Sentences with phrase «microenvironment plays»

Furthermore, the role the host microenvironment plays in tumor biology provides an exceptional opportunity for novel therapeutic strategies.

Nervous gut - the enteric nervous system, a so far unnoticed component of the tumor microenvironment, orchestrated by NDRG4 It is well - known that components of the tumor - microenvironment play an important role in the development of colorectal cancer.

The Herlyn lab is differentiating multi-potent stem cells from the human dermis and reprogrammed stem cells into melanocytes to test the hypothesis that melanocyte stem cells are more prone to transformation than fully differentiated cells, and that neighboring cells and matrix in the microenvironment play critical roles in differentiation and transformation.

Not exact matches

«It shows that the egg is playing an active role in creating the microenvironment that it needs to continue its development,» says Dr. Clarke, lead study author, who is also a senior scientist from the Child Health and Human Development Program at the RI - MUHC and a professor and research director of the Department of Obstetrics and Gynecology at McGill University.

«Our research has identified the right soil for seeds to flourish by looking at the microenvironment in the breast and examining the mechanisms at play.

«Our research shows that the protein GSK3 plays a crucial role in helping B cells meet the energy needs of their distinct states,» says Robert Rickert, Ph.D., director of the Tumor Microenvironment and Cancer Immunology Program at Sanford Burnham Prebys Medical Discovery Institute (SBP).

Entinostat Therapy Plays Favorable Role in Targeting the Tumor Microenvironment to Enhance Immune Checkpoint Therapy

Ongoing projects are directed toward understanding the role that the alpha2 beta1 integrin plays in immune modulation in the tumor microenvironment.

I will investigate whether the enteric nervous system, an neglected member of the tumor - microenvironment, plays a role in the development of colorectal cancer and can be used as a potential therapeutic target.

To directly examine whether ABL kinases play a role in regulating the colonization and survival of breast cancer cells in the bone microenvironment, we injected control or ABL1 / ABL2 knockdown breast cancer cells directly into the tibia of immunodeficient mice.

These findings suggest mechanical forces in the early embryo's microenvironment may play a bigger role in its development than scientists had realized.

Carcinoma - associated fibroblasts (CAFs) are a highly enriched cell population in the tumor microenvironment that plays an important role in cancer invasion.