkinson's Disease Translational Research Center of Excellence and of the Center for Microelectrode Technology.
Instead, Menda's method creates a very tiny hole that seals, like a self - sealing tire, around a hair - sized tungsten microelectrode.
To investigate the direct impact of VTA activation on primate behavior, the research team used high - resolution magnetic resonance imaging to guide the placement of microelectrodes within the VTAs of macaque monkeys.
In the experiment, monkeys learned to control a computer cursor — a stand - in for a bionic limb — through microelectrodes wiretapping their motor cortex.
The device, part of the Lab's iCHIP (in - vitro Chip - Based Human Investigational Platform) project, simulates the central nervous system by recording neural activity from multiple brain cell types deposited and grown onto microelectrode arrays.
They used a penetrating microelectrode array of 64 electrodes arranged in a grid on the tissue, to record the activity.
Now insert microelectrodes at strategic points in the tissue.
More than a decade ago microelectrode studies of rats and monkeys revealed place cells that respond when the animals move to a particular spot in a maze.
Protruding from the end of each macroelectrode are as many as 10 flexible microelectrodes that can detect the pulses of individual neurons.
To test whether similar techniques could improve episodic memory in humans, we implemented a microstimulation technique that allowed delivery of low - current electrical stimulation via 100 μm - diameter microelectrodes.
In a recent publication in the Journal of the American Chemical Society, researchers from Dynamic Biosensors and the Kurt - Schwabe - Institut Meinsberg have demonstrated the persistent electrical actuation of a large DNA - origami nanostructure on a gold microelectrode.
Dopamine release was measured from the region of the nucleus accumbens, using carbon fibre microelectrodes and fast cyclic voltammetry to electrically measure the oxidations of dopamine.
Microelectrode measurements and pharmacological inhibitor studies carried out on larval stages demonstrated that maintenance of alkaline gastric pH represents a substantial energy sink under acidified conditions that may contribute up to 30 % to the total energy budget.
◊ general surgery of the laboratory animal with application to neurobiology (neuroanatomy, neuro - histology and neurosurgery): neurology module, April 3 - 7 and June 12 - 13 in Toulouse (ENVT, Anexplo) ◊ neurosurgery on rodent model: dates not defined, Marseille (CE2F - PRIM, NSRepair) ◊ insertion of microelectrodes on primates: April 24 - 26, Marseille (CE2F - PRIM, Blackrock Microsystems)
Designed and fabricated novel carbon based BioMEMS platforms to investigate fundamental processes and demonstrated on - chip enzymatic biofuel cells with 3 - D microelectrodes.
Vahidi, N., Hirabayashi, M., Mehta, B, Khosla, A., and Kassegne, S., «Bionanoelectronics Platform with DNA Molecular Wires Attached to High Aspect - Ratio 3D Metal Microelectrodes», ECS Journal of Solid State Science and Technology 3 (3), Q29 - Q36 2014.
Dec. 12, 2017 - Thin - film microelectrode arrays produced at Lawrence Livermore National Laboratory (LLNL) have enabled development of an automated system to sort brain activity by individual neurons, a technology that could open the door to recording and analyzing unprecedented amounts of neural signals over time...
At the same time, she measured electrical signals in neighboring neurons using microelectrodes that can record small voltage changes across a neuron's membrane.
Microelectrodes in a clear silicon array rest on the brain surface.
The surface of the chip is covered with microelectrodes and the chip is connected to a power source, with the power converted to high - frequency sound waves.
But no one had ever put a large number of microelectrodes into a paralyzed person; indeed, no one knew whether neurons in the motor cortex, the brain region primarily responsible for movement control, would still produce decipherable signals after years of disuse.
Aflalo et al. implanted two microelectrode arrays in the posterior parietal cortex of a tetraplegic patient (see the Perspective by Pruszynski and Diedrichsen).
Julian Dindas, a PhD student at Hedrich's department, used microelectrodes that register the electric voltage of the root hair's cell membrane, the so - called membrane potential, to study the early responses of the cell to a hormone pulse.
What's more is that each microelectrode array is made up of eight «tines,» each with eight microelectrodes which can record from a total 64 subregions of the brain at once.
Meng said that the polymer - based material can conform to a specific location in the hippocampus and «listen in on a conversation» between neurons and because there are many such «eavesdroppers» (the microelectrodes), much more information about neural interconnectivity can be gleaned.
In a new study by Flesher et al., microelectrode arrays were implanted into the primary somatosensory cortex of a person with spinal cord injury and, by delivering current through the electrodes, generated sensations of touch that were perceived as coming from his own paralyzed hand.
Using microelectrodes, the researchers recorded the electrical activity of pheromone - sensitive interneurons in male American cockroaches that relay signals of female - producing sex pheromones in the antennal lobe (functional homolog to the mammalian olfactory bulb) to higher - order centers.
Researchers are probing the brain with increasingly powerful tools, including superfast magnetic resonance imagers and microelectrodes that can detect the murmurs of individual brain cells.
To do so, he uses a microelectrode array that reads his brain's signals and sends them through wires to a gel sleeve that electronically stimulates his muscles.
Lawrence Livermore National Laboratory researchers Heather Enright (left) and Anna Belle hold the brain - on - a-chip device and a microelectrode array.
Once I have the microelectrode array in your motor cortex, the brain's command center for movement, you watch a cursor on a video moving left and right.
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